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Histiocytoma, Malignant Fibrous clinical trials

The registry lists 91 studies for Histiocytoma, Malignant Fibrous across more than 10 countries. 15 are recruiting or about to start. 11 of them are mainly about Histiocytoma, Malignant Fibrous (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Completed
50
Recruiting
11
Terminated
9
Status unknown
8
Active, not recruiting
6
Not yet recruiting
4

Phase

Phase 2
54
Phase 1
24
Phase 3
13

Where

United States
55
France
14
United Kingdom
14
Canada
12
Belgium
11
Germany
10

Who develops what

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Every programme with a company-led study here in the last two years, whatever its size: 2 programmes from 2 companies, 0 with this as their studies’ main aim; 0 with a live phase 3 study; 0 primary completions in the next 12 months.

Comparator & background therapies

What other companies’ phase 2+ studies give as the comparator or the background here (its leading trial sponsor and partners left out): a sign of what new drugs are measured against, not by itself the standard of care, its prescriptions or its market.

DrugLeading trial sponsor · rightsCompanies, last 5 years
DoxorubicinRecent, limited
Evidence
  • NCT06277154 · HRYZ Biotech Co. · Phase 2 · live · background · “Doxorubicin” · registered Feb 2024
  • NCT02451943 · Eli Lilly and Company · Phase 3 · background · “Doxorubicin” · registered May 2015
Hoffmann-La Roche10% of its industry studiesUS: off-patent, 14 generics marketed11 study
IfosfamideRecent, limited
Evidence
  • NCT06277154 · HRYZ Biotech Co. · Phase 2 · live · background · “Ifosfamide” · registered Feb 2024
Eli Lilly and Company50% of its industry studiesUS: off-patent, 3 generics marketed11 study
GemcitabineRecent, limited
Evidence
  • NCT06370871 · Boehringer Ingelheim · Phase 3 · comparator · “Gemcitabine” · registered Apr 2024
Eli Lilly and Company30% of its industry studiesUS: off-patent, 11 generics marketed11 study

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Programmes

“Meets, by arms” reads each study’s arms: vs its arm against the therapy’s; + X vs a combination against it; added to it plus the therapy against the therapy; studied with given together only. The next primary completion is the next phase-3 study’s when there is one.

The 2 programmes — sign in to see the whole list, free: filter by phase and aim, sort by late development, direct comparisons or the next primary completion.

Primary completion in the next 12 months (0)

Live phase 2 and 3 studies of these programmes. Primary completion is when the main measure’s data collection ends, as the registry states it (most are estimates); results come later, if they are announced.

None in the next 12 months.

Read from ClinicalTrials.gov, industry-led studies. Main aim: this is the study’s judged main condition; named, not the main aim: the sponsor names it, the study is about something else; registry mapping only: only the registry’s mapping put it here. Leading trial sponsor is the company leading the most industry studies of a drug, a measure of trial activity, not of rights. US and EU rights, and Approved: from the regulators’ records (FDA’s Drugs@FDA via openFDA; EMA’s medicines data) — the holder of a marketed or authorised original, generics and other companies’ versions; not rights elsewhere, nor approval for this condition. Phase 4 trial recorded, where neither lists it: a phase 4 study exists somewhere. Not read yet: labels by indication, exclusivity, licences, line of therapy, academic comparators, sales.

What is being tested here

Drugs under test in Histiocytoma, Malignant Fibrous studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug classes tested here Immune checkpoint inhibitors 5 open · Tyrosine kinase inhibitors (TKIs) 2 open · Alkylating agents 8 · Angiogenesis inhibitors 3

Coming up

7studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7

Who these studies take

Of the 11 Histiocytoma, Malignant Fibrous studies recruiting now, 9 (82%) set no upper age limit and 2 (18%) stop at 75 or younger. 3 (27%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 11
AgeWomenMen
100 (0%)0 (0%)
1811 (100%)11 (100%)
3011 (100%)11 (100%)
4011 (100%)11 (100%)
5011 (100%)11 (100%)
6511 (100%)11 (100%)
759 (82%)9 (82%)
859 (82%)9 (82%)

Across all 91 studies, recruiting or not: 14% stop at 75 or younger and 5% at 65; 36% take children; 1% are for women only and 0% for men only; 1% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Histiocytoma, Malignant Fibrous studies take

Of 23 phase 2 interventional studies under Histiocytoma, Malignant Fibrous, half reached primary completion within 74 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 274 mo43–94 · 23 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 91. Browse all 91 → or search them.