CADASIL clinical trials

The registry lists 33 studies for CADASIL across more than 10 countries. 18 are recruiting or about to start. 24 of them are mainly about CADASIL (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-23.

Get an email when these change. Save the CADASIL studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

Watch these studies

See an example email

Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Recruiting: 14
Completed: 9
Not yet recruiting: 3
Status unknown: 3
Active, not recruiting: 2
Withdrawn: 1

Phase

Phase 2: 7
Phase 1: 1

Where

United States: 9
Italy: 5
France: 5
China: 3
United Arab Emirates: 2
Germany: 1

Who runs them

Assistance Publique - Hôpitaux de Paris (4) · Mayo Clinic (3) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (3) · University of Wisconsin, Madison (2) · Institut National de la Santé Et de la Recherche Médicale, France (2) · MD Stem Cells (2) · Children's Hospital of Philadelphia (2) · Perminder Sachdev (1)

What is being tested here

Drugs under test in CADASIL studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	All
Cilostazol	1	1
Cerebrolysin	0	1
Tocotrienols	0	1
Adrenomedullin	0	1
Dabigatran	0	1
Fremanezumab	0	1

Coming up

0phase 3 studies under way

6studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6

Dec 2026Taiwan Associated Genetic and Nongenetic Small Vessel Disease · National Taiwan University Hospital
Mar 2027AusCADASIL: An Australian Cohort of CADASIL · Perminder Sachdev
Apr 2027Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASIL · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Jun 2027Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study · University of Wisconsin, Madison
Jul 2027Neurologic Stem Cell Treatment Study · MD Stem Cells
Oct 2027Registry for CADASIL · University of Wisconsin, Madison

Who these studies take

Of the 14 CADASIL studies recruiting now, 11 (79%) set no upper age limit and 1 (7%) stop at 75 or younger. 2 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 8 (57%) take healthy volunteers.

Recruiting studies that take each age, of 14
Age	Women	Men
10	1 (7%)	1 (7%)
18	12 (86%)	12 (86%)
30	14 (100%)	14 (100%)
40	14 (100%)	14 (100%)
50	14 (100%)	14 (100%)
65	14 (100%)	14 (100%)
75	13 (93%)	13 (93%)
85	13 (93%)	13 (93%)

Across all 33 studies, recruiting or not: 18% stop at 75 or younger and 9% at 65; 12% take children; 0% are for women only and 0% for men only; 42% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 33 of 33. search them.