Glomerulonephritis clinical trials
The registry lists 115 studies for Glomerulonephritis across more than 10 countries. 32 are recruiting or about to start. 40 of them are mainly about Glomerulonephritis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 5 narrower conditions too, such as Lupus Nephritis: 895 studies, 330 open.
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Who runs them
Novartis Pharmaceuticals (7) · Assiut University (5) · Chinese University of Hong Kong (5) · Mayo Clinic (4) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Goldfinch Bio, Inc. (3) · Istanbul University (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3)
What is being tested here
Drugs under test in Glomerulonephritis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Endothelin receptor antagonists 2 open · Corticosteroids 2 open · SGLT2 inhibitors 2 open · Angiotensin receptor blockers (ARBs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10, phase 3 first
- Aug 2027A Study of Zigakibart in Adults With IgA Nephropathy · Phase 3 · Novartis Pharmaceuticals
- Dec 2026Obinutuzumab in Treatment of Fibrillary Glomerulonephritis · Mayo Clinic
- Dec 2026Correlation and Clinical Utility of Urinary Biomarker in Membranous Glomerulonephritis · Chinese University of Hong Kong
- Dec 2026The Clinical Application of Artificial Intelligence Assisted Renal Biopsy Diagnosis System. · Zhujiang Hospital
- May 2027Telitacicept for PGNMID: A Single-Arm Study · Peking University First Hospital
- Jun 2027The Effect of Daratumumab in Patients With Monoclonal Gammopathy of Renal Significance (MGRS) in Finland · Helsinki University Central Hospital
- Jun 2027Rescue of Nephrons With ALE.F02 (RENAL-F02) · Alentis Therapeutics AG
- Jul 2027Study of BHV-1400 in IgA Nephropathy · Biohaven Therapeutics Ltd.
- Nov 2027Impact of Dapagliflozin for the Regulation of Immunological Activity in Membranous Nephropathy · Centre Hospitalier Universitaire de Nice
- Nov 2027Atacicept in Multiple Glomerular Diseases · Vera Therapeutics, Inc.
Who these studies take
Of the 25 Glomerulonephritis studies recruiting now, 14 (56%) set no upper age limit and 6 (24%) stop at 75 or younger. 6 (24%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (20%) | 5 (20%) |
| 18 | 23 (92%) | 23 (92%) |
| 30 | 23 (92%) | 23 (92%) |
| 40 | 23 (92%) | 23 (92%) |
| 50 | 23 (92%) | 23 (92%) |
| 65 | 22 (88%) | 22 (88%) |
| 75 | 20 (80%) | 20 (80%) |
| 85 | 16 (64%) | 16 (64%) |
Across all 115 studies, recruiting or not: 34% stop at 75 or younger and 19% at 65; 23% take children; 0% are for women only and 0% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting3
- Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat GlomerulonephritisNov 3, 2026NCT05517980
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyNov 3, 2026NCT07902817
- China Glomerulonephritis Kidney Transplant Recipient Cohort: A Prospective Multicenter Observational StudyOct 21, 2026NCT07783737
Newly registered1
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyOct 29, 2026NCT07902817
Studies
Recruiting first, then most recently updated. Showing 50 of 115. Browse all 115 → or search them.
- Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgANRecruitingNCT07498335Phase 38 countries
- Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat GlomerulonephritisRecruitingNCT05517980Phase 21 country
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07902817Phase 31 country
- A Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07541287Phase 25 countries
- China Glomerulonephritis Kidney Transplant Recipient Cohort: A Prospective Multicenter Observational StudyRecruitingNCT077837371 country
- Correlation and Clinical Utility of Urinary Biomarker in Membranous GlomerulonephritisRecruitingNCT056888651 country
- Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal CenterEnrolling by invitationNCT010166131 country
- A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA NephropathyRecruitingNCT04557462Phase 336 countries
- The Effect of Daratumumab in Patients With Monoclonal Gammopathy of Renal Significance (MGRS) in FinlandRecruitingNCT06889948Phase 21 country
- Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country StudyRecruitingNCT07746895Phase 414 countries
- PS-002 for the Treatment of IgA Nephropathy in AdultsRecruitingNCT07182227Phase 1/22 countries
- Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.RecruitingNCT06858319Phase 39 countries
- Rescue of Nephrons With ALE.F02 (RENAL-F02)RecruitingNCT06047171Phase 210 countries
- Atacicept in Multiple Glomerular DiseasesRecruitingNCT06983028Phase 21 country
- Study of BHV-1400 in IgA NephropathyRecruitingNCT07054684Phase 12 countries
- Impact of Dapagliflozin for the Regulation of Immunological Activity in Membranous NephropathyNot yet recruitingNCT07096986Phase 21 country
- A Study to Determine if BHV-1400 is Effective and Safe in Adults With IgA NephropathyNot yet recruitingNCT07642050Phase 3
- A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A NephropathyRecruitingNCT04663204Phase 21 country
- Optimizing Referral Pathways for Patients With Hematuria and Moderate-Severe ProteinuriaNot yet recruitingNCT07431931Not applicable1 country
- Obinutuzumab in Treatment of Fibrillary GlomerulonephritisRecruitingNCT06295770Phase 21 country
- The Clinical Application of Artificial Intelligence Assisted Renal Biopsy Diagnosis System.RecruitingNCT073303621 country
- Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy?RecruitingNCT06676384Phase 41 country
- Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy.RecruitingNCT04662723Phase 41 country
- Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)RecruitingNCT068219191 country
- Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics StudyNot yet recruitingNCT06792448
- Using Renal Elastography Measurements for Evaluation of Glomerulonephritis PatientsNot yet recruitingNCT06623877Not applicable1 country
- Affection of Renal and Urinary System in IBD PatientsNot yet recruitingNCT06249243
- Assessment of the Association Between Metabolic Associated Fatty Liver Disease (MFLD) and Biopsy Proved Cases of GNRecruitingNCT061571251 country
- Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in ChildrenRecruitingNCT04654507Phase 31 country
- A Study of Rituximab in Frontline Therapy for GlomerulonephritisRecruitingNCT057619381 country
- China Kidney Patient Trials NetworkRecruitingNCT050368501 country
- Detection of Renal Fibrosis and Prediction of Kidney Function DeclineRecruitingNCT046251401 country
- Safety and Efficacy Study of OMS906 in Patients With C3G and ICGNTerminatedNCT06209736Phase 24 countries
- Effect of Ramadan Fasting on Kidney Function and Proteinuria in Patients With GlomerulonephritisCompletedNCT063270091 country
- Synergetic B-cell Immunomodulation in SLE - 2nd Study.CompletedNCT03747159Phase 31 country
- Daratumumab for Treatment of Proliferative Glomerulonephritis With Monoclonal Immune DepositsActive, not recruitingNCT05654506Phase 21 country
- KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus NephritisTerminatedNCT05938725Phase 1/21 country
- KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus NephritisTerminatedNCT06342960Phase 1/21 country
- Artificial Intelligence Model for Renal Allograft Rejection Identification, Lesion Quantification and Rejection Risk Prediction Based on Prospective Renal Transplant Pathology and Clinical Multidimensional DataActive, not recruitingNCT077415521 country
- Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA NephropathyCompletedNCT05834738Phase 26 countries
- TESTING -ON Post-Trial ObservatioNal Cohort StudyCompletedNCT054343256 countries
- Atrasentan in Patients With IgA NephropathyActive, not recruitingNCT04573478Phase 320 countries
- A Study of Mezagitamab in Adults With Primary Immunoglobulin A Nephropathy Receiving Stable Background TherapyCompletedNCT05174221Phase 111 countries
- Effect of Finerenone in Patients With Non-diabetic GlomerulonephritisCompletedNCT06835322Phase 21 country
- Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)Active, not recruitingNCT06564142Phase 333 countries
- Safety and Efficacy Study of VIS649 for IgA NephropathyCompletedNCT04287985Phase 215 countries
- A Study of Zigakibart in Adults With IgA NephropathyActive, not recruitingNCT05852938Phase 323 countries
- Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)TerminatedNCT04564339Phase 212 countries
- A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)CompletedNCT05810948Phase 21 country
- Global Kidney Patient Trials NetworkCompletedNCT043898271 country