Intestinal Perforation clinical trials
The registry lists 36 studies for Intestinal Perforation across more than 10 countries. 5 are recruiting or about to start. 10 of them are mainly about Intestinal Perforation (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-15.
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Who runs them
All India Institute of Medical Sciences, Bhubaneswar (2) · NICHD Neonatal Research Network (2) · Manchester University NHS Foundation Trust (1) · Children's Hospitals and Clinics of Minnesota (1) · Portsmouth Hospitals NHS Trust (1) · Baylor Research Institute (1) · University Hospital of North Norway (1) · International Vaccine Institute (1)
What is being tested here
Drugs under test in Intestinal Perforation studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026Prevention of Postoperative Hernias in Emergency Surgery · Jan Kochanowski University
- Aug 2027Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) Clip · AdventHealth
Who these studies take
Of the 2 Intestinal Perforation studies recruiting now, 1 (50%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 2 (100%) | 2 (100%) |
| 30 | 2 (100%) | 2 (100%) |
| 40 | 2 (100%) | 2 (100%) |
| 50 | 2 (100%) | 2 (100%) |
| 65 | 2 (100%) | 2 (100%) |
| 75 | 2 (100%) | 2 (100%) |
| 85 | 2 (100%) | 2 (100%) |
Across all 36 studies, recruiting or not: 42% stop at 75 or younger and 42% at 65; 47% take children; 3% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 36 of 36. search them.
- Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) ClipRecruitingNCT058524571 country
- Saudi Emergency Laparotomy AuditNot yet recruitingNCT074299291 country
- Prevention of Postoperative Hernias in Emergency SurgeryRecruitingNCT068158221 country
- Necrotizing Enterocolitis and Bowel Perforation in Very Preterm Infants - Long-term Follow upNot yet recruitingNCT067575821 country
- Safety and Feasibility of Indocyanine Green Fluorescence for Intraoperative Assessment of Intestinal Perfusion in Young Infants and NeonatesNot yet recruitingNCT05734118Not applicable
- Soluble Immune Checkpoints in Intra-Abdominal InfectionsCompletedNCT076892661 country
- Enhanced Recovery Versus Standard Care After Emergency Abdominal Surgery in Patients Requiring Emergency LaparotomyCompletedNCT07650461Not applicable1 country
- Analysis of Integrated Clinical, Laboratory and Prognostic Data of Neonates With Necrotizing EnterocolitisCompletedNCT072079151 country
- The Best Care for Abdominal Emergencies StudyCompletedNCT045773391 country
- Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled TrialActive, not recruitingNCT07248761Phase 41 country
- Endosponge Vacuum Therapy (E-VAC) Registry of Intestinal Anastomotic Leaks and PerforationsCompletedNCT024779301 country
- Effect of Early Hydrocortisone on Risk of Gastrointestinal Perforations in Extremely Preterm InfantsActive, not recruitingNCT065154051 country
- Laparotomy vs. Drainage for Infants With Necrotizing EnterocolitisCompletedNCT01029353Not applicable1 country
- Impact of Abdominal Drains on the ERAS Pathway in Peptic PerforationStatus unknownNCT05368233Not applicable1 country
- Timing of Stoma Closure in NeonatesCompletedNCT047135791 country
- COMPARISON OF CONTINUOUS VERSUS INTERRUPTED-X SUTURING TECHNIQUE FOR CLOSURE OF RECTUS SHEATH IN PATIENTS UNDERGOING EMERGENCY LAPAROTOMY FOR HOLLOW VISCUS PERFORATIONStatus unknownNCT05632146Not applicable1 country
- Standardized Perioperative Management of Patients Operated With Acute Abdominal Surgery in a High-risk Emergency SettingStatus unknownNCT035496241 country
- Neokare Safety and Tolerability Assessment in Neonates With GI ProblemsStatus unknownNCT052933531 country
- Pathophysiology of Perioperative Fluid Management in Emergency LaparotomyCompletedNCT039977211 country
- TyVECO: Surveillance ProtocolStatus unknownNCT055621021 country
- Effect of Implementation of the Danish Emergency Surgery (DANAKIR) Support Network on Post-discharge Outcomes After Major Emergency Abdominal SurgeryStatus unknownNCT05442164
- ERAS vs Conventional Approach in Peptic Perforation-RCTCompletedNCT04194060Not applicable1 country
- Direct Peritoneal Resuscitation for Intra-abdominal CatastrophesStatus unknownNCT052084891 country
- The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.CompletedNCT04020939Not applicable1 country
- Therapeutic Oxygen for Gastrointestinal Atony (TOGA)CompletedNCT03386136Phase 11 country
- Intestinal Perforation in Patients Receiving an Orthtopic Liver Transplantation in the Montpellier University HospitalCompletedNCT041807351 country
- Observational Study of Surgical Treatment of Necrotizing EnterocolotisCompletedNCT012232611 country
- Early Supplementation of Enteral Microlipid With and Without Fish Oil in Premature Infants With EnterostomiesCompletedNCT01674478Phase 21 country
- Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus ArteriosusCompletedNCT01958320Phase 24 countries
- Evaluation of the Ability to Detect Bowel Gas During Laparoscopic SurgeryCompletedNCT02679118Not applicable1 country
- Ultrasound Guided Transversus Abdominis Plane(TAP) Block in Intensive Care UnitStatus unknownNCT03198338Not applicable1 country
- A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal InfectionsTerminatedNCT01110382Phase 38 countries
- IRT in Infants With Intestinal PerforationStatus unknownNCT015308281 country
- Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe SepsisCompletedNCT01784458
- Hartmann's Versus Primary Anastomosis in Left-sided Colon PerforationCompletedNCT01233713Phase 2/31 country
- Effects of Extensive Abdominal Lavage on Postoperative Inflammation Following Full Thickness Excision of Deep EndometriosisCompletedNCT00930696Phase 21 country