Klatskin Tumor clinical trials
The registry lists 82 studies for Klatskin Tumor across more than 10 countries. 27 are recruiting or about to start. 64 of them are mainly about Klatskin Tumor (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (4) · Erasmus Medical Center (4) · National Cancer Institute (NCI) (3) · Azienda Ospedaliera di Padova (2) · Khon Kaen University (2) · RedHill Biopharma Limited (2) · Hepatopancreatobiliary Surgery Institute of Gansu Province (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2)
What is being tested here
Drugs under test in Klatskin Tumor studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Gemcitabine | 2 | 1 | 2 |
| Tislelizumab | 1 | 0 | 1 |
| Pembrolizumab | 1 | 1 | 1 |
| Cisplatin | 1 | 1 | 1 |
| Capecitabine | 0 | 0 | 4 |
| Fluorouracil | 0 | 0 | 3 |
| Binimetinib | 0 | 0 | 1 |
| Rilvegostomig | 0 | 1 | 1 |
| Sacituzumab govitecan | 0 | 0 | 1 |
| Oxaliplatin | 0 | 0 | 1 |
Drug classes tested here Antimetabolites 2 open · Immune checkpoint inhibitors 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Dec 2026Toripalimab Combined With Capecitabine as Postoperative Adjuvant Therapy for Patients With Resectable Advanced Extrahepatic Biliary Tract Cancer · Tianjin Medical University Cancer Institute and Hospital
- Jan 2027PD-1 Antibody Plus GEMOX as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Jun 2027Endobiliary Radiofrequency Ablation for Malignant Biliary Obstruction Due to Perihilar Cholangiocarcinoma · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- Jul 2027Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma · Universitätsklinikum Hamburg-Eppendorf
- Jul 2027Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar Cholangiocarcinoma · Jinbo Yue
- Jul 2027Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective Study · Azienda Ospedaliera di Padova
- Nov 2027DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection. · Maastricht University Medical Center
Who these studies take
Of the 19 Klatskin Tumor studies recruiting now, 11 (58%) set no upper age limit and 5 (26%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 19 (100%) | 19 (100%) |
| 30 | 19 (100%) | 19 (100%) |
| 40 | 19 (100%) | 19 (100%) |
| 50 | 19 (100%) | 19 (100%) |
| 65 | 19 (100%) | 19 (100%) |
| 75 | 16 (84%) | 16 (84%) |
| 85 | 11 (58%) | 11 (58%) |
Across all 82 studies, recruiting or not: 18% stop at 75 or younger and 2% at 65; 7% take children; 0% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 50 of 82. Browse all 82 → or search them.
- Preoperative Right Hepatic Artery Embolization for Locally Advanced Bismuth IIIb and IV Perihilar CholangiocarcinomaRecruitingNCT07326189Not applicable1 country
- Liver Transplantation for Non-resectable Perihilar CholangiocarcinomaRecruitingNCT04993131Not applicable1 country
- Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar CholangiocarcinomaRecruitingNCT07030140Phase 21 country
- Prognostic Evaluation and Systematic Re-Assessment of Cholangiocarcinoma TherapyNot yet recruitingNCT07814586
- Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)RecruitingNCT071618691 country
- Endoscopic Radiofrequency Ablation for Unresectable CholangiocarcinomaRecruitingNCT06175845Not applicable1 country
- Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal CholangiocarcinomaRecruitingNCT06923475Phase 2/31 country
- DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.RecruitingNCT0771743713 countries
- Safety and Efficacy of CD160-Enhanced Autologous Antigen-Specific T-Cells (BTC-Ag-T) in Advanced Biliary Tract CancerRecruitingNCT07614061Phase 11 country
- Endobiliary Radiofrequency Ablation for Malignant Biliary Obstruction Due to Perihilar CholangiocarcinomaRecruitingNCT05546372Not applicable1 country
- LIver TrAnspLantation for Non-resectable Peri-HIlar cholangioCArcinoma (LITALHICA)RecruitingNCT06125769Not applicable1 country
- A Prospective, Single-Arm, Phase II Study: PD-L1 Monoclonal Antibody + Chemoradiotherapy as Bridge Therapy to Liver Transplantation for Locally Advanced Perihilar Cholangiocarcinoma (ACHIEVE-LT)Not yet recruitingNCT07471165Phase 21 country
- TRACE-BTC. Relation of Biomarkers and Patients Reported Quality of Life to Outcomes in Patients With Biliary Tract Cancer: a Real- World CohortNot yet recruitingNCT074544861 country
- PD-1 Antibody Plus GEMOX as Postoperative Adjuvant Therapy in Perihilar CholangiocarcinomaRecruitingNCT05430698Phase 21 country
- Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective StudyNot yet recruitingNCT07311798
- Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar CholangiocarcinomaNot yet recruitingNCT03104569Not applicable1 country
- A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers ScreeningRecruitingNCT071769621 country
- Volume-Restricted Resection for Perihilar CholangiocarcinomaNot yet recruitingNCT07149558
- En Bloc Resection of the Liver and Pancreas With a "Non-touch" Technique Followed by Liver Transplantation to Improve the Overall Survival in Patients With Non-resectable Hilar Cholangiocarcinoma Beyond the Mayo Clinic Transplant CriteriaRecruitingNCT06850753Not applicable1 country
- Stereotactic Body Radiation Therapy After Chemotherapy for Unresectable Perihilar CholangiocarcinomaRecruitingNCT06493734Not applicable2 countries
- Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot StudyRecruitingNCT06964425Not applicable1 country
- Liver Transplantation for Unresectable Perihilar CholangiocarcinomaRecruitingNCT069864861 country
- Treatment of Non-resectable Bile Duct Cancer with Radiofrequency Ablation or Photodynamic TherapyRecruitingNCT05551299Phase 41 country
- Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective StudyRecruitingNCT067208831 country
- A Novel Serological Risk Model for Early Non-invasive Diagnosis of CholangiocarcinomaNot yet recruitingNCT066585871 country
- Endoscopic Scissors Cutting Nasobiliary Duct VS Bilateral Plastic StentRecruitingNCT06106750Not applicable1 country
- Therapeutic Assistance and Decision-making Algorithms in Hepatobiliary Tumor BoardsNot yet recruitingNCT05681949Not applicable1 country
- Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)Active, not recruitingNCT05564403Phase 21 country
- Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)Active, not recruitingNCT06109779Phase 321 countries
- Endoscopy and Radiology-guided Ablation for Inoperable CholangiocarcinomaCompletedNCT05563870Not applicable1 country
- Optimization of Health Expenditure in Liver SurgeryCompletedNCT017154021 country
- Diagnostic Accuracy of Eus Fnb in Difficult to Reach LesionsCompletedNCT076215361 country
- Endoscopic Drainage of Presumed Resectable pCCA Using an Intrahepatic Plastic Stent With Retrieval StringCompletedNCT05874934Not applicable1 country
- Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic CholangiocarcinomaActive, not recruitingNCT06178588Phase 21 country
- Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCATerminatedNCT06739252Phase 21 country
- Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar CholangiocarcinomaCompletedNCT059934291 country
- NXP800 for the Treatment of Patients With Advanced or Metastatic CholangiocarcinomaTerminatedNCT06420349Phase 11 country
- Biliary Drainage Plus HAIC in Locally Advanced pCCACompletedNCT05024513Phase 21 country
- Preoperative Evaluation of Lymph Nodes of CholangiocarcinomaCompletedNCT056782182 countries
- A Study of ABC294640 Alone and in Combination With HCQ Sulfate in the Treatment of Advanced CholangiocarcinomaCompletedNCT03377179Phase 21 country
- Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract CancerTerminatedNCT045614531 country
- Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract CancerCompletedNCT05239169Phase 21 country
- Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)No longer availableNCT03414489
- Toripalimab Combined With Capecitabine as Postoperative Adjuvant Therapy for Patients With Resectable Advanced Extrahepatic Biliary Tract CancerActive, not recruitingNCT06717464Phase 21 country
- Extent of Intrahepatic Infiltration of Perihilar CholangiocarcinomaCompletedNCT063571171 country
- ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract CancerCompletedNCT01825603Phase 11 country
- REMS Combined With TAI for Unresectable HCCompletedNCT04801160Not applicable1 country
- Safety and Tumoricidal Effect of Low Dose Foscan PDT in Patients With Inoperable Bile Duct CancersCompletedNCT03003065Phase 21 country
- Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract CancersStatus unknownNCT04211168Phase 21 country
- MRI-based Clinico-radiomics Predicting Lymph Node Metastasis Status of Hilar CholangiocarcinomaStatus unknownNCT056261271 country