Cocaine-Related Disorders: all 419 studies

Page 2 of 5. Open to participants first (12), then studies with results posted, then the rest; newest registration first within each.

• Vigabatrin for Treatment of Cocaine DependenceCompletedNCT00611130Phase 2Results posted
• Galantamine Effects on Cognitive Function in Abstinent Cocaine UsersCompletedNCT00606801Not applicableResults posted
• Modafinil, Sleep, and Cognition in Cocaine DependenceCompletedNCT00582491Not applicableResults posted
• Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained PatientsCompletedNCT00577005Phase 2Results posted
• A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine AddictionCompletedNCT00567814Not applicableResults posted
• Efficacy of Varenicline in Methadone-Stabilized Cocaine UsersCompletedNCT00567320Not applicableResults posted
• Chantix for Treating Cocaine DependenceCompletedNCT00567008Phase 2Results posted
• Cocaine Withdrawal and Pharmacotherapy ResponseCompletedNCT00566969Not applicableResults posted
• Study of Adderall-XR for the Treatment of Adult Attention Deficit Hyperactivity Disorder and Cocaine DependenceCompletedNCT00553319Phase 2/3Results posted
• The Effect of Yohimbine on Cocaine Cue ReactivityCompletedNCT00535002Phase 2Results posted
• Use of Donepezil for Treatment of Cocaine DependenceCompletedNCT00467389Phase 2Results posted
• A Placebo-Controlled Study of Mixed Amphetamine Salts and Topiramate for the Treatment of Cocaine DependenceCompletedNCT00421603Phase 2Results posted
• Disulfiram for Cocaine AbuseCompletedNCT00395850Phase 2Results posted
• Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine DependenceCompletedNCT00385801Phase 2Results posted
• Pilot Trial of Acamprosate for the Treatment of Cocaine DependenceCompletedNCT00385268Phase 2Results posted
• Imaging the Neurobiology of a Behavioral Treatment for Cocaine DependenceCompletedNCT00376558Not applicableResults posted
• Effects of Aripiprazole on Cocaine Craving and Self-AdministrationCompletedNCT00373880Phase 2Results posted
• Modafinil Treatment for Cocaine Dependence and HIV High-Risk BehaviorCompletedNCT00368290Phase 2Results posted
• CBT With Disulfiram and Contingency ManagementCompletedNCT00350870Phase 1Results posted
• Efficacy of Mirtazapine in Depressed Cocaine Dependent SubjectsCompletedNCT00322309Phase 2Results posted
• Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine DependencyCompletedNCT00280293Phase 4Results posted
• The Therapeutic Workplace Initiation StudyCompletedNCT00249470Not applicableResults posted
• Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From DepressionCompletedNCT00249444Phase 2Results posted
• Prazosin for ETOH or Cocaine CravingTerminatedNCT00240227Not applicableResults posted
• Valproate Efficacy in Cocaine-Bipolar ComorbidityCompletedNCT00240110Phase 1/2Results posted
• Therapeutic Substance Abuse Treatment in Pregnancy - 1CompletedNCT00227903Phase 2Results posted
• Trial of Citicoline Therapy in Patients With Mania or Hypomania and Cocaine Abuse/DependenceCompletedNCT00223236Phase 3Results posted
• Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD)CompletedNCT00218543Phase 2Results posted
• Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1CompletedNCT00218491Phase 2Results posted
• Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1CompletedNCT00218387Phase 2Results posted
• Progesterone for the Treatment of Cocaine Dependence - 1CompletedNCT00218257Not applicableResults posted
• Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent IndividualsCompletedNCT00218062Phase 2Results posted
• Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8TerminatedNCT00218036Phase 2Results posted
• Medications for Stopping Cocaine Dependence and Preventing RelapseCompletedNCT00218023Phase 2Results posted
• Topiramate for Alcohol and Cocaine DependenceCompletedNCT00167245Phase 2Results posted
• Employment-based Reinforcement of Naltrexone Ingestion and AbstinenceCompletedNCT00149669Not applicableResults posted
• Pharmacogenetics of Disulfiram for CocaineCompletedNCT00149630Phase 2Results posted
• Modafinil and Naltrexone to Reduce Cocaine and Alcohol DependenceCompletedNCT00142818Phase 2Results posted
• Effectiveness of Memantine in Treating Cocaine-Dependent Individuals - 2CompletedNCT00134901Phase 2Results posted
• Modafinil Treatment for Cocaine-Dependent IndividualsCompletedNCT00129285Phase 2Results posted
• Comparing Efficacy & Safety Of TNX-1300 To Placebo With UC For Treatment Of Acute Cocaine Intoxication In ED Subjects (CATALYST)TerminatedNCT06045793Phase 2
• Low-Intensity Focused Ultrasound for Cocaine Use DisorderCompletedNCT05857852Not applicable
• Effect of rTMS on Neurotrophines Levels in CUDStatus unknownNCT05824221Not applicable
• Clavulanic Acid for the Treatment of Cocaine Use DisorderActive, not recruitingNCT05562349Phase 2
• Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)CompletedNCT05262270Phase 2
• TDCS to Reduce Craving in Cocaine Addiction- Phase 2 StudyCompletedNCT04994821Phase 2
• AAV8-hCocH for Cocaine Use DisorderActive, not recruitingNCT04884594Phase 1
• Pioglitazone as an Adjunct to Cognitive-Behavioral Therapy for Cocaine Relapse PreventionCompletedNCT04843046Phase 2
• sTMS for Substance Use-disordered VeteransCompletedNCT04336293Not applicable
• Use of Intranasal Oxytocin During Detoxification of Crack CocaineCompletedNCT04306354Phase 1/2
• Benefits of Therapy With Virtual Reality Exposure in the Treatment of Cocaine Use DisordersStatus unknownNCT04280900Not applicable
• Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic AcidCompletedNCT03986762Phase 1
• The Effect of Self-Forgiveness on Self-Stigma in Addiction.CompletedNCT03971097Not applicable
• Computerized Exercise to Alter Stimulant Approach ResponsesStatus unknownNCT03902405Not applicable
• TDCS for Cocaine Addiction CravingCompletedNCT03833583Not applicable
• Neurobehavioral Measurement of Substance Users in Outpatient Treatment SettingCompletedNCT03662529Not applicable
• Brain Mechanisms in Young AdultsCompletedNCT03606473Early Phase 1
• Evaluation of N-Acetylcysteine Efficacy to Reduce the Craving and to Prolong Abstinence Time of Coca PasteCompletedNCT03556371Phase 2
• Longitudinal Assessment of Functional Connectivity in Treatment Engaged Cocaine UsersCompletedNCT03554928
• Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients with Cocaine AddictionTerminatedNCT03423667Phase 2
• Cocaine Use Disorder and Cortical DopamineCompletedNCT03349606Early Phase 1
• Transcranial Magnetic Stimulation for Cocaine AddictionStatus unknownNCT03333460Not applicable
• Rebalancing the Serotonergic System in Cocaine DependenceWithdrawnNCT03266939Phase 1
• 10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine DependenceCompletedNCT03238859Phase 2
• Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use DisorderTerminatedNCT03143543Phase 1
• Methylphenidate for Cocaine DependenceWithdrawnNCT03090269Phase 2
• Effects of tDCS on Craving, Relapse and Cognitive Functions Among Patients With Cocaine Use DisorderCompletedNCT03025321Not applicable
• Effect of N-acetylcysteine on Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.Status unknownNCT03018236Phase 4
• Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine DependenceCompletedNCT02994875Early Phase 1
• Treatment With Transcranial Magnetic Stimulation for Cocaine Addiction: Clinical Response and Functional Connectivity.Status unknownNCT02986438Not applicable
• The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol CuesCompletedNCT02939352Early Phase 1
• Effects of Glucocorticoids on Craving During Detoxification Treatment of Heroin and/or StimulantsTerminatedNCT02935101Phase 2
• Towards Detecting Cocaine Use Using Smartwatches in the NIDA Clinical Trials NetworkCompletedNCT02915341
• Deep Brain Stimulation of the Sub-Thalamic Nucleus to Treat Severe and Treatment-resistant Cocaine Addiction.Status unknownNCT02892851Not applicable
• Conflict Between Maternal Autonomy and Child Health in Substance-useCompletedNCT02797990
• Dexamphetamine Sustained Release Pharmacokinetics and Clinical Validation of Dried Blood SpotsCompletedNCT02768441Early Phase 1
• Neurobiological Adaptations and Pharmacological Interventions in Cocaine AddictionCompletedNCT02626494Phase 4
• Cannabidiol and Cocaine Craving/DependenceCompletedNCT02559167Phase 2
• Complementary Combination Therapy for Cocaine DependenceCompletedNCT02538744Phase 1
• Predicting Relapse After Cocaine Inpatient CessationCompletedNCT02416050
• Study to Assess Potential Interactions Between Intravenous Cocaine and Oral LorcaserinCompletedNCT02393599Phase 1
• GLP-1 Agonism for Blocking Cocaine Euphoria and Self-AdministrationCompletedNCT02302976Phase 1
• Topiramate-Phentermine Combinations for Cocaine DependenceCompletedNCT02239913Phase 1
• Dopamine Rhythms in Health and AddictionWithdrawnNCT02233829Early Phase 1
• PET Imaging in Cocaine Self AdministrationCompletedNCT02181491Not applicable
• A PET Exploration of the Mechanism of Action of Dopamine Beta-hydroxylase Inhibition in Cocaine AddictsWithdrawnNCT02134002Phase 4
• Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRSCompletedNCT02124941Phase 1
• Ovarian Hormones and Stress Induced Drug CravingCompletedNCT02098434Not applicable
• Hippocampal Neurogenesis in Human SubjectsCompletedNCT02028273
• Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in HumansCompletedNCT02018263Phase 1
• A Study of Baclofen ERWithdrawnNCT02003664Phase 2
• Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine DependenceCompletedNCT01984177
• Establishing and Eliminating Cue-drug Associations in Human Cocaine AddictionTerminatedNCT01978457Phase 1
• Impulsivity and Stimulant AdministrationCompletedNCT01978431Phase 1
• Neuropsychological Rehabilitation on Cocaine/Crack DependentsStatus unknownNCT01914835Not applicable
• Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent SubjectsCompletedNCT01887366Phase 2
• A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine AbuseCompletedNCT01846481Phase 2
• Exercise as an Adjunctive Treatment for Cocaine Dependent PatientsCompletedNCT01832649Not applicable
• Treating Cocaine Abuse: A Behavioral ApproachStatus unknownNCT01822327Phase 2
• Progesterone and Atomoxetine for Cocaine CessationWithdrawnNCT01741376Not applicable

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