Brain Neoplasms: all 1,993 studies

Page 7 of 20. Open to participants first (516), then studies with results posted, then the rest; newest registration first within each.

• Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer (NSCLC)CompletedNCT02681549Phase 2Results posted
• MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived TumorsTerminatedNCT02669914Phase 2Results posted
• An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)CompletedNCT02667587Phase 3Results posted
• Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With GlioblastomaCompletedNCT02661282Phase 1/2Results posted
• Stereotactic Radiosurgery (SRS) Dose-Escalation Study for Brain MetastasisActive, not recruitingNCT02645487Not applicableResults posted
• Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)TerminatedNCT02624388Phase 2Results posted
• An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)CompletedNCT02617589Phase 3Results posted
• Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal MetastasesCompletedNCT02616393Phase 2Results posted
• Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain MetastasesCompletedNCT02595905Phase 2Results posted
• Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine TumorsActive, not recruitingNCT02589522Phase 1Results posted
• Treatment of Brain Metastases From Breast Cancer With Eribulin MesylateCompletedNCT02581839Phase 2Results posted
• Pre-operative Stereotactic Radiosurgery Followed by Resection for Brain MetastasesCompletedNCT02514915Not applicableResults posted
• Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain MetastasesTerminatedNCT02490878Phase 2Results posted
• Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)TerminatedNCT02460874Phase 1/2Results posted
• Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate SystemCompletedNCT02392078Results posted
• Perampanel in Seizure Patients With Primary Glial Brain TumorsCompletedNCT02363933Phase 4Results posted
• Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain MetastasesCompletedNCT02360215Phase 3Results posted
• Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused UltrasoundCompletedNCT02343991Not applicableResults posted
• A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)TerminatedNCT02343549Phase 2Results posted
• Bioequivalence Study of Temozolomide in Patients With Primary Tumors of the Central Nervous SystemCompletedNCT02343081Phase 4Results posted
• 1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor PatientsCompletedNCT02334722Phase 4Results posted
• Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade GliomasCompletedNCT02323880Phase 1Results posted
• Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast CancerCompletedNCT02312622Phase 2Results posted
• A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the BrainCompletedNCT02308020Phase 2Results posted
• Study of MEK162 for Children With Low-Grade GliomasCompletedNCT02285439Phase 1/2Results posted
• Study of Lacosamide as an Adjunctive Drug Treatment for Epilepsy in Patients With Brain TumorsCompletedNCT02276053Results posted
• Cabozantinib +/- Trastuzumab In Breast Cancer Patients w/ Brain MetastasesCompletedNCT02260531Phase 2Results posted
• Phase II Study of Cobimetinib in Combination With Vemurafenib in Active Melanoma Brain MetastasesTerminatedNCT02230306Phase 2Results posted
• IDH1 Peptide Vaccine for Recurrent Grade II GliomaCompletedNCT02193347Phase 1Results posted
• 18F-FLT PET/CT in Measuring Cell Proliferation in Patients With Brain TumorsCompletedNCT02167204Not applicableResults posted
• Trial of Cabozantinib (XL184) in Non-Small Cell Lung Cancer With Brain MetastasesTerminatedNCT02132598Phase 2Results posted
• GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain MetastasesCompletedNCT02115139Phase 2Results posted
• Ipilimumab Induction in Patients With Melanoma Brain Metastases Receiving Stereotactic RadiosurgeryTerminatedNCT02097732Phase 2Results posted
• MK-3475 in Melanoma and NSCLC Patients With Brain MetastasesCompletedNCT02085070Phase 2Results posted
• Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant GliomaActive, not recruitingNCT02062827Phase 1Results posted
• Fractionated Stereotactic Radiosurgery for Large Brain MetastasesCompletedNCT02054689Not applicableResults posted
• Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain TumorsCompletedNCT02052648Phase 1/2Results posted
• A Phase II Study of Dacomitinib in Progressive Brain MetastasesTerminatedNCT02047747Phase 2Results posted
• Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the BrainCompletedNCT02039947Phase 2Results posted
• Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain TumorsCompletedNCT02038218Phase 2Results posted
• Efficacy Evaluation of Dotarem®-Enhanced MRI Compared to Gadovist®/Gadavist®-Enhanced MRI in the Diagnosis of Brain TumorsCompletedNCT02034708Phase 4Results posted
• MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After RadiotherapyCompletedNCT02031237Results posted
• Yellow 560 Microscope for Intraoperative Visualization of Fluorescein Stained Intracranial LesionsTerminatedNCT02028325Phase 4Results posted
• A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain TumorsTerminatedNCT02006407Not applicableResults posted
• STAR Cape+BKM120 MBC With Brain MetCompletedNCT02000882Phase 2Results posted
• F18 EF5 PET/CT Imaging in Patients With Brain Metastases From Breast CancerCompletedNCT01985971Not applicableResults posted
• Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and MetabolitesTerminatedNCT01978236Phase 2Results posted
• Photodynamic Therapy (PDT) For Recurrent High Grade GliomasTerminatedNCT01966809Phase 2Results posted
• Nicardipine vs Esmolol Craniotomy EmergenceCompletedNCT01951950Phase 1Results posted
• Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior BevacizumabCompletedNCT01931098Phase 2Results posted
• Optune(NOVOTTF-100A)+ Bevacizumab+ Hypofractionated Stereotactic Irradiation Bevacizumab-Naive Recurrent Glioblastoma (GCC 1344)TerminatedNCT01925573Not applicableResults posted
• NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent GlioblastomaCompletedNCT01894061Phase 2Results posted
• Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT)CompletedNCT01854554Phase 2Results posted
• A Proof-of-principle Study of HBO-SRS for Brain MetastasesCompletedNCT01850563Not applicableResults posted
• Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade GliomaCompletedNCT01817751Phase 2Results posted
• Phase 2 Study of Neoadjuvant Vemurafenib in Melanoma Patients With Untreated Brain MetastasesCompletedNCT01781026Phase 2Results posted
• Intraoperative MRI-guidance in Frameless Stereotactic BiopsiesTerminatedNCT01779219Not applicableResults posted
• Intra-operative Use of Indigo Carmine Dye for the Delineation of Ill Defined Tumor Borders Using Stereotactic InjectionCompletedNCT01767415Phase 1/2Results posted
• Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma PatientsCompletedNCT01738646Phase 2Results posted
• Hypofractionated Stereotactic Radiosurgery in Treating Patients With Large Brain MetastasisCompletedNCT01705548Not applicableResults posted
• A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent SubjectsCompletedNCT01677741Phase 1/2Results posted
• Comparison of Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Adults With Brain Metastases From Non-Small Cell Lung CancerCompletedNCT01657799Phase 2Results posted
• Laser Ablation After Stereotactic RadiosurgeryCompletedNCT01651078Results posted
• Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma MultiformeCompletedNCT01648348Phase 1/2Results posted
• Cerebral Blood Perfusion Changes After General Anesthesia for CraniotomyCompletedNCT01642147Not applicableResults posted
• Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast CancerCompletedNCT01622868Phase 2Results posted
• Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain TumorsCompletedNCT01609790Phase 2Results posted
• A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor ProgressionCompletedNCT01604512Not applicableResults posted
• Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent GlioblastomaTerminatedNCT01582152Phase 1/2Results posted
• Pilot Study Effect of Sulfasalazine on Glutamate Levels by(Magnetic Resonance Spectroscopy)MRS in Patients With GliomaCompletedNCT01577966Not applicableResults posted
• PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404CompletedNCT01540513Not applicableResults posted
• Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.CompletedNCT01520870Phase 2Results posted
• Evaluation of the Use of Trental and Vitamin E For Prophylaxis of Radiation NecrosisCompletedNCT01508221Phase 2Results posted
• Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation TherapyCompletedNCT01503086Not applicableResults posted
• GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L)TerminatedNCT01497665Phase 2Results posted
• CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIIICompletedNCT01454596Phase 1/2Results posted
• Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain MetastasesCompletedNCT01441596Phase 2Results posted
• Phase I-II Everolimus and Sorafenib in Recurrent High-Grade GliomasCompletedNCT01434602Phase 1/2Results posted
• Hippocampal-Avoiding Whole Brain Irradiation With Simultaneous Integrated Boost for Treatment of Brain MetastasesCompletedNCT01414738Phase 2Results posted
• Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain TumorCompletedNCT01381718Phase 2Results posted
• Phase II Study of BKM120 for Subjects With Recurrent GlioblastomaCompletedNCT01339052Phase 2Results posted
• A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain MetastasesCompletedNCT01305941Phase 2Results posted
• Carboplatin and Bevacizumab for Recurrent EpendymomaCompletedNCT01295944Phase 2Results posted
• Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain IrradiationCompletedNCT01288235Phase 2Results posted
• A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the BrainCompletedNCT01266967Phase 2Results posted
• A Study of RO5185426 in Previously Treated Melanoma Patients With Brain MetastasesCompletedNCT01253564Phase 2Results posted
• FLT-PET Imaging of Brain Tumors in ChildrenCompletedNCT01244737Phase 2Results posted
• Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain MetastasesCompletedNCT01227954Phase 2Results posted
• RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast CancerTerminatedNCT01217411Phase 1/2Results posted
• A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade GliomasCompletedNCT01188096Phase 2Results posted
• A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain TumorsCompletedNCT01128218Phase 1/2Results posted
• Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma MultiformCompletedNCT01120639Phase 1/2Results posted
• Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the BrainTerminatedNCT01116661Phase 2Results posted
• TPI 287 in Patients With Recurrent Glioblastoma MultiformeTerminatedNCT01113463Phase 2Results posted
• Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)TerminatedNCT01110876Phase 1/2Results posted
• Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade GliomaTerminatedNCT01105702Phase 2Results posted
• Effects of Methylphenidate on Attention Deficits in Childhood Cancer SurvivorsTerminatedNCT01100658Not applicableResults posted
• Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade GliomaTerminatedNCT01095094Phase 2Results posted
• Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second RelapseTerminatedNCT01068782Phase 2Results posted
• Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)CompletedNCT01067469Phase 2Results posted

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