Hyaline Membrane Disease clinical trials
The registry lists 25 studies for Hyaline Membrane Disease across more than 10 countries. 10 are recruiting or about to start. 16 of them are mainly about Hyaline Membrane Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-14.
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Who runs them
King's College Hospital NHS Trust (1) · Leiden University Medical Center (1) · King Abdullah International Medical Research Center (1) · Loma Linda University (1) · Hôpital NOVO (1) · Mayo Clinic (1) · Mansoura University (1) · CENTOGENE GmbH Rostock (1)
What is being tested here
Drugs under test in Hyaline Membrane Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Beclomethasone | 0 | 1 | 1 |
| Betamethasone | 0 | 0 | 1 |
| Cholecalciferol | 0 | 0 | 1 |
| Zinc | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Dec 2026Comparison of the Silverman-Andersen Score and the Downes Score · Muğla Sıtkı Koçman University
- Feb 2027Early Surfactant Administration at FiO₂ >0.25 Under NIPPV for RDS in Very Preterm Infants · Jiulongpo No.1 People's Hospital
- Sep 2027ADINA vs. High Flow Nasal Cannula Comparison Study · Loma Linda University
- Oct 2027Effect of Automated Oxygen Control on Early-childhood Lung Mechanics · King's College Hospital NHS Trust
Who these studies take
Of the 3 Hyaline Membrane Disease studies recruiting now, 2 (67%) set no upper age limit and 1 (33%) stop at 75 or younger. 3 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (67%) | 2 (67%) |
| 18 | 2 (67%) | 2 (67%) |
| 30 | 2 (67%) | 2 (67%) |
| 40 | 2 (67%) | 2 (67%) |
| 50 | 2 (67%) | 2 (67%) |
| 65 | 2 (67%) | 2 (67%) |
| 75 | 2 (67%) | 2 (67%) |
| 85 | 2 (67%) | 2 (67%) |
Across all 25 studies, recruiting or not: 76% stop at 75 or younger and 76% at 65; 92% take children; 12% are for women only and 0% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 25 of 25. search them.
- Effect of Automated Oxygen Control on Early-childhood Lung MechanicsNot yet recruitingNCT078668201 country
- Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort StudyRecruitingNCT075502181 country
- The NEU - CAP TrialNot yet recruitingNCT07754032Not applicable
- Delayed Versus Immediate Cord Clamping in Preterm BirthRecruitingNCT07699666Not applicable1 country
- Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU SettingRecruitingNCT073447141 country
- ADINA vs. High Flow Nasal Cannula Comparison StudyNot yet recruitingNCT03171129Not applicable1 country
- Combined Oscillation-Volume guarantEe StudyNot yet recruitingNCT07377955Not applicable
- Comparison of the Silverman-Andersen Score and the Downes ScoreNot yet recruitingNCT071839561 country
- Heterogeneity Index in Neonatologist-performed Lung Ultrasound in Neonates Receiving Respiratory Support - a Pilot StudyNot yet recruitingNCT071175131 country
- Early Surfactant Administration at FiO₂ >0.25 Under NIPPV for RDS in Very Preterm InfantsNot yet recruitingNCT07100652Not applicable1 country
- Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants.CompletedNCT03289936Not applicable1 country
- Betamethasone and Severity of Hyaline Membrane DiseaseCompletedNCT018548401 country
- Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm NewbornsCompletedNCT05036603Not applicable1 country
- Impact of Antenatal Corticosteroid Therapy on Postnatal Surfactant Use in Preterm InfantsCompletedNCT054558791 country
- Evaluation of the Neonatal Autonomic Stress During Intubations Under Propofol in a Population of Premature Infants Under 33 w'GACompletedNCT037216401 country
- Biomarker for Hyaline Fibromatosis Syndrome (BioHFS)WithdrawnNCT031961153 countries
- Efficacy of a New Technique -"IN-REC-SUR-E"- in Preterm Neonates With RDSCompletedNCT02482766Not applicable1 country
- Anti-MERS-CoV Convalescent Plasma TherapyWithdrawnNCT02190799Phase 21 country
- The Effect of β-Carotene, Vitamin D3 and Zinc on Hyaline Membrane Disease and Feeding Intolerance in Premature NeonatesStatus unknownNCT03366584Phase 41 country
- MISurf Versus InSurE. A Comparison of Minimally Invasive Surfactant Application Techniques in Preterm InfantsTerminatedNCT01615016Phase 21 country
- Surfactant Versus Nasal Continuous Positive Airway Pressure (nCPAP) for Respiratory Distress Syndrome in the Newborn ≥ 35 Weeks of GestationTerminatedNCT01306240Phase 31 country
- Inhaled Beclomethasone to Prevent Chronic Lung DiseaseCompletedNCT00000576Phase 3
- Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)CompletedNCT00433212Phase 310 countries
- Antenatal Corticoid Therapy for Late Preterm BabiesCompletedNCT00675246Not applicable1 country
- Weaning Preterm Neonates From Nasal Continuous Positive Airway PressureCompletedNCT01093495Not applicable1 country