CADASIL clinical trials
The registry lists 36 studies for CADASIL across more than 10 countries. 19 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-03.
Status
- Recruiting
- 15
- Completed
- 10
- Active, not recruiting
- 3
- Not yet recruiting
- 3
- Status unknown
- 3
- Enrolling by invitation
- 1
Phase
- Phase 2
- 8
- Phase 1
- 1
Where
- United States
- 10
- France
- 5
- Italy
- 5
- China
- 3
- Spain
- 2
- United Arab Emirates
- 2
Who runs them
Assistance Publique - Hôpitaux de Paris (4) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (3) · Mayo Clinic (3) · Children's Hospital of Philadelphia (2) · University of Wisconsin, Madison (2) · MD Stem Cells (2) · Institut National de la Santé Et de la Recherche Médicale, France (2) · Fondation Hôpital Saint-Joseph (1)
Studies
Recruiting first, then most recently updated. Showing 36 of 36 — search for more.
- Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy.RecruitingNCT069332121 country
- Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASILRecruitingNCT069381002 countries
- Retina is a Marker for Cerebrovascular HeathRecruitingNCT04753970Phase 1/21 country
- Safety and Efficacy of Edaravone Dexborneol Sublingual Tablets for Blood-Brain Barrier Dysfunction in CADASILNot yet recruitingNCT07692399Phase 21 country
- Neurologic Stem Cell Treatment StudyRecruitingNCT02795052Not applicable2 countries
- Biological Collection of the Rare Diseases of the Brain and Eye Vessels Cohort - 2Not yet recruitingNCT07650110Not applicable
- Long-term Prospective Study of Korean CADASIL PatientsRecruitingNCT074978671 country
- Neurogenetic And Hemodynamic Of Migraine Aura And PfoRecruitingNCT073490041 country
- Taiwan Associated Genetic and Nongenetic Small Vessel DiseaseRecruitingNCT054736371 country
- Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) StudyRecruitingNCT056778801 country
- The Myelin Disorders Biorepository ProjectRecruitingNCT030473691 country
- Registry for CADASILRecruitingNCT055677441 country
- Development and Validation of a Functional MRI Biomarker of Cerebral Small Vessel Dysfunction in CADASILNot yet recruitingNCT06859658
- AusCADASIL: An Australian Cohort of CADASILRecruitingNCT061480511 country
- Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment StudyEnrolling by invitationNCT03724136Not applicable2 countries
- CADASIL Registry StudyRecruitingNCT043100981 country
- MRI Study of Blood-brain Barrier Function in CADASILRecruitingNCT059020391 country
- Comparative Study Between Alzheimer's and Multi-infarct DementiaRecruitingNCT057811391 country
- Prognosis of Cerebral Small Vessel DiseaseRecruitingNCT057343781 country
- Florida Cerebrovascular Disease Biorepository and Genomics CenterActive, not recruitingNCT054919801 country
- RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)CompletedNCT069355781 country
- Imaging Study of Neurovascular Coupling in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)CompletedNCT020717841 country
- Efficacy and Safety of Tocotrienols in CADASILCompletedNCT04658823Phase 21 country
- LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for LeukodystrophiesCompletedNCT026991901 country
- Generation of a Cellular Model of CADASIL From Skin FibroblastsCompletedNCT020322251 country
- CERebrolysin in CADASILActive, not recruitingNCT05755997Phase 21 country
- Adrenomedullin for CADASILCompletedNCT06072118Phase 21 country
- Establishment of a CSF Bank for the Development of Biomarkers of Smooth Muscle Cell (SMC) Damage in Monogenic Cerebral Small Vessel DiseaseStatus unknownNCT05793424
- Virtual Individual Cognitive Stimulation Therapy: a Proof of Concept StudyActive, not recruitingNCT04828434Not applicable1 country
- Safety and Efficacy of Fremanezumab for Migraine in Adult CADASILWithdrawnNCT04334408Phase 2
- Development of New Biomarkers With Magnetic Resonance Imaging for Longitudinal Studies in CADASIL AngiopathyStatus unknownNCT040360841 country
- The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage?CompletedNCT028373541 country
- Impact of tDCS on Cerebral AutoregulationCompletedNCT01865604Not applicable1 country
- The Efficacy, Safety, And Tolerability Of Donepezil HCl (E2020) In Patients With CADASIL Who Have Cognitive ImpairmentCompletedNCT00103948Phase 23 countries
- Safety Study of Dabigatran in CADASILStatus unknownNCT01361763Phase 21 country
- Research Study on Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)CompletedNCT011148151 country