Cholangitis, Sclerosing: all 149 studies

Page 1 of 2. Open to participants first (38), then studies with results posted, then the rest; newest registration first within each.

• Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic PruritusNot yet recruitingNCT07843420Phase 2
• The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe ItchingNot yet recruitingNCT07678645Phase 2
• Vancomycin Efficacy in Response to Dysbiosis in Atypical ColitisNot yet recruitingNCT07646223Phase 2
• Biodegradable Stents in Primary Sclerosing CholangitisRecruitingNCT07607353Not applicable
• Fecal Microbiota Transplantation for Primary Sclerosing Cholangitis - Randomized Study Versus Sham TransplantationNot yet recruitingNCT07477782Phase 2
• A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing CholangitisRecruitingNCT07387549Phase 3
• Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing CholangitisRecruitingNCT07341282Phase 2
• A Study of TAK-781 in Healthy Volunteers and in Participants With Non-Cirrhotic Primary Sclerosing Cholangitis (PSC)RecruitingNCT07229911Phase 1
• Efficacy and Safety of HK-660S in the Treatment of Primary Sclerosing CholangitisNot yet recruitingNCT06975150Phase 2
• Pharmacologic Approaches to Preventing Primary Sclerosing Cholangitis Recurrence After Liver TransplantationRecruitingNCT06905054Phase 2
• Study with Norucholic Acid Tablets in Patients with Primary Sclerosing Cholangitis (PSC)Not yet recruitingNCT06886360Phase 3
• A Simple Breath Test to Detect Liver Cancer and Monitor Liver ConditionsRecruitingNCT06864195
• Spanish Registry of Autoimmune and Cholestatic Liver Diseases (ColHai)RecruitingNCT06767605
• LEOPARD Prospective Validation Cohort 1RecruitingNCT06723275
• A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSCRecruitingNCT06699121Phase 2
• LEOPARD Training and Validation Data Collection StudyRecruitingNCT06675604
• Spanish Registry of Quality Indicators and Adverse Events of Endoscopic Retrograde CholangiopancreatographyNot yet recruitingNCT06670547
• Liver-gut Axis Study Through Identification of Liver Disease-specific MicrobiomeRecruitingNCT06519162
• A Study of SIPLIZUMAB in AILD and LT PatientsRecruitingNCT06455280Phase 1
• The Effects of Bromelain Supplement in Patients With Ulcerative ColitisRecruitingNCT06351696Not applicable
• FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitisRecruitingNCT06286709Phase 2
• Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSCRecruitingNCT06197308Early Phase 1
• Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics StudyRecruitingNCT05912387Early Phase 1
• Vancomycin in Primary Sclerosing Cholangitis in ItalyRecruitingNCT05876182Phase 2
• Detoxification of the Liver In PSC (Dolphin)RecruitingNCT05835505Phase 2
• A-LiNK: Improving Outcomes in Autoimmune Liver DiseaseRecruitingNCT05750498
• National Database on Primary Sclerosing Cholangitis (PSC)RecruitingNCT05618145
• Clinical Application of Annual Liver Multiscan and MRCP+ in Primary Sclerosing CholangitisNot yet recruitingNCT05462093Not applicable
• Oral Hymecromone to Treat Adolescents and Adults With Primary Sclerosing Cholangitis.RecruitingNCT05295680Phase 2
• Registry for Advanced EndoscopyRecruitingNCT05187312
• Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC PatientsRecruitingNCT04753996
• Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research ApproachRecruitingNCT04685200
• Primary Sclerosing Cholangitis in ChildrenRecruitingNCT04181138
• Biobank for Cholestatic Liver Diseases.RecruitingNCT03445585
• MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver DiseaseRecruitingNCT03178630
• MRI Based Biomarkers in Pediatric Autoimmune Liver DiseaseRecruitingNCT03175471
• Swiss Primary Sclerosing Cholangitis Cohort StudyRecruitingNCT03146936
• Treating Primary Sclerosing Cholangitis and Biliary Atresia With VancomycinRecruitingNCT02137668Phase 1
• Safety and Tolerability of A3907 in Primary Sclerosing CholangitisTerminatedNCT05642468Phase 2Results posted
• Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing CholangitisCompletedNCT05525520Phase 2Results posted
• CM-101 in PSC Patients -The SPRING StudyCompletedNCT04595825Phase 2Results posted
• Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC)CompletedNCT04480840Phase 2Results posted
• Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated CirrhosisTerminatedNCT04060147Phase 1Results posted
• A Study to Evaluate the Safety, and Tolerability, and Efficacy of Seladelpar in Patients With PSCTerminatedNCT04024813Phase 2Results posted
• Study of Cilofexor in Adults With Primary Sclerosing CholangitisTerminatedNCT03890120Phase 3Results posted
• Vidofludimus Calcium for Primary Sclerosing CholangitisCompletedNCT03722576Phase 2Results posted
• Vancomycin for Primary Sclerosing CholangitisTerminatedNCT03710122Phase 2/3Results posted
• A Research Study to Evaluate Safety and Efficacy of DUR-928 in Subjects With Primary Sclerosing Cholangitis (PSC)TerminatedNCT03394781Phase 2Results posted
• An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing CholangitisTerminatedNCT03359174Phase 2Results posted
• A POC and Dose-Ranging Study of HTD1801 in PSC PatientsCompletedNCT03333928Phase 2Results posted
• A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC)CompletedNCT02978339Phase 1/2Results posted
• Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without CirrhosisCompletedNCT02943460Phase 2Results posted
• Pharmacokinetics and Pharmacodynamics of Cilofexor in Adults With Normal and Impaired Hepatic FunctionCompletedNCT02808312Phase 1Results posted
• A Study of NGM282 in Patients With Primary Sclerosing CholangitisCompletedNCT02704364Phase 2Results posted
• PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Participants With Primary Sclerosing CholangitisCompletedNCT02653625Phase 2Results posted
• Fecal Microbiota Transplantation for the Treatment of Primary Sclerosing Cholangitis.CompletedNCT02424175Phase 1/2Results posted
• Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)CompletedNCT02177136Phase 2Results posted
• Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing CholangitisCompletedNCT02061540Phase 2Results posted
• Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CTCompletedNCT01879735Phase 1Results posted
• Primary Sclerosing Cholangitis With Oral Vancomycin by the Study of Its Antimicrobial and Immunomodulating EffectsCompletedNCT01802073Phase 3Results posted
• Simtuzumab (GS-6624) in the Prevention of Progression of Liver Fibrosis in Adults With Primary Sclerosing Cholangitis (PSC)CompletedNCT01672853Phase 2Results posted
• Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With VancomycinCompletedNCT01322386Phase 1Results posted
• Pilot Study of Fenofibrate for PSCTerminatedNCT01142323Phase 1/2Results posted
• A Pilot Study of Vancomycin or Metronidazole in Patients With Primary Sclerosing CholangitisCompletedNCT01085760Phase 1Results posted
• Thalidomide for the Treatment of Primary Sclerosing Cholangitis (PSC)TerminatedNCT00953615Phase 2Results posted
• Trial of High-dose Urso in Primary Sclerosing CholangitisTerminatedNCT00059202Phase 2/3Results posted
• Deciphering the Self-antigen Specific T Cell Signature of Autoimmune Liver DiseasesCompletedNCT07784881
• Endoscopy and Primary Sclerosing CholangitisCompletedNCT06686810
• A Multi-center Evaluation of Aldafermin in a Randomized, Double-blind, Placebo-controlled Study in Subjects With Primary Sclerosing Cholangitis.WithdrawnNCT06654726Phase 2/3
• Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)Active, not recruitingNCT06553768Phase 3
• A Study Evaluating the Safety, Tolerability, and Efficacy of Aramchol Meglumine in Primary Sclerosing CholangitisWithdrawnNCT06095986Phase 2
• TruGraf Liver Gene Expression Serial TestTerminatedNCT06061341
• Subcutaneous Doses of CM-101 as a Treatment for Medical Conditions Involving Inflammatory and Fibrotic Mechanisms in Healthy Male SubjectsCompletedNCT06037577Phase 1
• S-adenosylmethionine (SAMe) in Patients With Primary Sclerosing Cholangitis (PSC)CompletedNCT06026865Not applicable
• Gluten-free Diet in PSC and IBDCompletedNCT06026449Not applicable
• CS0159 in Chinese Patients With PSC (Primary Sclerosing Cholangitis)Active, not recruitingNCT05896137Phase 2
• Evaluation of the Safety and Efficacy of HK-660S in Patients With Primary Sclerosing CholangitisCompletedNCT05866809Phase 2
• A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis.Active, not recruitingNCT05627362Phase 2
• Multicenter Observational Study of PSC and IgG4-SC in ChinaStatus unknownNCT05463445
• Biliary Interventions in Critically Ill Patients With Secondary Sclerosing Cholangitis (BISCIT)TerminatedNCT05396755Not applicable
• A Systems Biology Approach for Identification of Host and Microbial Mechanisms and Druggable Targets for the Treatment of PSC-IBDStatus unknownNCT05376228
• Value of MRCP+ And Liver Multiscan in the Management of Dominant Strictures in Primary Sclerosing CholangitisStatus unknownNCT05359497Not applicable
• SSC-COVID in Patients After COVID-19CompletedNCT05233553
• Predictive Models of Hepatic Decompensation and Survival Outcomes in Pediatric Patients With CirrhosisStatus unknownNCT05181332
• Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CS0159CompletedNCT05082779Phase 1
• PSC Clinical Epidemiology in ChinaActive, not recruitingNCT04981756
• A Pilot Study Examining Diet in Primary Sclerosing CholangitisCompletedNCT04678219Not applicable
• A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)Active, not recruitingNCT04663308Phase 2
• Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid TherapyStatus unknownNCT04309773Phase 3
• Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC)Active, not recruitingNCT04133792Phase 3
• Quantitative Magnetic Resonance Imaging in Biliary Disease: Health Economics StudyWithdrawnNCT04015310
• Gluten-free Diet in Patients With Primary Sclerosing Cholangitis (PSC)CompletedNCT04006886Not applicable
• Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management StudyStatus unknownNCT03951324
• norUrsodeoxycholic Acid vs Placebo in PSCActive, not recruitingNCT03872921Phase 3
• Repeatability and Reproducibility of Quantitative MRCPCompletedNCT03809559
• Cholangioscopy in Primary Sclerosing Cholangitis (PSC)CompletedNCT03766035
• Repeatability and Reproducibility of Multiparametric MRICompletedNCT03743272
• A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)WithdrawnNCT03678480Phase 2
• Sulfasalazine for the Treatment of Primary Sclerosing CholangitisCompletedNCT03561584Phase 2
• Umbilical Cord Mesenchymal Stem Cells in Primary Sclerosing CholangitisStatus unknownNCT03516006Phase 1/2

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