Glaucoma, Open-Angle: all 943 studies

Page 2 of 10. Open to participants first (118), then studies with results posted, then the rest; newest registration first within each.

• Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III TrialRecruitingNCT05405868Phase 3
• Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.RecruitingNCT05401357Phase 3
• Adaptive Optics Retinal ImagingRecruitingNCT05370287Not applicable
• GATT Versus Canaloplasty (GVC)RecruitingNCT05366647Not applicable
• Use of Nanodropper vs. Standard Eyedropper in Patients With Glaucoma and Ocular HypertensionRecruitingNCT05277870Not applicable
• Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle GlaucomaRecruitingNCT05264818
• Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat TrialEnrolling by invitationNCT05159960Not applicable
• Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical ProstaglandinsRecruitingNCT05039684
• Hydrus® Microstent New Enrollment Post-Approval StudyRecruitingNCT04553523Not applicable
• Glaucoma, Visual Field Loss, and Their Association With Life Space in Older AdultsRecruitingNCT04396002
• INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma RegisterEnrolling by invitationNCT04381611
• The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma PatientsNot yet recruitingNCT04007276Phase 4
• Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot StudyRecruitingNCT03921931Not applicable
• Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy SubjectsRecruitingNCT03870230Not applicable
• Matching Glaucoma With Impaired CognitionRecruitingNCT03695224
• Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle GlaucomaRecruitingNCT03423758
• Dresden Glaucoma and Treatment Study (DGTS)RecruitingNCT02959242
• Diagnostic Innovations in Glaucoma StudyRecruitingNCT00221897
• Performance of the Travoprost Intraocular ImplantCompletedNCT06582732Phase 2Results posted
• Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Eye PressureCompletedNCT06144918Phase 2Results posted
• Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT05913232Phase 2Results posted
• A Phase 2 Double-masked Study of VVN539 in Subjects With Elevated Intraocular PressureCompletedNCT05451329Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)CompletedNCT05335122Phase 2Results posted
• Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With GlaucomaTerminatedNCT05273385Not applicableResults posted
• A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical SystemCompletedNCT05044793Results posted
• A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT05022004Phase 3Results posted
• Glaucoma Surgery Using the ViaLase Laser SystemCompletedNCT04949802Not applicableResults posted
• To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both EyesCompletedNCT04944290Phase 3Results posted
• Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular HypertensionCompletedNCT04910100Phase 2Results posted
• An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)CompletedNCT04872348Results posted
• Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients With Glaucoma Underwent Non-penetrating Glaucoma SurgeryCompletedNCT04773106Not applicableResults posted
• Study of LL-BMT1 in Patients With Elevated Intraocular PressureCompletedNCT04747808Phase 2Results posted
• Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT04742283Phase 2Results posted
• Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension.TerminatedNCT04702789Phase 4Results posted
• Study of OMNI Surgical System and iStent for Eyes With OAG (Trident)TerminatedNCT04658095Not applicableResults posted
• Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-StentCompletedNCT04629521Not applicableResults posted
• Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT04620135Phase 3Results posted
• A Post-market Study Of Use Of The OMNI® Surgical System In Open Angle GlaucomaTerminatedNCT04616573Not applicableResults posted
• Study of Exchange of Travoprost Intraocular ImplantCompletedNCT04615403Phase 2Results posted
• A Prospective, Multicenter Study of the OMNI® Surgical System in Pseudophakic Eyes With Open Angle GlaucomaTerminatedNCT04465630Not applicableResults posted
• Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04445519Phase 3Results posted
• Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle GlaucomaCompletedNCT04405245Phase 2Results posted
• CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular HypertensionCompletedNCT04360174Phase 1Results posted
• Subconjunctival Versus Direct Mitomycin C in TrabeculectomyCompletedNCT04352660Phase 4Results posted
• PRESERFLO® MicroShunt Extension StudyCompletedNCT04333433Results posted
• A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04285580Phase 3Results posted
• Safety and IOP-Lowering Effects of WB007CompletedNCT04149899Phase 1/2Results posted
• A Phase III Multinational Multicenter Investigator-Masked Randomized Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04133311Phase 3Results posted
• To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both EyesCompletedNCT04024072Phase 3Results posted
• Safety and Efficacy of Ophthalmic Phentolamine Mesylate in GlaucomaCompletedNCT03960866Phase 2Results posted
• Nailfold Capillary Blood Flow With Latanoprost BunodCompletedNCT03949244Phase 4Results posted
• Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in TrabeculectomyTerminatedNCT03875911Phase 4Results posted
• Clinical Study Comparing Two Models of a Travoprost Intraocular ImplantCompletedNCT03868124Phase 3Results posted
• Study of OMNI System in OAG (GEMINI)CompletedNCT03861169Not applicableResults posted
• Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6CompletedNCT03858894Phase 2Results posted
• Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in JapanCompletedNCT03844945Phase 2Results posted
• Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world SettingCompletedNCT03808688Phase 4Results posted
• visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated PerimetryCompletedNCT03804684Not applicableResults posted
• Performance and Safety of the ARGOS-SC Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma SurgeryCompletedNCT03756662Not applicableResults posted
• DE-117 Spectrum 5 StudyCompletedNCT03697811Phase 3Results posted
• Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT03657797Phase 2Results posted
• Long-term Safety and Performance of the ARGOS-IO Intraocular Pressure Sensor System in Subjects With Primary Open Angle Glaucoma (POAG)CompletedNCT03651336Not applicableResults posted
• Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%CompletedNCT03519386Phase 3Results posted
• H-1337 Ophthalmic Solution Phase 1/2CompletedNCT03452033Phase 1/2Results posted
• Evaluation of Safety and Efficacy of PDP-716CompletedNCT03450629Phase 3Results posted
• Educational Intervention to Adopt SLT as First-Line Glaucoma TreatmentCompletedNCT03365778Not applicableResults posted
• Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography StudyCompletedNCT03323164Phase 4Results posted
• Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular HypertensionCompletedNCT03310580Phase 2Results posted
• Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular HypertensionCompletedNCT03284853Phase 3Results posted
• Post Approval Study of the CyPass SystemTerminatedNCT03273907Not applicableResults posted
• Hydrus Microstent for Refractory Open-Angle GlaucomaCompletedNCT03267134Not applicableResults posted
• Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)CompletedNCT03257813Phase 3Results posted
• Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT03233308Phase 2Results posted
• A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel StudyCompletedNCT03216902Phase 2Results posted
• MINIject in Patients With Open Angle Glaucoma Uncontrolled by Topical Hypotensive MedicationsCompletedNCT03193736Not applicableResults posted
• Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled GlaucomaCompletedNCT03187418Not applicableResults posted
• Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle GlaucomaCompletedNCT03131167Phase 1Results posted
• A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHTCompletedNCT02981446Phase 3Results posted
• Safety and Effectiveness of the Sight Sciences VISCO™360 Versus SLT in Primary Open Angle GlaucomaTerminatedNCT02928289Not applicableResults posted
• Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHTCompletedNCT02914509Phase 3Results posted
• Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic SolutionCompletedNCT02874846Phase 2Results posted
• Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAGCompletedNCT02829996Phase 2Results posted
• Ahmed Glaucoma Valve Surgery With Mitomycin-CCompletedNCT02805257Phase 2Results posted
• Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular HypertensionTerminatedNCT02801617Phase 3Results posted
• Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT02796560Phase 4Results posted
• Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic SolutionCompletedNCT02754596Phase 2Results posted
• The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion PressureCompletedNCT02754570Not applicableResults posted
• A Three Part Study of MGV354 in Ocular Hypertension or GlaucomaCompletedNCT02743780Phase 1/2Results posted
• A Study to Evaluate Efficacy and Safety of a Fixed Combination Ocular Insert in Participants With Open-angle Glaucoma or Ocular HypertensionCompletedNCT02742649Phase 1/2Results posted
• Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®TerminatedNCT02730871Phase 4Results posted
• A Study to Assess Long-Term Safety of the CyPass Micro-Stent in Patients Completing the COMPASS TrialCompletedNCT02700984Not applicableResults posted
• Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular HypertensionCompletedNCT02674854Phase 3Results posted
• A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02636946Phase 3Results posted
• 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for GlaucomaCompletedNCT02628223Not applicableResults posted
• Analysis of the Eye in Patients With Primary Open-Angle Glaucoma and a Visual Field Defect in One EyeCompletedNCT02622191Not applicableResults posted
• Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT02558400Phase 3Results posted
• Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular HypertensionCompletedNCT02558374Phase 3Results posted
• An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular InsertCompletedNCT02537015Phase 2Results posted
• Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both EyesCompletedNCT02512042Phase 3Results posted
• Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02507687Phase 3Results posted

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