Brain Neoplasms: all 1,993 studies

Page 11 of 20. Open to participants first (516), then studies with results posted, then the rest; newest registration first within each.

• CBT for Insomnia in Primary Brain Tumor PatientsCompletedNCT04919993Not applicable
• Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases in NSCLCCompletedNCT04912128
• Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLCStatus unknownNCT04905550Phase 2
• Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid TumorsTerminatedNCT04901806Phase 1
• A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRTTerminatedNCT04897880Phase 2
• Radiosurgery Before Surgery for the Treatment of Brain MetastasesCompletedNCT04895592Early Phase 1
• Detection and Metabolic Characterization in DOPA PET/CT of Brain MetastasesCompletedNCT04890028Not applicable
• Durvalumab (MEDI4736) and Radiosurgery (fSRT Vs. PULSAR) for the Treatment of Non-Small Cell Lung Cancer Brain MetastasesWithdrawnNCT04889066Phase 2
• Almonertinib Versus Osimertinib in the Patients With EGFR Mutations in Advanced NSCLC With Brain MetastasesStatus unknownNCT04870190Phase 3
• Neuro-pharmacological Properties of Repurposed Ketoconazole in GlioblastomasTerminatedNCT04869449Early Phase 1
• Finding New Targets by Proteomic Approaches (InnovRT1)CompletedNCT04868799
• Pediatric Prospective Personalized Immune and Target Identification TrialCompletedNCT04859543Not applicable
• Evaluation of Neratinib for Treatment and Prevention of Subsequent CNS Event(s) in Patients With Brain Metastasis of Advanced HER2 Positive Breast CancerWithdrawnNCT04856475Phase 2
• Radiotherapy Combined With Immunotherapy for Brain Metastases of Non-small Cell Lung CancerSuspendedNCT04835025
• Sequence of Radiation and Targeted Therapy in Brain MetastasesCompletedNCT04832672
• A Tailored Exercise Oncology Program for Neuro-Oncology PatientsStatus unknownNCT04831190Not applicable
• Keynatinib in Treated Patients with NSCLC and Brain MetastasesCompletedNCT04824079Phase 2
• Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or GliosarcomaCompletedNCT04817254Phase 2
• Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain MetastasesActive, not recruitingNCT04808752Phase 2
• Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking AbilityActive, not recruitingNCT04804644Phase 3
• Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain MetastasesStatus unknownNCT04801342Phase 2
• Stereotactic Radiotherapy in Association With Immunotherapy for the Treatment of NSCLC Brain MetastasesStatus unknownNCT04787185
• Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic RadiosurgeryActive, not recruitingNCT04785521
• A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)Status unknownNCT04778800Not applicable
• Multimodality MRI and Liquid Biopsy in GBMWithdrawnNCT04776980Early Phase 1
• MEP and Neuromuscular BlockerCompletedNCT04768400Not applicable
• A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast CancerStatus unknownNCT04767828Phase 4
• A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma MultiformeActive, not recruitingNCT04762069Phase 2
• 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain MetastasesCompletedNCT04752267Early Phase 1
• Phase II Study of T-DX in HER2-positive Breast Cancer Brain MetastasesCompletedNCT04752059Phase 2
• Genomic Study in Non-small Cell Lung Cancer Brain MetastasisCompletedNCT04745715
• Handheld Dynamometer During Awake Craniotomy PilotCompletedNCT04742231Not applicable
• Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Brain TumorsCompletedNCT04738162Phase 2
• Glioma Supra Marginal Incision TrialCompletedNCT04737577Not applicable
• SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain TissueCompletedNCT04734444Not applicable
• Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.TerminatedNCT04712721Early Phase 1
• Use of Non-invasive Optical Analysis in NeurosurgeryStatus unknownNCT04712214Not applicable
• Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain MetastasesActive, not recruitingNCT04711824Phase 1/2
• Feasibility of MRI Workflow Alone in External Radiotherapy for the Treatment of Brain and Prostate TumorsCompletedNCT04704804
• Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) MetastasesCompletedNCT04700748Not applicable
• Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II StudyActive, not recruitingNCT04690348Phase 2
• Revision of the EORTC QLQ-BN20 QuestionnaireStatus unknownNCT04689321
• Central Nervous System(CNS) Efficacy of DacomitinibStatus unknownNCT04675008Phase 2
• Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced MelanomaActive, not recruitingNCT04674683Phase 3
• HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their CaregiversCompletedNCT04670016
• Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma PatientsCompletedNCT04657315Phase 1/2
• SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung CancerWithdrawnNCT04650490Phase 2
• Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain MetastasesActive, not recruitingNCT04647916Phase 2
• A Phase II Trial of Upfront Radiotherapy Plus Almonertinib for Epidermal Growth Factor Receptor(EGFR)-Mutant Non-small-cell Lung Cancer(NSCLC) Patients With Brain MetastasesStatus unknownNCT04643847Phase 2
• Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain MetastasisStatus unknownNCT04639271Phase 2
• Role and Value of Inflammatory Markers in Brain Tumors : A Case Controlled StudyCompletedNCT04634188
• Multi -paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain MetastasesStatus unknownNCT04626206
• Stereotactic Radiosurgery With Abemaciclib, Ribociclib, or Palbociclib in Treating Patients With Hormone Receptor Positive Breast Cancer With Brain MetastasesWithdrawnNCT04585724Phase 1
• Changes in the MRI Signal in Patients With Benign Tumors of the Brain and Meninges Treated With Proton Therapy: Impact of TEL and the Biological Dose ReceivedCompletedNCT04584086Not applicable
• Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain MetastasesStatus unknownNCT04582968Phase 1/2
• Survivorship Study of Cancer Patients Who Received Cranial Radiation TherapyTerminatedNCT04567251
• Gait Training Through a Novel Over-ground Wearable Robotic System in People With Pyramidal HemisyndromesActive, not recruitingNCT04559724Not applicable
• Seizure Control as a New Metric in Assessing Efficacy of Tumor Treatment in Patients With Low Grade GliomaActive, not recruitingNCT04553757
• A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast CancerActive, not recruitingNCT04538742Phase 1/2
• Evaluation of Changes in Brain Connectivity After Tumor ResectionCompletedNCT04536142
• Dosimetric Validation of Scans Generated by GAN From Pre-therapeutic MRI in Stereotactic Cerebral RadiotherapyCompletedNCT04525053
• RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System TumorsTerminatedNCT04525014Phase 1
• Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain CancerWithdrawnNCT04521946Phase 1
• Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain MetastasisActive, not recruitingNCT04516070Phase 2
• TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain MetastasesWithdrawnNCT04512261Phase 1/2
• Tislelizumab Combined With Pemetrexed/ Carboplatin in Patients With Brain Metastases of Non-squamous NSCLCCompletedNCT04507217Phase 2
• Preoperative Stereotactic Radiosurgery for Brain MetastasesCompletedNCT04503772Phase 2
• Controlling Coordination After Childhood Cerebellar Cancer, a Pilot StudyStatus unknownNCT04501731
• The Accuracy of Brain Biological Electrical Impedance Tomography Screen for Supratentorial TumorsStatus unknownNCT04490954Not applicable
• Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid TumorsCompletedNCT04487236Phase 1
• HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade GliomaWithdrawnNCT04482933Phase 2
• A Phase 1-2 Study of ST101 in Patients With Advanced Solid TumorsActive, not recruitingNCT04478279Phase 1/2
• Pre- Versus Post-operative SRS for Resectable Brain MetastasesTerminatedNCT04474925Phase 3
• Perioperative Evaluation of Cerebellar TumorsActive, not recruitingNCT04463979
• 18F-fluciclovine PET/MRI Imaging for the Detection of Tumor Recurrence After Radiation Injury to the BrainTerminatedNCT04462419
• Accelerated Checkpoint Therapy for Any Steroid Dependent Patient With Brain MetastasesTerminatedNCT04461418Phase 2
• Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRITerminatedNCT04460495Not applicable
• Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various CancersActive, not recruitingNCT04459273Phase 1
• Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit StudyCompletedNCT04456140Phase 1
• Intracranial Hydatid CystCompletedNCT04454268Not applicable
• Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRTCompletedNCT04452084Phase 2
• Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM PatientsCompletedNCT04446416Not applicable
• Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072SCompletedNCT04430842Phase 1
• Single vs Multi-fraction SRS Patients on ImmunotherapyWithdrawnNCT04427228Phase 2
• X-396 (Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain MetastasesStatus unknownNCT04415320Phase 2
• Cytoprotective Effect and Clinical Outcome of Perioperative Proesterone in Brain TumorsStatus unknownNCT04414020Phase 1
• Hyperlactatemia During and After TumorcraniotomyCompletedNCT04410315
• Safety Study of Pritumumab in Brain CancerCompletedNCT04396717Phase 1
• GM1 Prophylaxis for WBRT Related Cognitive DysfunctionTerminatedNCT04395339Phase 3
• Research of Biomarkers of Response to Proton Beam Therapy in Pediatric and Adult Patients.CompletedNCT04367779
• Intra-operative Variation in Size of Brain Tumors After CraniotomyCompletedNCT04365647
• Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)Active, not recruitingNCT04365374Phase 3
• Evaluation of the Best Treatment in Terms of Quality of Life for Patients Having a Brain MetastasisStatus unknownNCT04358666Not applicable
• National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 RegistryCompletedNCT04351035
• Bevacizumab Combined With Fractionated Stereotactic Radiotherapy for 1 to 10 Brain Metastases From NSCLCCompletedNCT04345146Phase 2
• Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy SurgeryWithdrawnNCT04344626Not applicable
• Phase I Study of Marizomib + Panobinostat for Children With DIPGTerminatedNCT04341311Phase 1
• An Open Label, Multicenter, Phase II Study of Dacomitinib for EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) With Brain MetastasesStatus unknownNCT04339829Phase 2
• Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC PatientsCompletedNCT04338867Phase 2
• WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain TumorsCompletedNCT04334863Phase 1

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