An observational study in Chronic Urticaria, sponsored by Mahidol University. Completed at 1 site in Thailand. Open to participants aged 4 Years to 15 Years. Per ClinicalTrials.gov, last updated 2016-02-01.
Sponsored by Mahidol University · Observational
The purpose of this study is to examine the natural history of chronic urticaria in children and to identify the predictors for chronic urticaria remission.
A Prospective cohort study of 92 children who were diagnosed with chronic urticaria to investigate the natural course of chronic urticaria and to identify predictors of disease remission.
237 studies on the registry are indexed under Urticaria; 26 are open to participants now.
This study's enrollment of 94 is below the median of 162 across 52 observational studies indexed under Urticaria.
Browse Urticaria studies →Mahidol University is the lead sponsor of 730 studies on the registry; 118 are open to participants now.
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Pediatric allergy clinic, Siriraj Hospital Mahidol University, Thailand, Children 4-15 years of age with chronic urticaria.
Exclusion Criteria:
Chronic urticaria, Natural history
Duration of Urticaria Until Remission Since Chronic Urticaria Was Diagnosed.
Remission rates at 1, 3 and 5 years after the onset of symptoms of chronic urticaria. Description in details: Actually, this study have been started in March 2003 and finally done in March 2009, which would be totally 6 years. We eventually decided to report the rate of CU remissions only at 1, 3 and 5 years after the onset of symptoms because this would be the common interval time of CU symptoms that patients needed to know how long they should have those CU symptoms or how many of them would go away their symptoms within 1, 3 or 5 years. Another reason is that the remission rate of CU between 5 and 6 years was not significantly different, so it might not need to be reported.
Time frame: 6 years
| Milestone | Chronic Urticaria |
|---|---|
| Started | 94 |
| Completed | 92 |
| Not completed | 2 |
Remission rates at 1, 3 and 5 years after the onset of symptoms of chronic urticaria. Description in details: Actually, this study have been started in March 2003 and finally done in March 2009, which would be totally 6 years. We eventually decided to report the rate of CU remissions only at 1, 3 and 5 years after the onset of symptoms because this would be the common interval time of CU symptoms that patients needed to know how long they should have those CU symptoms or how many of them would go away their symptoms within 1, 3 or 5 years. Another reason is that the remission rate of CU between 5 and 6 years was not significantly different, so it might not need to be reported.
| percentage of participants | Chronic Urticaria |
|---|---|
| Remission rate at 1 year after the onset | 18.5 |
| Remission rate at 3 year after the onset | 54 |
| Remission rate at 5 year after the onset | 67.7 |
Collected over 6 years. Actually, this study is the prospective observational study of chronic urticaria for over 6 years regarding only the remission of the disease.. Non-serious events are listed at a 5% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Chronic Urticaria | — | 0/92 (0%) | 62/92 (67.4%) |
| Event | Chronic Urticaria |
|---|---|
| Remission of chronic urticaria (CU) after 5 years of symptomsSkin and subcutaneous tissue disorders | 62/92 |
| Remission of chronic urticaria after 3 years of symptomsSkin and subcutaneous tissue disorders | 50/92 |
| Remission of chronic urticaria after 1 year of symptomsSkin and subcutaneous tissue disorders | 17/92 |
Remission period, chronic urticaria
| Age, Continuous(Years) | Chronic Urticaria |
|---|---|
| Median | 8.4 (4.0 to 15.5) |
| Sex: Female, Male(Participants) | Chronic Urticaria |
|---|---|
| Female | 49 |
| Male | 43 |
| Region of Enrollment(participants) | Chronic Urticaria |
|---|---|
| Thailand | 92 |
This study is completed, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.
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Mahidol University