Chronic Urticaria: all 194 studies

Page 1 of 2. Open to participants first (46), then studies with results posted, then the rest; newest registration first within each.

• Remibrutinib in Real-world Clinical Practice - a South Korea Sub-StudyNot yet recruitingNCT07920315
• A Trial to Evaluate the Efficacy and Safety of AK139 in Participants With Chronic Spontaneous UrticariaNot yet recruitingNCT07875426Phase 2
• Apremilast Added to Antihistamines in Chronic UrticariaEnrolling by invitationNCT07850843Phase 2
• A Phase 2 Study of MG-K10 in Chronic Spontaneous UrticariaNot yet recruitingNCT07838727Phase 2
• Characteristics and Management of Patients With Severe Chronic Spontaneous and/or Inducible Urticaria Refractory to Optimized Omalizumab Treatment: A French Multicenter Observational Study.RecruitingNCT07833696
• Investigation of a Remibrutinib- and Omalizumab-based Treatment Algorithm in Adult Patients With Chronic Spontaneous Urticaria Inadequately Controlled by H1-antihistamines Within 24 WeeksRecruitingNCT07816328Phase 3
• A Study to Assess the Efficacy and Safety of THB335 in Adults With Chronic Spontaneous Urticaria (CSU)RecruitingNCT07766499Phase 2
• Mediterranean and Low-Histamine Diets for Pediatric Chronic Spontaneous UrticariaRecruitingNCT07765979Not applicable
• A Study of Efficacy and Safety of TLL-018 in CSU Participants With Inadequate Response to 2nd-generation H1-AHsNot yet recruitingNCT07764003Phase 2
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics and Clinical Activity of BBT001 Following Intravenous Administration in Participants With Chronic Spontaneous Urticaria (CSU)RecruitingNCT07717905Phase 1/2
• Phase Ib, Randomized, Double-blind, Placebo-Controlled, Dose-Escalation Study of Alpha-0261 Tablets to Assess Safety and Tolerability in Patients With Chronic Spontaneous Urcaria (Part 1) and Food Effect in Healthy Adults (Part 2).Not yet recruitingNCT07684560Phase 1
• A Phase Ib/IIa Study Assessing the Rapid Onset Characteristics of TLL-018 for Moderate-to-Severe CSU With Inadequate Response to Second-Generation H1 AntihistaminesNot yet recruitingNCT07665996Phase 1/2
• Remibrutinib in Real-world Clinical Practice - a Germany Sub-study (REASSERT)RecruitingNCT07642557
• Pseudoallergen-Free and Low-Histamine Diet in Adolescents With Chronic Spontaneous UrticariaEnrolling by invitationNCT07632040Not applicable
• A Clinical Trial of HRS-3095 in Patients With Chronic Spontaneous UrticariaNot yet recruitingNCT07613866Phase 2
• A Prospective, Single-centre, Observational Cohort Study on the Efficacy and Safety of Bacterial Lysate (OM-85) in Combination With Antihistamines for the Treatment of Chronic Spontaneous Urticaria (CSU)Not yet recruitingNCT07557888
• A Study of MG-K10 in Chronic Spontaneous UrticariaNot yet recruitingNCT07546487Phase 3
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy AdultsRecruitingNCT07540910Phase 1
• Autologous Whole Blood Therapy in Chronic Idiopathic Urticaria Patients.Not yet recruitingNCT07486583Phase 3
• Effects of Diet and Oxidative Stress on Disease Severity and Response to Omalizumab in Chronic Spontaneous UrticariaEnrolling by invitationNCT07431658
• ROLL'YN-OMA: an Observational Study in Patients Treated by Omlyclo®, an Omalizumab BiosimilarRecruitingNCT07425639
• Phase 2 Study of Lesigercept in Adult Patients With Chronic Spontaneous Urticaria Who Are Inadequately Controlled by H1-AntihistaminesRecruitingNCT07415551Phase 2
• A Real-world Study of Remibrutinib in Chronic Spontaneous Urticaria PatientsRecruitingNCT07408219
• Trial of JYB1904 Injection in Adult Patients With Chronic Spontaneous Urticaria.RecruitingNCT07402213Phase 3
• Study of the Efficacy and Safety of ICP-332 in Participants With Chronic Spontaneous UrticariaRecruitingNCT07378527Phase 2/3
• Remibrutinib in Real-world Clinical Practice - a US Sub-studyRecruitingNCT07358780
• Remibrutinib in Real-world Clinical PracticeRecruitingNCT07358364
• Analysis of the Role of IgE Proteoforms in Health and DiseaseRecruitingNCT07328178
• Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous UrticariaEnrolling by invitationNCT07256392Phase 3
• A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.RecruitingNCT07219615Phase 2
• Study of CM512 Injection in Subjects With Chronic Spontaneous Urticaria(CSU)RecruitingNCT07166211Phase 2
• SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)RecruitingNCT07021495
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple-Ascending Doses of Tacabrutideg (BGB-16673) in Adults With Chronic Spontaneous Urticaria and in Healthy ParticipantsRecruitingNCT07005713Phase 1
• An Outpatient Study of the Efficacy of ARS-2 in Patients With Chronic Spontaneous UrticariaRecruitingNCT06927999Phase 2
• Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic UrticariaRecruitingNCT06865651Phase 2
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HS-10561 Capsule in Healthy Chinese Adults and Patients With Chronic Spontaneous Urticaria.Not yet recruitingNCT06864507Phase 1/2
• Treatment Options for Chronic UrticariaNot yet recruitingNCT06816784Phase 2
• Trial of JYB1904 in Chronic Spontaneous Urticaria.RecruitingNCT06509334Phase 2
• A Study to Explore the Efficacy and Safety of HWH486 in Adults With Chronic Spontaneous UrticariaRecruitingNCT06295302Phase 2
• Efficacy and Safety of Histamine Human Immunoglobulin in the Treatment of Chronic Spontaneous Urticaria (CSU)Not yet recruitingNCT06250400Phase 4
• Assessment of Serum Levels of Adenosine Deaminase and Immunoglobulin E in Patients With Chronic Spontaneous UrticariaNot yet recruitingNCT05992987
• Extending Omalizumab Treatment Intervals in Patients With Chronic Spontaneous UrticariaRecruitingNCT05916937Phase 4
• Global Managed Access Program Cohort for Remibrutinib in Adult Patients With Chronic Spontaneous UrticariaAvailableNCT05170724
• Compassionate Use or Expanded Access of DupilumabAvailableNCT04776694
• Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of UB-221 in Healthy VolunteersNot yet recruitingNCT04404023Phase 1
• Evaluating the Safety and Tolerability and Determining the PK and PD of Single Dose UB-221 in Chronic Spontaneous UrticariaNot yet recruitingNCT04175704Phase 1
• Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous UrticariaTerminatedNCT06077773Phase 2Results posted
• Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous UrticariaCompletedNCT05936567Phase 2Results posted
• A Multicenter, Open-label Phase 3 Study: Ambulatory Blood Pressure Monitoring in Adult Patients With Chronic Spontaneous Urticaria Inadequately Controlled by H1-antihistamines Treated With Remibrutinib up to 12 Weeks.CompletedNCT05795153Phase 3Results posted
• A Study to Assess Subcutaneous Lirentelimab (AK002) in Chronic Spontaneous UrticariaTerminatedNCT05528861Phase 2Results posted
• A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥2 Years to <12 Years of Age With Uncontrolled Chronic Spontaneous Urticaria (CSU) (LIBERTY-CSU CUPIDKids)CompletedNCT05526521Phase 3Results posted
• Rilzabrutinib for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 AntihistamineCompletedNCT05107115Phase 2Results posted
• A Safety and Efficacy Study of Remibrutinib in the Treatment of CSU in Japanese Adults Inadequately Controlled by H1-antihistaminesCompletedNCT05048342Phase 3Results posted
• A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1-antihistaminesCompletedNCT05032157Phase 3Results posted
• A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1 AntihistaminesCompletedNCT05030311Phase 3Results posted
• Study to Compare Efficacy and Safety of TEV-45779 With XOLAIR (Omalizumab) in Adults With Chronic Idiopathic UrticariaCompletedNCT04976192Phase 3Results posted
• Study to Evaluate Tezepelumab in Adults With Chronic Spontaneous UrticariaCompletedNCT04833855Phase 2Results posted
• A Study to Investigate the Use of Benralizumab in Patients With Chronic Spontaneous Urticaria Who Are Symptomatic Despite the Use of Antihistamines (ARROYO)TerminatedNCT04612725Phase 2Results posted
• To Compare Efficacy and Safety of CT-P39 and EU-approved Xolair in Patients With Chronic Spontaneous UrticariaCompletedNCT04426890Phase 3Results posted
• Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With LigelizumabTerminatedNCT04210843Phase 3Results posted
• Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab (LIBERTY-CSU CUPID)CompletedNCT04180488Phase 3Results posted
• A Study of LY3454738 in Adults With Chronic Spontaneous UrticariaTerminatedNCT04159701Phase 2Results posted
• An Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of LOU064 in Subjects With CSUCompletedNCT04109313Phase 2Results posted
• This Was a Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequately Controlled by H1-antihistaminesCompletedNCT03926611Phase 2Results posted
• A Safety and Efficacy Study of Ligelizumab in the Treatment of CSU in Japanese Patients Inadequately Controlled With H1- AntihistaminesCompletedNCT03907878Phase 3Results posted
• A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic DiseasesCompletedNCT03858634Phase 2Results posted
• A Phase III Study of Safety and Efficacy of Ligelizumab in the Treatment of CSU in Adolescents and Adults Inadequately Controlled With H1-antihistaminesCompletedNCT03580369Phase 3Results posted
• A Phase III Study of and Efficacy of Ligelizumab in the Treatment of CSU in Adolescents and Adults Inadequately Controlled With H1-antihistamines.CompletedNCT03580356Phase 3Results posted
• Mepolizumab for the Treatment of Chronic Spontaneous UrticariaCompletedNCT03494881Early Phase 1Results posted
• Study to Investigate the Efficacy and Safety of QGE031 in Adolescent Patients With Chronic Spontaneous Urticaria (CSU)CompletedNCT03437278Phase 2Results posted
• A Study to Assess the Efficacy and Safety of AK002 in Subjects With Antihistamine-Resistant Chronic UrticariaCompletedNCT03436797Phase 2Results posted
• Mast Cell Activation Test in Allergic DiseaseCompletedNCT03406325Results posted
• Study of Efficacy and Safety of Xolair® (Omalizumab) in Chinese Patients With Chronic Spontaneous UrticariaCompletedNCT03328897Phase 3Results posted
• Role of Immunoglobulin E (IgE) Bearing Cells in Chronic Idiopathic Urticaria (CIU)CompletedNCT03111628Phase 4Results posted
• A Safety Extension Study to Evaluate the Long-term Safety of QGE031 in Chronic Spontaneous Urticaria (CSU) PatientsCompletedNCT02649218Phase 2Results posted
• Omalizumab in Chronic Spontaneous Urticaria Patients Non Responding to Initial Standard antihistaminE TreatmentCompletedNCT02550106Phase 4Results posted
• Dose-finding Study of QGE031 as add-on Therapy to Evaluate Efficacy and Safety in Patients With CSUCompletedNCT02477332Phase 2Results posted
• The Validity, Reliability and Interpretability of Thai-version of Chronic Urticaria Quality of Life QuestionnaireCompletedNCT02285023Results posted
• OPTIMA: Efficacy of Optimized Re-treatment and Step-up Therapy With Omalizumab in Chronic Spontaneous Urticaria (CSU) PatientsCompletedNCT02161562Phase 3Results posted
• Efficacy and Safety of Chemoattractant Receptor-homologous Molecule Expressed on T Helper Type 2 (CRTh2) Antagonist AZD1981 in Chronic Idiopathic Urticaria (CIU) AntihistaminesCompletedNCT02031679Phase 2Results posted
• Impact of Omalizumab on Quality of Life Measures and Angioedema Occurrence in Patients With CSU Refractory to TherapyCompletedNCT01723072Phase 3Results posted
• Effect of Omalizumab (Xolair) on Basophils in Patients With Chronic Idiopathic UrticariaCompletedNCT01701583Phase 4Results posted
• Mode of Action Study of Omalizumab in Patients With Chronic Idiopathic Urticaria (CIU) Who Fail to Respond to Antihistamine TreatmentCompletedNCT01599637Phase 2Results posted
• Safety Study of Levocetirizine and FexofenadineCompletedNCT01586091Phase 4Results posted
• A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine Treatment (H1)CompletedNCT01292473Phase 3Results posted
• A Study of the Efficacy and Safety of Omalizumab (Xolair) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine (H1) TreatmentCompletedNCT01287117Phase 3Results posted
• Natural History of Chronic UrticariaCompletedNCT01284426Results posted
• A Safety Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic Despite Treatment With H1 Antihistamines, H2 Blockers, and/or Leukotriene Receptor AntagonistsCompletedNCT01264939Phase 3Results posted
• Efficacy and Safety of Miltefosine in Antihistamine Resistant Chronic UrticariaTerminatedNCT01170949Phase 2Results posted
• A Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic With Antihistamine Treatment (H1)CompletedNCT00866788Phase 2Results posted
• Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 6 Months to 11 MonthsCompletedNCT00628108Phase 3Results posted
• Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown OriginCompletedNCT00619801Phase 3Results posted
• Study for the Treatment of Chronic Idiopathic Urticaria With High Doses of AERIUS (Desloratadine) (Study P04849)CompletedNCT00536380Phase 4Results posted
• Efficacy and Safety of Omalizumab in Adults (18-70 Years) With Moderate to Severe Chronic UrticariaCompletedNCT00481676Phase 2Results posted
• CUTE (Chronic Urticaria Treatment Evaluation)CompletedNCT00264303Phase 4Results posted
• A Trial of HRS-3095 in Healthy VolunteersActive, not recruitingNCT07686484Early Phase 1
• Real-world Evaluation of the Effectiveness of Immunoglobulin-Histamine Complex, IHC (Histoglob) in Chronic UrticariaCompletedNCT07680413
• A Single-Arm Exploratory Study of NatureU Hista Dissolve on Chronic Urticaria SymptomsCompletedNCT07611032Not applicable
• A Real-World Study of Omalizumab Treatment Patterns in Chronic Urticaria Patients in ChinaCompletedNCT07450170
• Efficacy of Bilastine Up-dosing (40 mg ) Versus Combination of Bilastine (20 mg )With Levocitirizine (5 mg) in the Treatment of Chronic Spontaneous UrticariaCompletedNCT07365683Not applicable

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