Bronchiolitis Obliterans clinical trials
The registry lists 82 studies for Bronchiolitis Obliterans across more than 10 countries. 9 are recruiting or about to start. 56 of them are mainly about Bronchiolitis Obliterans (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27. Counting its narrower condition Bronchiolitis Obliterans Syndrome too: 778 studies, 134 open.
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Who runs them
Hannover Medical School (4) · Assistance Publique - Hôpitaux de Paris (4) · Johann Wolfgang Goethe University Hospital (4) · Children's Hospital Medical Center, Cincinnati (3) · APT Pharmaceuticals, Inc. (3) · FLUIDDA nv (3) · Zambon SpA (3) · M.D. Anderson Cancer Center (2)
What is being tested here
Drugs under test in Bronchiolitis Obliterans studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Albuterol | 1 | 0 | 3 |
| Belumosudil | 1 | 0 | 1 |
| Vimseltinib | 1 | 0 | 1 |
| Cyclosporine | 0 | 5 | 6 |
| Azithromycin | 0 | 0 | 5 |
| Montelukast | 0 | 0 | 4 |
| Pirfenidone | 0 | 1 | 2 |
| Etanercept | 0 | 0 | 2 |
| Formoterol | 0 | 0 | 2 |
| Budesonide | 0 | 0 | 2 |
Drug classes tested here Bronchodilators 1 open · Tyrosine kinase inhibitors (TKIs) 1 open · Calcineurin inhibitors 6 · Corticosteroids 5 · JAK inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Bronchial Epithelium of Children With Post-infectious Bronchiolitis Obliterans · Institut National de la Santé Et de la Recherche Médicale, France
- Jun 2027BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP) · Dana-Farber Cancer Institute
- Nov 2027Treatment of Pediatric Bronchiolitis Obliterans by Airway Basal Stem Cells · Regend Therapeutics
Who these studies take
Of the 9 Bronchiolitis Obliterans studies recruiting now, 5 (56%) set no upper age limit and 4 (44%) stop at 75 or younger. 7 (78%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (22%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (67%) | 6 (67%) |
| 18 | 8 (89%) | 8 (89%) |
| 30 | 6 (67%) | 6 (67%) |
| 40 | 5 (56%) | 5 (56%) |
| 50 | 5 (56%) | 5 (56%) |
| 65 | 5 (56%) | 5 (56%) |
| 75 | 5 (56%) | 5 (56%) |
| 85 | 5 (56%) | 5 (56%) |
Across all 82 studies, recruiting or not: 38% stop at 75 or younger and 26% at 65; 43% take children; 0% are for women only and 2% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 82. Browse all 82 → or search them.
- Evaluating Clonogenic Epithelial Cell Populations in Patients With Bronchiolitis Obliterans SyndromeRecruitingNCT046045221 country
- Bronchial Epithelium of Children With Post-infectious Bronchiolitis ObliteransRecruitingNCT06140901Not applicable1 country
- Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLADRecruitingNCT074348691 country
- TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT PatientsRecruitingNCT040984451 country
- BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)RecruitingNCT05922761Phase 21 country
- Treatment of Pediatric Bronchiolitis Obliterans by Airway Basal Stem CellsRecruitingNCT07239895Early Phase 11 country
- A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)RecruitingNCT06619561Phase 21 country
- Measures of Respiratory Health (MRH)RecruitingNCT026578371 country
- Evaluating Bronchodilator Response in Patients With BronchiectasisRecruitingNCT05932316Not applicable1 country
- Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell TransplantationCompletedNCT03805477Phase 22 countries
- Hp129 Xenon Imaging and BOS in Lung TransplantationCompletedNCT03603899Phase 1/21 country
- A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of ItacitinibTerminatedNCT04640025Phase 29 countries
- Study of Pulmonary MRI for the Diagnosis of Bronchiolitis Obliterans Syndrome After Allogeneic Stem Cell TransplantationCompletedNCT04080232Not applicable1 country
- Extension Trial on Efficacy / Safety of L-CsA + SoC in Treating BOS in Post Single or Double Lung Transplant (BOSTON-3)TerminatedNCT04039347Phase 39 countries
- Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell TransplantTerminatedNCT04908735Phase 21 country
- Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2)CompletedNCT03656926Phase 39 countries
- Prospective Evaluations of Infectious Complication in Lung Transplant RecipientsCompletedNCT001779181 country
- TRAnscriptional Profile of Peripheral Blood Cells in Patient With Chronic Kidney and Lung Rejection: Correlation With Response to Extracorporeal Photo-aphereSiSActive, not recruitingNCT073168291 country
- Itacitinib for the Treatment of Bronchiolitis Obliterans Syndrome After Donor Hematopoietic Cell TransplantTerminatedNCT04239989Phase 11 country
- Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1)CompletedNCT03657342Phase 37 countries
- Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre TransplantationTerminatedNCT04655508Phase 31 country
- High Intensity Intervallic Training in Children With Bronchiolitis ObliteransCompletedNCT05881538Not applicable1 country
- Microparticles and Bronchiolitis Obliterans SyndromeCompletedNCT024582741 country
- Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant RecipientsCompletedNCT01650545Phase 1/21 country
- 4DX for the Diagnosis of Constrictive BronchiolitisCompletedNCT04489758Not applicable1 country
- The Safety and Tolerability of Pirfenidone for BOS After HCTCompletedNCT03315741Phase 11 country
- A Study to Evaluate the Potential of Mesenchymal Stromal Cells to Treat Obliterative Bronchiolitis After Lung TransplantationCompletedNCT01175655Phase 11 country
- INSPIRE Continuation Post-Approval StudyCompletedNCT038689049 countries
- Efficacy and Safety of Azithromycin in Patients With Bronchiolitis ObliteransCompletedNCT05299567Phase 4
- Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post AllotransplantTerminatedNCT01432080Phase 21 country
- Mesenchymal Stem Cell Therapy for Lung RejectionCompletedNCT02181712Phase 11 country
- COVID-19 Pathophysiology of Long Term ImplicationsStatus unknownNCT04813575Not applicable1 country
- Macitentan in the Treatment of Organ Rejection After Lung TransplantationWithdrawnNCT02893176Phase 41 country
- Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans SyndromeCompletedNCT01287078Phase 21 country
- Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis ObliteransCompletedNCT01273207Phase 21 country
- Viral Triggers in Pediatric Lung TransplantationCompletedNCT008918651 country
- Sleep Disorders in Bronchiolitis Obliterans Syndrome 2&3WithdrawnNCT02109237Not applicable1 country
- Prospective Study of Belated Pulmonary Complications Occurring in Children Treated With Allogeneic Hematopoietic Stem Cells.CompletedNCT02032381Not applicable1 country
- A Proposal to Test the Efficacy and Tolerability of Bortezomib in Pulmonary Chronic GVHDTerminatedNCT01163786Phase 21 country
- Iraq- Afghanistan War Lung Injury Using 19F MRI (DIAL1001006)CompletedNCT03237364Early Phase 11 country
- European Trial of Pirfenidone in BOS, A European Multi-center StudyCompletedNCT02262299Phase 2/37 countries
- Hyperpolarized 129Xe MRI for the Assessment of BOS With Late Onset LONIPCStatus unknownNCT040296361 country
- Forced Oscillations for Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow TransplantationCompletedNCT02902471Not applicable1 country
- Immune Mechanisms of Rejection in Human Lung AllograftsCompletedNCT00861900
- Montelukast to Treat Bronchiolitis ObliteransCompletedNCT00656058Phase 21 country
- Prospective Study for Transplant Optimization Using Functional Imaging (TROFI)TerminatedNCT02488304Phase 21 country
- Targeted Therapy of Bronchiolitis Obliterans SyndromeCompletedNCT01307462Phase 21 country
- MSC for Treatment of Interstitial Lung Disease After Allo-HSCTStatus unknownNCT02543073Phase 1/21 country
- Transplant Optimization Using Functional Imaging (TROFI)CompletedNCT02441413Not applicable1 country
- Transplant Optimization Using Functional ImagingCompletedNCT02364674Not applicable1 country