Endodermal Sinus Tumor clinical trials

The registry lists 51 studies for Endodermal Sinus Tumor across more than 10 countries. 7 are recruiting or about to start. 2 of them are mainly about Endodermal Sinus Tumor (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-13.

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Status

Completed: 37
Recruiting: 6
Active, not recruiting: 4
Status unknown: 2
Not yet recruiting: 1
Terminated: 1

Phase

Phase 2: 20
Phase 3: 14
Phase 1: 14

Where

United States: 38
United Kingdom: 10
France: 5
Netherlands: 5
Germany: 5
Australia: 5

Who runs them

Fred Hutchinson Cancer Center (7) · Children's Oncology Group (5) · Memorial Sloan Kettering Cancer Center (5) · National Cancer Institute (NCI) (4) · Baylor College of Medicine (4) · European Organisation for Research and Treatment of Cancer - EORTC (4) · Medical Research Council (2) · Seattle Children's Hospital (2)

What is being tested here

Drugs under test in Endodermal Sinus Tumor studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Cisplatin	1	3	6
Etoposide	1	4	6
Carboplatin	1	2	5
Bleomycin	1	2	2
Paclitaxel	0	3	9
Ifosfamide	0	2	8
Filgrastim	0	0	3
Pegfilgrastim	0	0	2
Nivolumab	0	0	1
Etoposide phosphate	0	1	1

Drug classes tested here Antimitotic agents 10 · Alkylating agents 8

Coming up

2phase 3 studies under way

4studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 4, phase 3 first

Jun 2027Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors · Phase 3 · Children's Oncology Group
Jun 2027Molecular Epidemiology of Pediatric Germ Cell Tumors · Children's Oncology Group
Jul 2027Agnostic Therapy in Rare Solid Tumors · Instituto do Cancer do Estado de São Paulo
Aug 2027Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors · Baylor College of Medicine

Who these studies take

Of the 6 Endodermal Sinus Tumor studies recruiting now, 3 (50%) set no upper age limit and 3 (50%) stop at 75 or younger. 5 (83%) take children under 18. 0 (0%) are for women only and 1 (17%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 6
Age	Women	Men
10	5 (83%)	5 (83%)
18	5 (83%)	6 (100%)
30	2 (33%)	3 (50%)
40	2 (33%)	3 (50%)
50	2 (33%)	3 (50%)
65	2 (33%)	3 (50%)
75	2 (33%)	3 (50%)
85	2 (33%)	3 (50%)

Across all 51 studies, recruiting or not: 41% stop at 75 or younger and 33% at 65; 71% take children; 0% are for women only and 24% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 50 of 51. Browse all 51 → or search them.