CompletedNCT00439114Updated Feb 23, 2007

Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze

An observational study in Corneal Opacity, sponsored by Baskent University. Completed at 1 site in Turkey. Open to participants aged 18 Years to 71 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-02-23.

Sponsored by Baskent University · Observational

Study type: Observational
Model: Defined population
Time perspective: Other
Enrollment: 40
Ages: 18 Years to 71 Years
Sex: All

Study summary

This study is planned to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. Corneal haze is graded with slit-lamp by a single examiner. Ultrasonic and Orbscan II pachymetry measurements are obtained. Paired t and Kruskal-Wallis tests are used to evaluate the difference between ultrasonic and Orbscan pachymetry measurements. Correlation of the two methods and haze grade is determined with Kendall's tau-b correlation analysis.

Read the detailed description

We planned this study to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. In this institutional based, prospective, controlled clinical trial subjects with corneal haze not related to surgery are included. Normal eyes are used as control group to calculate the customized acoustic factor. Corneal haze is graded with slit-lamp by a single examiner. Ultrasonic and Orbscan II pachymetry measurements are obtained by one technician each masked to the other measurement. Paired t and Kruskal-Wallis tests are used to evaluate the difference between ultrasonic and Orbscan pachymetry measurements. Correlation of the two methods and haze grade is determined with Kendall's tau-b correlation analysis. According to the results of the study, we will determine which method is accurate in subjects with corneal haze.

Conditions studied

Corneal Opacity

Browse trials for

Keywords

Corneal topography, corneal opacity, keratitis, trachoma

In context

Corneal Opacity

37 studies on the registry are indexed under Corneal Opacity; 5 are open to participants now.

This study's enrollment of 40 is below the median of 45 across 14 observational studies indexed under Corneal Opacity.

Browse Corneal Opacity studies →

Lead sponsor

Baskent University is the lead sponsor of 209 studies on the registry; 35 are open to participants now.

Browse Baskent University studies →

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years to 71 Years
Sexes eligible: All
Accepts healthy volunteers: Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Patients with significant corneal haze on slit-lamp are included in the study group. 50 eyes of 50 age-matched patients with normal eye and clear cornea are included in the control group. Only one eye of each subject is included.

Exclusion criteria

Exclusion Criteria:

Exclusion criteria to participate in the study are previous ocular surgery, history of contact lens use, glaucoma, and topical ocular medication use, excluding artificial tears.

Study design

Observational model: Defined population
Time perspective: Other
Enrollment: 40 participants

Study locations

1 site

Baskent University, Faculty of Medicine, Adana Hospital
Adana, 01250, Turkey

References and documents

Publications

Boscia F, La Tegola MG, Alessio G, Sborgia C. Accuracy of Orbscan optical pachymetry in corneas with haze. J Cataract Refract Surg. 2002 Feb;28(2):253-8. doi: 10.1016/s0886-3350(01)01162-2. PubMed 11821206 ↗
Iskander NG, Anderson Penno E, Peters NT, Gimbel HV, Ferensowicz M. Accuracy of Orbscan pachymetry measurements and DHG ultrasound pachymetry in primary laser in situ keratomileusis and LASIK enhancement procedures. J Cataract Refract Surg. 2001 May;27(5):681-5. doi: 10.1016/s0886-3350(01)00820-3. PubMed 11377895 ↗
Altan-Yaycioglu R, Pelit A, Akova YA. Comparison of ultrasonic pachymetry with Orbscan in corneal haze. Graefes Arch Clin Exp Ophthalmol. 2007 Dec;245(12):1759-63. doi: 10.1007/s00417-007-0578-5. Epub 2007 Jun 22. PubMed 17583820 ↗

Timeline

Tracking since Sep 25, 2026

Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Jul 2005 and a completion of Jun 2006. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered: Feb 21, 2007
First posted: Feb 23, 2007
Start: Jul 2005
Completion: Jun 2006
Last update: Feb 23, 2007

What these dates mean

Start.: When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Completion.: When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.

No changes since tracking began. The registry record was last updated on Feb 23, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT00439114
Lead sponsor: Baskent University
First posted: Feb 23, 2007
Start date: Jul 2005
Completion: Jun 2006
Last update: Feb 23, 2007

Study contacts

Rana Altan-Yaycioglu, M.D.

principal investigator · Baskent University, Faculty of Medicine, Department of Ophthalmology

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2007. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Corneal Opacity →

Other studies from this sponsor

Baskent University →

Start the discussion