Lacrimal Duct Obstruction clinical trials
The registry lists 41 studies for Lacrimal Duct Obstruction across more than 10 countries. 8 are recruiting or about to start. 36 of them are mainly about Lacrimal Duct Obstruction (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
Get an email when these change. Save the Lacrimal Duct Obstruction studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
University Hospital Ostrava (3) · Jaeb Center for Health Research (3) · Zhongshan Ophthalmic Center, Sun Yat-sen University (2) · Instituto de Oftalmología Fundación Conde de Valenciana (2) · Minia University (2) · Shaare Zedek Medical Center (1) · Menoufia University (1) · Kuopio University Hospital (1)
What is being tested here
Drugs under test in Lacrimal Duct Obstruction studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Nov 2026Efficacy and Safety of Piclosept in the Complex Treatment of Neonatal Dacryocystitis · Kazakh Eye Research Institute
Who these studies take
Of the 5 Lacrimal Duct Obstruction studies recruiting now, 3 (60%) set no upper age limit and 2 (40%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (40%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (80%) | 4 (80%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 4 (80%) | 4 (80%) |
| 75 | 4 (80%) | 4 (80%) |
| 85 | 3 (60%) | 3 (60%) |
Across all 41 studies, recruiting or not: 44% stop at 75 or younger and 39% at 65; 44% take children; 0% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 41 of 41. search them.
- Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid CancerRecruitingNCT05999630Phase 31 country
- Outcomes of Stentless Dacryocystorhinostomy in Primary Acquired Nasolacrimal Duct Obstruction.Not yet recruitingNCT07848932Not applicable
- Outcomes of Early Lacrimal Probing Versus Lacrimal Sac Massage in Infants With Congenital Nasolacrimal Duct ObstructionNot yet recruitingNCT07593469Not applicable
- Comparative Outcomes of Four Versus Two Balloon Inflation Points in Dacryoplasty for Primary Acquired Nasolacrimal Duct ObstructionRecruitingNCT07225244Not applicable1 country
- Efficacy Evaluation of 5-Fluorouracil as an Adjuvant to Endoscopic Dacryocystorhinostomy in Managing Primary Acquired Nasolacrimal Duct Obstruction With Small Lacrimal Sac: A Randomized Controlled StudyRecruitingNCT07154121Not applicable1 country
- Effect of Standardized Lacrimal Sac Massage Compared With Probing for Congenital Lacrimal Duct ObstructionNot yet recruitingNCT06924723Not applicable
- Evaluation of Different Methods of Posterior Flap Management in External DacryocystorhinostomyRecruitingNCT06530264Not applicable1 country
- The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective StudyRecruitingNCT06346561Not applicable1 country
- Efficacy and Safety of Piclosept in the Complex Treatment of Neonatal DacryocystitisActive, not recruitingNCT07875517Phase 41 country
- Amniotic Membrane for DacryocystorhinostomyCompletedNCT06226181Not applicable1 country
- Portable Endoscopic Camera System Using Modified Action Camera for Endoscopic Sinunasal ExaminationCompletedNCT072898541 country
- Examination of Lacrimal Sac and Nasal Mucosa Preparations Taken in Dacryocystorhinostomy Surgery of Patients With Nasolacrimal Duct Obstruction and Comparison of Clinical Groups With Each OtherCompletedNCT068100891 country
- Closed Dacryointubation vs Bicanalicular Intubation for Proximal Tear Duct ObstructionCompletedNCT06428266Not applicable1 country
- Clinical Study of Lacrimal Drainage Obstruction Diseases Using DacryoendoscopyCompletedNCT05999058Not applicable1 country
- Does Topical Ophthalmic Anesthetic Prior to Probing and Irrigation Decrease Pain?TerminatedNCT04229771Phase 41 country
- Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?Status unknownNCT05663684Phase 41 country
- Long Term Effectiveness of Dacryocystorinostomy With and Without Bicanalicular IntubationCompletedNCT03960996Not applicable1 country
- Color Doppler Ultrasound in Lacrimal Sac Space-occupying LesionsCompletedNCT055009501 country
- A Feasibility Study to Develop a Protocol for Functional Lacrimal Magnetic Resonance ImagingCompletedNCT03411889Not applicable1 country
- Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy OperationStatus unknownNCT05241054Not applicable1 country
- Low Temperature Plasma Ablation Combined Lacrimal Duct Catheterization in the Treatment of Lacrimal Duct ObstructiveStatus unknownNCT04943055Not applicable1 country
- Nasolacrimal Duct ObstructionCompletedNCT049311861 country
- Self-retaining Bicanalicular Intubation Stent Versus Bicanalicular Silicone Tube for Management of Canalicular ObstructionStatus unknownNCT04706117Not applicable
- Endoscopic Dacryocystorhinostomy Prospective ResearchStatus unknownNCT00571129Not applicable1 country
- Risk and Importance of Peroperative Nasal Hemorrhage in the Treatment of Lacrimal Duct Obstruction in Young ChildrenCompletedNCT028516411 country
- Recanalization of Congenital Nasolacrimal Duct Obstruction by Endodiathermy Probe and Intubation Versus Intubation OnlyStatus unknownNCT04148170Phase 2/31 country
- Endoscopy Assisted Probing Versus Simple Probing in Primary Congenital Nasolacrimal Duct ObstructionStatus unknownNCT03242681Not applicable1 country
- Euphrasia Eye Drops in Preterm Infants With First Signs of Congestion of Nasolacrimal DuctCompletedNCT04122300Phase 31 country
- External DCR Versus Canalicular SI With MMC in NLDOCompletedNCT03780868Not applicable
- Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LPStatus unknownNCT03318146Not applicable1 country
- A Comparative Study of Two Endoscopic Operations for Lacrimal Duct ObstructionCompletedNCT02636257Phase 1/21 country
- A Comparison of Endonasal Dacryocystorhinostomy With and Without Silicone TubesCompletedNCT00784992Phase 41 country
- Analysis of 86 Dacryoliths at the University Hospital OstravaCompletedNCT018267341 country
- Safety and Efficacy Study of Besivance™ for Treatment of Congenital Nasolacrimal Duct Obstruction in ChildrenCompletedNCT01431170Phase 11 country
- Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months OldCompletedNCT00780741Phase 31 country
- Monocanalicular Versus Bicanalicular Intubation in the Treatment of Congenital Nasolacrimal Duct ObstructionCompletedNCT01233596Phase 31 country
- Lacrimal Drainage Resistance StudyCompletedNCT017662321 country
- Are Corneal Epithelial Defects Related to Changes in Ocular Bacterial Flora in Patients With ANLDOStatus unknownNCT022347001 country
- The Factors That Affected the Outcome of Treatment of Congenital Nasolacrimal Duct ObstructionCompletedNCT020817811 country
- Study of Surgical Procedures for Treatment of Persistent Nasolacrimal Duct Obstruction in Children < 4 Years OldCompletedNCT003153151 country
- Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years OldCompletedNCT003152891 country