Anemia, Sickle Cell: all 1,125 studies
Page 7 of 12. Open to participants first (238), then studies with results posted, then the rest; newest registration first within each.
- Retrospective Real World Oxbryta® Data Collection and Analysis StudyCompletedNCT04930328
- PET Imaging of Vaso-Occlusive Crisis (VOC) in SCDCompletedNCT04925492Phase 1
- Health Literacy - Neurocognitive Screening in Pediatric SCDCompletedNCT04917783Not applicable
- Observational Prospective Study Measuring the Impact of the Use of a Hypnotic Script Associated With Virtual Reality on the Pain of the Child's Sickle Cell During a Vaso-occlusive CrisisCompletedNCT04917120Not applicable
- A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD).CompletedNCT04912869Phase 1
- Prevalence and Pathophysiology of Systemic Arterial Pressure Abnormalities in Childhood Sickle Cell DiseaseStatus unknownNCT04911049
- Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease PainCompletedNCT04906447Phase 2
- Distracting Through Procedural Pain and DistressCompletedNCT04892160Not applicable
- Pilot Evaluation of a Motivational Interviewing Intervention Targeting Adherence Behaviors in Youth With Sickle Cell DiseaseCompletedNCT04877054Not applicable
- Evaluation of Left Ventricular Function by Speckle Tracking Echocardiography in Patient Hospitalised in Intensive Care Unit for Vaso-occlusive CrisisStatus unknownNCT04864041
- A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)Active, not recruitingNCT04853576Phase 1/2
- L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)TerminatedNCT04852172Phase 1/2
- Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell AnaemiaCompletedNCT04844099Phase 3
- Study of Biological Markers in Children With Sickle Cell DiseaseStatus unknownNCT04839159Not applicable
- Peripheral Blood Stem Cell Collection From Patients With Sickle Cell Disease (SCD) Using PlerixaforWithdrawnNCT04817345Phase 2
- Stroke Prevention in Young Adults With Sickle Cell AnemiaActive, not recruitingNCT04808778
- The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern NigeriaCompletedNCT04800809
- Sickle Cell Disease, Neurocognitive Disorders, Social ParticipationCompletedNCT04793854
- Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe HemoglobinopathiesWithdrawnNCT04776850Early Phase 1
- Fitness Trial in Adults With Sickle Cell Disease (SCD Fit): A Feasibility StudyCompletedNCT04772391Not applicable
- Evaluation of Virtual Reality to Save Morphinic in the Treatment of Vaso-occlusive Seizures of Sickle Cell Patients Consulting in the Emergency RoomCompletedNCT04756375Not applicable
- Interest of Nutritional Care of Children With Sickle Cell Disease on Bone Mineral Density and Body CompositionCompletedNCT04754711Not applicable
- Hydroxyurea Therapy for Neurological and Cognitive Protection in Pediatric Sickle Cell Anemia in Uganda ( BRAINSAFE-II )CompletedNCT04750707Phase 3
- Expanded Access Protocol for Adults and Pediatric Patients With Sickle Cell Disease Who Have No Alternative Treatment OptionsNo longer availableNCT04724421
- ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension StudyActive, not recruitingNCT04707235
- Physical Rehabilitation in Sickle Cell AnemiaStatus unknownNCT04705792Not applicable
- Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, FranceCompletedNCT04694976
- The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.CompletedNCT04691323Not applicable
- An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell DiseaseCompletedNCT04688411Not applicable
- Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease PatientsCompletedNCT04684381Phase 4
- Home-based Assessment of PRO Measures in SCD Using A Smartphone App Platform: A Feasibility StudyCompletedNCT04678037Not applicable
- Obesity in Pediatric Sickle Cell Disease: A New PhenomenonCompletedNCT04676113
- Adherence to HU and HRQOL in Patients With Sickle Cell Disease: An Intervention Study Using HU-Go AppCompletedNCT04675645Not applicable
- Evaluation of Therapeutic Adherence to Inciting Spirometry in Sickle Cell PatientsCompletedNCT04667325
- Vitamin D Supplementation in Children With Sickle Cell DiseaseStatus unknownNCT04662476Not applicable
- Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCTCompletedNCT04629430Not applicable
- A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)Active, not recruitingNCT04624659Phase 3
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of MitapivatActive, not recruitingNCT04610866Phase 1/2
- Utilizing A Single Session Problem-Solving Intervention With Caregivers of Pediatric Patients Receiving Chronic Transfusion to Treat Sickle Cell DiseaseCompletedNCT04606160Not applicable
- US Phase I Study of ECT-001-CB in Patients With Sickle-Cell DiseaseWithdrawnNCT04594031Phase 1
- Safety, Tolerability and Pharmacokinetics of FTX-6058CompletedNCT04586985Phase 1
- Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell DiseaseCompletedNCT04584528Not applicable
- Voxelotor Sickle Cell Exercise StudyCompletedNCT04581356Phase 4
- SELF-BREATHE RCT for Chronic BreathlessnessCompletedNCT04574050Not applicable
- Medication Adherence and Non-adherence in Adults With Rare DiseaseWithdrawnNCT04541875
- A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell DiseaseCompletedNCT04536792Phase 1
- A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell DiseaseCompletedNCT04484272Not applicable
- Isoquercetin in Sickle Cell AnemiaWithdrawnNCT04474626Phase 2
- Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD)TerminatedNCT04443907Phase 1
- Living With Sickle Cell Disease in the COVID-19 PandemicCompletedNCT04417673
- Evaluation of Impact of Disease on Quality of Life, Education and Socio-professional Integration of Adults and Parents of Children Living with Sickle- Cell Disease in FranceCompletedNCT04413539
- Metabolic and Hemodynamic Reserve in Pediatric SCAActive, not recruitingNCT04406818Not applicable
- Preliminary Feasibility and Efficacy of Behavioral Intervention to Reduce Pain-Related Disability in Pediatric SCDCompletedNCT04388241Not applicable
- Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell AnemiaCompletedNCT04380610
- Reduced Intensity Transplantation for Severe Sickle Cell DiseaseActive, not recruitingNCT04362293Phase 2
- Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell TraitCompletedNCT04349189
- A Voxelotor for Sickle Cell Anemia Patients at Highest Risk for Progression of Chronic Kidney DiseaseTerminatedNCT04335721Phase 1/2
- Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell AnemiaCompletedNCT04301336Phase 2/3
- Prevalence of Osteoporosis in Sickle Cell DiseaseCompletedNCT04299594
- A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell DiseaseActive, not recruitingNCT04293185Phase 3
- Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease.WithdrawnNCT04293172Phase 3
- Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell DiseaseCompletedNCT04285827Phase 1
- Is the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative ComplicationsStatus unknownNCT04264871
- Dose Escalation Study of PF-07209326 in Healthy Participants and Participants With Sickle Cell DiseaseCompletedNCT04255875Phase 1
- Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.CompletedNCT04244240
- Biological, Genetic and Environmental Involved in the Complications of Sickle Cell DiseaseStatus unknownNCT04205123
- Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia PatientsStatus unknownNCT04191213Phase 2/3
- Sickle Cell Uric Acid (SCUA) - Cohort RepositoryCompletedNCT04190888
- Qualitative Survey of Potential Exercise Activity in Adults With Sickle Cell Anemia (SCA)CompletedNCT04181944Not applicable
- Dissemination and Implementation of Stroke Prevention Looking at the Care EnvironmentCompletedNCT04173026Not applicable
- Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PEDTerminatedNCT04150757Phase 3
- To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell DiseaseCompletedNCT04134299Not applicable
- Acupuncture for Pain in Sickle Cell DiseaseCompletedNCT04122378Not applicable
- Nonpharmacological Approaches and Parental Education in Children With Sickle Cell DiseaseCompletedNCT04121247Not applicable
- Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell AnemiaCompletedNCT04109820Not applicable
- CSL200 Gene Therapy in Adults With Severe Sickle Cell DiseaseTerminatedNCT04091737Phase 1
- Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE)Active, not recruitingNCT04084080Phase 3
- Algorithm for Apherisis Monitoring and Prescription Assistance in Sickle Cell Patients (ALGODREP)CompletedNCT04076683Not applicable
- FOCUS for Pediatric Sickle Cell Disease and CancerStatus unknownNCT04075877Not applicable
- Autonomic Nervous System and Sickle Cell DiseaseCompletedNCT04062409
- Deferoxamine for Sickle Cell Chronic Leg Ulcer TreatmentWithdrawnNCT04058197Phase 1/2
- Coordinated HEalthcare for Complex KidsCompletedNCT04057521Not applicable
- An Extension Study of IMR-687 in Adult Patients With Sickle Cell AnemiaActive, not recruitingNCT04053803Phase 2
- Comparison of Allogeneic Matched Related Haematopoietic Stem Cell Transplantation After a Reduced Intensity Conditioning Regimen With Standard of Care in Adolescents and Adults With Severe Sickle Cell DiseaseStatus unknownNCT04046705Phase 3
- Impact on the Length of Stay in Incentive Spirometry and Pain in the Decompensation of Sickle Cell Disease: .CompletedNCT04041180
- Near Infrared Spectroscopy in Sickle Cell Pediatric PatientsWithdrawnNCT04031521
- Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell TransplantationActive, not recruitingNCT04018937Phase 2
- Neuropathic Pain in Jamaicans With Sickle Cell DiseaseCompletedNCT04015401
- Folic Acid Supplementation in Children With Sickle Cell DiseaseCompletedNCT04011345Not applicable
- Ketamine Infusion for Sickle Cell Pain CrisisWithdrawnNCT04005209Phase 4
- Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell AnaemiaStatus unknownNCT04001907Not applicable
- iPeer2Peer Program for Youth With Sickle Cell DiseaseActive, not recruitingNCT03989986Not applicable
- DREPAMASSE Study - Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass SpectrometryCompletedNCT03985501
- Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell DiseaseTerminatedNCT03978156Phase 1
- Study of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell DiseaseCompletedNCT03977532Not applicable
- TAPS2 Transfusion Antenatally in Pregnant Women With SCDStatus unknownNCT03975894Phase 2
- Implications of a Paediatrician-psychologist Tandem for Sickle Cell Disease Care and Impact on Cognitive FunctioningCompletedNCT03975699
- Safety and Efficacy of Gene Therapy of the Sickle Cell Disease by Transplantation of an Autologous CD34+ Enriched Cell Fraction That Contains CD34+ Cells Transduced ex Vivo With the GLOBE1 Lentiviral Vector Expressing the βAS3 Globin Gene in Patients With Sickle Cell Disease (DREPAGLOBE)CompletedNCT03964792Phase 1/2
- Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle NephropathyCompletedNCT03958643
- Sickle Cell Disease, HemechipCompletedNCT03948516