Leiomyosarcoma: all 149 studies
Page 1 of 2. Open to participants first (33), then studies with results posted, then the rest; newest registration first within each.
- A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic TherapyRecruitingNCT07633756Phase 1
- Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid TumorsRecruitingNCT07628634Early Phase 1
- A Study of Ivonescimab in People With LeiomyosarcomaRecruitingNCT07516925Phase 2
- Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma PatientsRecruitingNCT07432932
- Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma.RecruitingNCT07173972Phase 2
- Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue SarcomaRecruitingNCT07169344Phase 2
- Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic LeiomyosarcomaRecruitingNCT07125183Phase 2
- STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected SarcomasRecruitingNCT06975293Phase 1/2
- Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatientsRecruitingNCT06875700
- IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)RecruitingNCT06849986Phase 2
- A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid TumorsRecruitingNCT06789172Phase 1
- XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue SarcomaRecruitingNCT06571734Phase 2
- Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced LeiomyosarcomaRecruitingNCT06528769Phase 2
- Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue SarcomaNot yet recruitingNCT06526897Not applicable
- The Role of Pre-Surgical Tru - Cut Biopsy in the Management of Atypical Myometrial LesionsNot yet recruitingNCT06521060
- Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue SarcomaRecruitingNCT06498648Phase 1/2
- MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue SarcomaRecruitingNCT06277154Phase 2
- NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)RecruitingNCT06239272Phase 1/2
- Study on the Quality of Life and Pathological State in Patients Who Underwent Radical CystectomyRecruitingNCT06170177
- Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced SarcomaRecruitingNCT05711615Phase 1
- Metastatic Leiomyosarcoma Biomarker ProtocolRecruitingNCT05653388
- Exploring Clinical Trial Experiences of People With LeiomyosarcomaNot yet recruitingNCT05548179
- Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone SarcomasNot yet recruitingNCT05515068
- AOH1996 for the Treatment of Refractory Solid TumorsRecruitingNCT05227326Phase 1
- A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer AgentsRecruitingNCT05094804Phase 1/2
- Localized Leiomyosarcoma Biomarker ProtocolRecruitingNCT04925089
- Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue SarcomaRecruitingNCT04535271Phase 2
- Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone SarcomasRecruitingNCT04055220Not applicable
- Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal SarcomaRecruitingNCT04031677Phase 3
- Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA)RecruitingNCT03420014Phase 2
- Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)RecruitingNCT03016819Phase 3
- Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma PatientsRecruitingNCT02275286Phase 1/2
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168
- A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)TerminatedNCT05269355Phase 2/3Results posted
- Nanatinostat Plus Valganciclovir in Advanced EBV+ Solid Tumors and in Combination With Pembrolizumab in EBV+ RM-NPCTerminatedNCT05166577Phase 1Results posted
- ATX-101 in Advanced Dedifferentiated Liposarcoma and LeiomyosarcomaTerminatedNCT05116683Phase 2Results posted
- A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With LeiomyosarcomaTerminatedNCT04996004Phase 2Results posted
- A Study of Rucaparib and Nivolumab in People With LeiomyosarcomaActive, not recruitingNCT04624178Phase 2Results posted
- Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue SarcomaActive, not recruitingNCT04200443Phase 2Results posted
- A Study of LY3435151 in Participants With Solid TumorsTerminatedNCT04099277Phase 1Results posted
- A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue SarcomasCompletedNCT03899805Phase 2Results posted
- M6620 (VX-970) in Selected Solid TumorsCompletedNCT03718091Phase 2Results posted
- Lenvatinib and Eribulin in Advanced Soft Tissue SarcomaCompletedNCT03526679Phase 1/2Results posted
- Vorinostat (SAHA) in Uterine SarcomaTerminatedNCT03509207Phase 2Results posted
- A Study of Nivolumab in Selected Uterine Cancer PatientsCompletedNCT03241745Phase 2Results posted
- Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by SurgeryTerminatedNCT03074318Phase 1/2Results posted
- Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic SarcomaTerminatedNCT02601209Phase 1/2Results posted
- Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue SarcomaCompletedNCT02584309Phase 2Results posted
- A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue SarcomaCompletedNCT02451943Phase 3Results posted
- Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine LeiomyosarcomaCompletedNCT02428192Phase 2Results posted
- Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II TrialCompletedNCT02406781Phase 2Results posted
- SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic LeiomyosarcomaCompletedNCT02303262Phase 2Results posted
- Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by SurgeryCompletedNCT02180867Phase 2/3Results posted
- Gemcitabine Hydrochloride, Docetaxel, and Radiation Therapy in Treating Patients With Uterine Sarcoma That Has Been Removed By SurgeryTerminatedNCT01958580Not applicableResults posted
- Alisertib in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01653028Phase 2Results posted
- Alisertib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the UterusCompletedNCT01637961Phase 2Results posted
- Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory SarcomaCompletedNCT01614795Phase 2Results posted
- Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by SurgeryTerminatedNCT01533207Phase 3Results posted
- Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue SarcomaCompletedNCT01532687Phase 2Results posted
- Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)TerminatedNCT01418001Phase 1/2Results posted
- A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or LeiomyosarcomaCompletedNCT01343277Phase 3Results posted
- Ixabepilone in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus Previously Treated With ChemotherapyCompletedNCT01220609Phase 2Results posted
- Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01154452Phase 1/2Results posted
- Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma SubtypesCompletedNCT00887809Phase 2Results posted
- Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine LeiomyosarcomaCompletedNCT00856050Phase 2Results posted
- Sorafenib and Dacarbazine in Soft Tissue SarcomaCompletedNCT00837148Phase 2Results posted
- A Five-Tier, Open-Label Study of IMC-A12 in Advanced SarcomaCompletedNCT00668148Phase 2Results posted
- AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue SarcomaCompletedNCT00659360Phase 2Results posted
- Letrozole Versus Observation in Patients With Newly Diagnosed Uterine LeiomyosarcomaTerminatedNCT00414076Phase 2Results posted
- Phase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue SarcomaCompletedNCT00400569Phase 2Results posted
- Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue SarcomaCompletedNCT00390234Phase 2Results posted
- Trabectedin in Treating Patients With Advanced, Persistent, or Recurrent Leiomyosarcoma of the UterusCompletedNCT00379145Phase 2Results posted
- Bevacizumab and Radiation Therapy for SarcomasCompletedNCT00356031Phase 2Results posted
- Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue SarcomaCompletedNCT00346164Phase 3Results posted
- Adjuvant Chemotherapy for High Risk Uterine LeiomyosarcomaCompletedNCT00282087Phase 2Results posted
- Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent SarcomaCompletedNCT00245102Phase 2Results posted
- Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue SarcomaCompletedNCT00112463Phase 2Results posted
- LMP-specific T-cells for Patients With Relapsed EBV-positive LymphomaCompletedNCT00062868Phase 1Results posted
- A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced CancerCompletedNCT00060944Phase 2Results posted
- Combined CRS With HIPEC in Women With Inadvertently Morcellated uLMSCompletedNCT06678763
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 2
- A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or DeletionsActive, not recruitingNCT06308419Phase 1
- NM32-2668 in Adult Patients With Selected Advanced Solid TumorsTerminatedNCT06299163Phase 1
- Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine FibroidsActive, not recruitingNCT06244251Not applicable
- Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)Active, not recruitingNCT06088290Phase 3
- Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene AmplificationsTerminatedNCT05827614Phase 1
- Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)TerminatedNCT05712694Phase 3
- Circulating " Cancer Cells / Macrophage " HYbrid Cells in Patients With Sarcoma, Part 2Active, not recruitingNCT05427461Not applicable
- Temozolomide for Injection Combined With Epirubicin in First-line Treatment of LeiomyosarcomaStatus unknownNCT05204524Not applicable
- Niraparib for the Treatment of LeiomyosarcomaWithdrawnNCT05174455Phase 2
- Phase 2 Study of 9-ING-41 With Chemotherapy in SarcomaWithdrawnNCT05116800Phase 2
- Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With LeiomyosarcomaCompletedNCT05080790Phase 2
- Accuracy of the Preoperative Molecular Diagnosis of Uterine Tumors by Liquid BiopsyStatus unknownNCT04935333
- A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced SarcomasWithdrawnNCT04906876Phase 2
- A Study of Different Dosing Schedules of Selinexor in Sarcoma PatientsCompletedNCT04811196Phase 1
- Targeting ATR in Soft-tissue SarcomasCompletedNCT04807816Phase 2
- A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated DiseasesActive, not recruitingNCT04554914Phase 2
- Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue SarcomaActive, not recruitingNCT04420975Phase 1
- Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic SarcomasCompletedNCT04242238Phase 1
- Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and LeiomyosarcomasStatus unknownNCT04214457