Lupus Erythematosus, Discoid clinical trials
The registry lists 42 studies for Lupus Erythematosus, Discoid across more than 10 countries. 7 are recruiting or about to start. 29 of them are mainly about Lupus Erythematosus, Discoid (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
Get an email when these change. Save the Lupus Erythematosus, Discoid studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
EMD Serono Research & Development Institute, Inc. (4) · Amgen (3) · Biogen (3) · Astion Pharma A/S (2) · Bristol-Myers Squibb (2) · Janssen Research & Development, LLC (2) · Tufts Medical Center (1) · Kunming Pharmaceuticals, Inc. (1)
What is being tested here
Drugs under test in Lupus Erythematosus, Discoid studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Enpatoran | 3 | 3 | 5 |
| Litifilimab | 1 | 2 | 2 |
| Artenimol | 1 | 0 | 1 |
| Afimetoran | 1 | 1 | 1 |
| Etanercept | 0 | 0 | 2 |
| Levalbuterol | 0 | 0 | 2 |
| Pimecrolimus | 0 | 0 | 2 |
| Anifrolumab | 0 | 1 | 1 |
| Imeroprubart | 0 | 0 | 1 |
| Deucravacitinib | 0 | 0 | 1 |
Drug classes tested here JAK inhibitors 4 · Tyrosine kinase inhibitors (TKIs) 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
Who these studies take
Of the 5 Lupus Erythematosus, Discoid studies recruiting now, 2 (40%) set no upper age limit and 2 (40%) stop at 75 or younger. 1 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 2 (40%) | 2 (40%) |
Across all 42 studies, recruiting or not: 57% stop at 75 or younger and 19% at 65; 7% take children; 2% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting2
Newly registered1
- Study of Afimetoran in Adults With Cutaneous Lupus ErythematosusOct 19, 2026NCT07881120
Studies
Recruiting first, then most recently updated. Showing 42 of 42. search them.
- A Long-Term Extension (LTE) Study Of Enpatoran In Cutaneous Manifestations Of Lupus With Or Without Systemic Disease [Elowen-LTE]RecruitingNCT07840287Phase 31 country
- Study of Afimetoran in Adults With Cutaneous Lupus ErythematosusRecruitingNCT07881120Phase 2/31 country
- A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic DiseaseRecruitingNCT07332481Phase 320 countries
- A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)RecruitingNCT07355218Phase 320 countries
- A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus ErythematosusEnrolling by invitationNCT06044337Phase 325 countries
- A Multicentre, Randomised, Double-blind, Positive-control Clinical Trial Evaluating Dihydroartemisinin Tablets for the Treatment of Discoid Lupus ErythematosusNot yet recruitingNCT07557927Phase 21 country
- Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects with Discoid Lupus ErythematosusRecruitingNCT06261021Phase 21 country
- A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus ErythematosusActive, not recruitingNCT06015737Phase 332 countries
- A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus ErythematosusActive, not recruitingNCT05531565Phase 2/330 countries
- The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)Active, not recruitingNCT05540327Phase 222 countries
- A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)Active, not recruitingNCT06980805Phase 213 countries
- A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of LupusCompletedNCT06013995Phase 18 countries
- Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus ErythematosusTerminatedNCT05591222Phase 211 countries
- The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW)CompletedNCT05162586Phase 222 countries
- A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)Active, not recruitingNCT04857034Phase 28 countries
- Study of Ruxolitinib Cream for the Treatment of Discoid Lupus ErythematosusCompletedNCT04908280Phase 21 country
- Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.TerminatedNCT03958955Phase 24 countries
- Topical Nicotinamide in Treatment of DLECompletedNCT05362188Early Phase 11 country
- Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE)TerminatedNCT03159936Early Phase 11 country
- A Study to Assess the Safety and Efficacy of Secukinumab in Alleviating Symptoms of Discoid Lupus ErythematosusWithdrawnNCT03866317Phase 21 country
- Phase Ib Study of SC Milatuzumab in SLECompletedNCT01845740Phase 11 country
- Safety Study of Clinical and Immune Effects of Phosphodiesterase 4 (PDE-4) Inhibitor in Cutaneous Lupus PatientsCompletedNCT00708916Phase 1/21 country
- To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus ErythematosusCompletedNCT01300208Phase 21 country
- Discoid Lupus Erythematosus of the Scalp and a Trial of Biologic Therapy With RaptivaWithdrawnNCT00308204Phase 21 country
- A Research Study to Assess if CC-930 is Safe in Treating Subjects With Discoid Lupus ErythematosusTerminatedNCT01466725Phase 21 country
- Autologous Polyclonal Tregs for LupusTerminatedNCT02428309Phase 11 country
- Targeted Therapy Using Intradermal Injection of Etanercept for Remission Induction in Discoid Lupus ErythematosusCompletedNCT02656082Phase 21 country
- Expression of Fas Protein in Skin Biopsies of Participants With Scarring AlopeciaCompletedNCT006917691 country
- Cutaneous Lupus Erythematosus and ElidelWithdrawnNCT00222183Not applicable1 country
- Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus ErythematosusStatus unknownNCT03178188Phase 2/31 country
- A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy VolunteersCompletedNCT020343446 countries
- Pilot Tape Harvesting StudyCompletedNCT021256951 country
- Safety and Efficacy of Topical R333 in Patients With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) LesionsCompletedNCT01597050Phase 22 countries
- Efficacy and Safety of Oral Alitretinoin (Toctino®) in the Treatment of Patients With Cutaneous Lupus ErythematosusTerminatedNCT01407679Phase 21 country
- Safety Study of AMG 811 in Subjects With Discoid Lupus ErythematosusTerminatedNCT01164917Phase 11 country
- A Non-drug Study Profiling Cutaneous LupusCompletedNCT019234152 countries
- A Pooled Analysis of the HGS1006-C1056 (BLISS-52) and HGS1006-C1057 (BLISS-76) StudiesCompletedNCT01858792
- The Safety and Efficacy of Etanercept (Enbrel®) for the Treatment of Discoid Lupus ErythematosusStatus unknownNCT00797784Phase 21 country
- A Pilot Trial of Topical Thalidomide for the Management of Chronic Discoid Lupus ErythematosusCompletedNCT00001680Phase 21 country
- Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) LesionsCompletedNCT00625521Phase 21 country
- Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions (2)CompletedNCT00625157Phase 21 country
- Comparing the Therapeutic Efficacy of Pimecrolimus Cream With Betamethasone Cream for Discoid Lupus ErythematosusCompletedNCT00608673Not applicable1 country