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Hirschsprung Disease clinical trials

The registry lists 63 studies for Hirschsprung Disease across more than 10 countries. 24 are recruiting or about to start. 46 of them are mainly about Hirschsprung Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

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Drug B with hormone therapy in advanced breast cancer

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· Enrollment: 300 → 450 participants

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Status

Completed
22
Status unknown
14
Recruiting
14
Not yet recruiting
9
Terminated
2
Active, not recruiting
1

Phase

Early Phase 1
2
Phase 2
2
Phase 4
2
Phase 3
2
Phase 1
1

Where

United States
11
China
8
France
7
United Kingdom
4
Denmark
4
Canada
4

Who runs them

Tongji Hospital (5) · Alder Hey Children's NHS Foundation Trust (3) · Weibing Tang (3) · University of Southern Denmark (3) · Assistance Publique Hopitaux De Marseille (3) · Assiut University (2) · Zunyi Medical College (2) · National Children's Hospital, Vietnam (2)

What is being tested here

Drugs under test in Hirschsprung Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Indocyanine Green112
Butyric Acid111
Saccharomyces boulardii Probiotic Supplement001
VSL#3001
Probiotic001
Lactulose001
Mineral Oil001

Coming up

2phase 3 studies under way
5studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 5

Who these studies take

Of the 14 Hirschsprung Disease studies recruiting now, 7 (50%) set no upper age limit and 6 (43%) stop at 75 or younger. 14 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (14%) take healthy volunteers.

Recruiting studies that take each age, of 14
AgeWomenMen
1013 (93%)13 (93%)
1812 (86%)12 (86%)
309 (64%)9 (64%)
409 (64%)9 (64%)
509 (64%)9 (64%)
658 (57%)8 (57%)
758 (57%)8 (57%)
858 (57%)8 (57%)

Across all 63 studies, recruiting or not: 71% stop at 75 or younger and 71% at 65; 98% take children; 0% are for women only and 0% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 50 of 63. Browse all 63 → or search them.