Colorectal Neoplasms, Hereditary Nonpolyposis: all 141 studies
Page 1 of 2. Open to participants first (60), then studies with results posted, then the rest; newest registration first within each.
- Protocol for Non-invasive Gynaecological Surveillance in Lynch SyndromeNot yet recruitingNCT07877779
- A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or RectumRecruitingNCT07811193Phase 2
- Preventive Dendritic Cell Vaccination for Lynch Syndrome CarriersNot yet recruitingNCT07609901Phase 3
- Periodontal Disease in Patients With Lynch SyndromeNot yet recruitingNCT07600710
- A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American FamiliesNot yet recruitingNCT07542405Not applicable
- Population Based Germline Testing for Early Detection and Prevention of CancerRecruitingNCT07498829Not applicable
- Small Bowel Capsule Endoscopy in Lynch SyndromeRecruitingNCT07472686
- Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease DetectionRecruitingNCT07450612
- Evaluation of Capsule Colonoscopy in Patients With Lynch SyndromeNot yet recruitingNCT07445828
- Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of CancerRecruitingNCT07436312Not applicable
- Preventive Dendritic Cell Vaccination for Lynch SyndromeNot yet recruitingNCT07412197Phase 1/2
- Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural EnvironmentEnrolling by invitationNCT07381985Not applicable
- Study Aiming to Test Whether Non-invasive Liquid Biopsies Can Safely Reduce Invasive Surveillance Methods in Lynch SyndromeNot yet recruitingNCT07360834Not applicable
- Overcoming Barriers to Uptake of Cascade ScreeningNot yet recruitingNCT07304063Not applicable
- Menstrual Cup for Early Endometrial Cancer Detection in Lynch SyndromeRecruitingNCT07220239Not applicable
- A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE CapsuleRecruitingNCT07219537Not applicable
- Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch SyndromeRecruitingNCT07201012Not applicable
- Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health QuestionnaireRecruitingNCT07194551Not applicable
- First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome CarriersRecruitingNCT07163403Phase 1
- Clinical Validation of Sophia Genetics AssayNot yet recruitingNCT07160010
- Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch SyndromeRecruitingNCT07106359Not applicable
- The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary TractRecruitingNCT07077447
- Lynch Syndrome in Colorectal Cancer SurgeryNot yet recruitingNCT06990633
- Smart Measurement of Circulating Tumor DNARecruitingNCT06989814Not applicable
- Patient Centered Clinical Decision Support for Hereditary Cancer SyndromesEnrolling by invitationNCT06914726Not applicable
- FITting Non-invasive Tests in Lynch Syndrome SurveillanceRecruitingNCT06898996Not applicable
- Predictive Value of PREMM5, MMRpredict, and Universal Tumor Screening for Lynch Syndrome in VietnamNot yet recruitingNCT06863038
- DYNAMICS-LYNCH：DNA Methylation Analysis in Stool for Screening of Lynch Syndrome-Associated Colorectal CancerNot yet recruitingNCT06772844
- CfDNA in Hereditary And High-risk Malignancies 2RecruitingNCT06726642
- Video Capsule Examination in Patients With Lynch SyndromeRecruitingNCT06712095Not applicable
- Lynch Syndrome X-Talk of Enteral Mucosa With Immune SystemRecruitingNCT06708429
- Lynch Syndrome Integrative Epidemiology and GeneticsRecruitingNCT06582914
- Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsRecruitingNCT06523582
- EC_ItaLynch: Mainstreaming the Diagnosis of Lynch SyndromeNot yet recruitingNCT06501417
- PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition SyndromeRecruitingNCT06447961
- Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study)RecruitingNCT06218433Not applicable
- Inherited Cancer Early Diagnosis (ICED) StudyRecruitingNCT06163365
- CAD-EYE System for the Detection of Neoplastic Lesions in Patients With Lynch SyndromeRecruitingNCT05963191Not applicable
- Perception About Benefits and Risks Related to Combined Hormonal Contraceptives Use in Patients With Lynch SyndromeNot yet recruitingNCT05909410
- Videocapsule Endoscopy in Lynch SyndromeRecruitingNCT05704010Not applicable
- Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal CancerRecruitingNCT05495776
- A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch SyndromeRecruitingNCT05411718Phase 2
- Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome PatientsRecruitingNCT05410977
- Prostate Cancer Genetic Risk Evaluation and Screening StudyRecruitingNCT05129605
- Mesalamine for Colorectal Cancer Prevention Program in Lynch SyndromeRecruitingNCT04920149Phase 2
- DNA Adductomics for Colorectal Cancer InvestigationRecruitingNCT04865601
- PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome PatientsRecruitingNCT04711434Phase 3
- Identifying and Caring for Individuals With Inherited Cancer SyndromeRecruitingNCT04494945Not applicable
- Registry of Subjects at Risk of Pancreatic CancerRecruitingNCT04095195
- Men at High Genetic Risk for Prostate CancerRecruitingNCT03805919
- Liquid Biopsy Evaluation and Repository Development at Princess MargaretRecruitingNCT03702309
- The GEOLynch Cohort StudyRecruitingNCT03303833
- Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in SwitzerlandRecruitingNCT03124212
- Familial Investigations of Childhood Cancer PredispositionRecruitingNCT03050268
- Pancreas Registry and High Risk RegistryRecruitingNCT02775461
- Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline MutationsRecruitingNCT02705846
- Finding the Best Dose of Aspirin to Prevent Lynch Syndrome CancersNot yet recruitingNCT02497820Phase 3
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT02012699
- The Cancer of the Pancreas Screening-5 CAPS5)StudyRecruitingNCT02000089Phase 3
- Familial Colorectal Cancer Registry in HispanicsRecruitingNCT00927680
- Using Visual Arrays to Support Understanding of Genetic RiskCompletedNCT06994832Not applicableResults posted
- PeLear CCC: Proyecto Latino Contra Cancer ColorrectalCompletedNCT06426927Not applicableResults posted
- Colonoscopy Check-up in People With Lynch SyndromeCompletedNCT06126120Results posted
- Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility StudyCompletedNCT04978350Not applicableResults posted
- Pediatric Reporting of Adult-Onset Genomic ResultsCompletedNCT03832985Early Phase 1Results posted
- Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial ColectomyTerminatedNCT03631641Phase 2Results posted
- Cancer Health Assessments Reaching ManyCompletedNCT03426878Not applicableResults posted
- Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch RepairActive, not recruitingNCT02912559Phase 3Results posted
- Educational CD-ROM Compared With Standard Informed Consent for Patients With Colorectal Cancer or a Family History of Colorectal CancerCompletedNCT00450424Not applicableResults posted
- Liquid Biopsy Biomarkers for Endoscopic Surveillance in Lynch SyndromeCompletedNCT07838246
- The Yield of Artificial Intelligence (GI Genius) in Lynch Syndrome - A Randomized Tandem-colonoscopy TrialCompletedNCT06654128Not applicable
- The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel TherapeuticsActive, not recruitingNCT05692596
- Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) InterventionActive, not recruitingNCT05677048Not applicable
- Testing a Combination of Vaccines for Cancer Prevention in Lynch SyndromeActive, not recruitingNCT05419011Phase 2
- Frequency of Endometrial Cancer Precursors Associated with Lynch SyndromeCompletedNCT05257057
- Cancer Preventive Vaccine Nous-209 for Lynch Syndrome PatientsActive, not recruitingNCT05078866Phase 1/2
- Evaluation of ArTificial Intelligence System (Gi-Genius) for adenoMa dEtection in Lynch Syndrome.Status unknownNCT04909671Not applicable
- Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial CancerTerminatedNCT04906382Early Phase 1
- Faecal Microbiota Characterization in Lynch Syndrome (LS) Patients With or Without Colorectal NeoplasiaStatus unknownNCT04791644
- Evaluating the Cologuard Test for Use in Lynch SyndromeWithdrawnNCT04778566
- Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair MutationStatus unknownNCT04516083
- Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch SyndromeTerminatedNCT04508764Not applicable
- Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI StudyWithdrawnNCT04500548Phase 1
- Predictive Factor Study of the Occurrence of Endometrial Cancer in Patients With Lynch SyndromeCompletedNCT04452266
- Scalable Communication Modalities for Returning Genetic Research ResultsCompletedNCT04407611Not applicable
- Atorvastatin ± Aspirin in Lynch Syndrome SyndromeCompletedNCT04379999Early Phase 1
- Cell-free DNA in Hereditary And High-Risk Malignancies 1Active, not recruitingNCT04261972
- Direct Information to At-risk RelativesActive, not recruitingNCT04197856Not applicable
- Family History Study on Cancer RiskActive, not recruitingNCT04145388Not applicable
- Trial to Compare eConsent With Standard Consent Among Prospective Biobank ParticipantsCompletedNCT04131062Not applicable
- Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome FamiliesActive, not recruitingNCT04125914Not applicable
- Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE)Active, not recruitingNCT03831698Phase 2
- MSI in Circulatory DNA of Endometrial CancerStatus unknownNCT03744962
- Cycling in Preventing Colorectal Cancer in Participants With Lynch SyndromeCompletedNCT03495674Not applicable
- Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized CareCompletedNCT03460483Not applicable
- Genetic Risk: Whether, When, and How to Tell AdolescentsCompletedNCT03421327
- Linked Color Imaging Versus High-definition White Light Endoscopy for the Detection of Polyps in Patients With Lynch Syndrome (LCI-LYNCH)CompletedNCT03344289Not applicable
- Risk-Reducing Surgeries for Hereditary Ovarian CancerStatus unknownNCT03294343Not applicable
- Study of Universal Screening for Lynch Syndrome in Chinese Patients of Endometrial CancerStatus unknownNCT03291106
- Mesalamine for Colorectal Cancer Prevention Program in Lynch SyndromeTerminatedNCT03070574Phase 2