Lacrimal Apparatus Diseases clinical trials
The registry lists 36 studies for Lacrimal Apparatus Diseases across more than 10 countries. 2 are recruiting or about to start. 22 of them are mainly about Lacrimal Apparatus Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-14. Counting its 5 narrower conditions too, such as Dry Eye Syndromes: 1,731 studies, 304 open.
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Who runs them
Menoufia University (3) · Instituto de Oftalmología Fundación Conde de Valenciana (2) · Rehan Ahmed (2) · Minia University (2) · Novartis Pharmaceuticals (1) · Benha University (1) · Louisiana State University Health Sciences Center in New Orleans (1) · Uludag University (1)
What is being tested here
Drugs under test in Lacrimal Apparatus Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Atropine | 1 | 0 | 2 |
| Proxymetacaine | 0 | 0 | 2 |
| Sodium Chloride | 0 | 0 | 2 |
| Potassium Chloride | 0 | 0 | 2 |
| Calcium Chloride | 0 | 0 | 2 |
| Magnesium Chloride | 0 | 0 | 2 |
| Sodium Acetate | 0 | 0 | 2 |
| Sodium Citrate | 0 | 0 | 2 |
| Citric Acid | 0 | 0 | 2 |
| Lubricant Eye Drops | 0 | 0 | 2 |
Drug classes tested here Local anesthetics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Nov 2026Low-Dose Atropine Eye Drops for Excessive Tearing (Epiphora) · Rehan Ahmed
Who these studies take
Of the 1 Lacrimal Apparatus Diseases studies recruiting now, 1 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (100%) | 1 (100%) |
| 30 | 1 (100%) | 1 (100%) |
| 40 | 1 (100%) | 1 (100%) |
| 50 | 1 (100%) | 1 (100%) |
| 65 | 1 (100%) | 1 (100%) |
| 75 | 1 (100%) | 1 (100%) |
| 85 | 1 (100%) | 1 (100%) |
Across all 36 studies, recruiting or not: 19% stop at 75 or younger and 8% at 65; 14% take children; 3% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 36 of 36. search them.
- Low-Dose Atropine Eye Drops for Excessive Tearing (Epiphora)RecruitingNCT07816224Phase 21 country
- Outcomes of Stentless Dacryocystorhinostomy in Primary Acquired Nasolacrimal Duct Obstruction.Not yet recruitingNCT07848932Not applicable
- Atropine Eye Drops for Watery Eyes (Excessive Tearing)CompletedNCT07676981Phase 21 country
- External Versus Powered Endoscopic Dacryocystorhinostomy With Mitomycin C for Primary Acquired Nasolacrimal Duct ObstructionCompletedNCT07754058Not applicable1 country
- SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct ObstructionTerminatedNCT03705000Not applicable1 country
- A Comparative Analysis of the Effectiveness of Nepafenac Combined With a Lubricant Versus a Lubricant Alone in the Treatment of Epiphora Associated With Lacrimal Punctum StenosisActive, not recruitingNCT07372014Phase 41 country
- Lacrimal Deroofing for Epiphora From Punctal AbnormalitiesCompletedNCT048989331 country
- Examination of Lacrimal Sac and Nasal Mucosa Preparations Taken in Dacryocystorhinostomy Surgery of Patients With Nasolacrimal Duct Obstruction and Comparison of Clinical Groups With Each OtherCompletedNCT068100891 country
- Closed Dacryointubation vs Bicanalicular Intubation for Proximal Tear Duct ObstructionCompletedNCT06428266Not applicable1 country
- Innovative Imaging of the Conjunctiva, Cornea, and Ocular AdnexaCompletedNCT02386774Not applicable1 country
- A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's SyndromeTerminatedNCT04035668Phase 212 countries
- Does Topical Ophthalmic Anesthetic Prior to Probing and Irrigation Decrease Pain?TerminatedNCT04229771Phase 41 country
- Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?Status unknownNCT05663684Phase 41 country
- Bupivacaine Epiphora TrialWithdrawnNCT03266081Phase 21 country
- Design of an Augmented Reality System by Integration of CT Scan or MRI Data With Endoscopic Images for Video-assisted Endonasal Endoscopic SurgeryStatus unknownNCT049685611 country
- Comparative Study Between Wide and Narrow Fenstrum Endoscopic DCRStatus unknownNCT04833452Not applicable1 country
- Placement of Three Interrupted Sutures After Triangular Three-snip PunctoplastyStatus unknownNCT04680078Not applicable1 country
- Topical Cyclosporine-A for Management of EpiphoraCompletedNCT04637633Phase 2/31 country
- Level of Lacrimal Passage ObstructionCompletedNCT042404311 country
- Tear Lipid Layer Thickness Changes With Use of Emollient and Non-Emollient Eye DropsCompletedNCT03706443Not applicable1 country
- Management of Lower Punctal Stenosis.CompletedNCT03731143Not applicable
- Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry EyeStatus unknownNCT03436576Phase 31 country
- Diagnosis of Acquired Punctal Stenosis Using Anterior Segment Optical Coherence TomographyStatus unknownNCT03498144
- Perforated Punctal Plugs for Treatment of Papillary Conjunctivitis in Otherwise Healthy PatientsCompletedNCT02503956Not applicable1 country
- Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye DiseaseTerminatedNCT01072526Phase 21 country
- Analysis of 86 Dacryoliths at the University Hospital OstravaCompletedNCT018267341 country
- Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome.Status unknownNCT02849093
- The Sinopsys Lacrimal Stent for Lacrimal System Repair in EpiphoraCompletedNCT02240615Early Phase 11 country
- Lacrimal Drainage Resistance StudyCompletedNCT017662321 country
- Determination of the Optimum Delivery Route for Botulinum Toxin A in Patients With EpiphoraCompletedNCT01282541Phase 21 country
- Topical Cyclosporine vs. Placebo for Epiphora Associated With DocetaxelWithdrawnNCT00824811Phase 2
- Lacrimal Drainage System Obstruction Associated to Radioactive Iodine Therapy for Thyroid CarcinomaStatus unknownNCT01579344Not applicable1 country
- The Safety and Efficacy of Lacrimal Silicone Intubation for the Management of EpiphoraCompletedNCT01010659Phase 41 country
- Prevention of Docetaxel Induced DacryostenosisCompletedNCT00266838Phase 11 country
- Follow up of Nasolacrimal Intubation in AdultsCompletedNCT007062511 country
- DHEA Treatment for Sjogren's SyndromeCompletedNCT00001598Phase 21 country