Anemia, Aplastic: all 348 studies

Page 2 of 4. Open to participants first (100), then studies with results posted, then the rest; newest registration first within each.

• JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow FailureActive, not recruitingNCT05998408Phase 1/2Results posted
• Study of the Selective GlyT1 Inhibitor Bitopertin for Steroid-Refractory Diamond-Blackfan AnemiaCompletedNCT05828108Phase 1/2Results posted
• Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 DepletionActive, not recruitingNCT05236764Not applicableResults posted
• A Study to Assess Efficacy and Safety of PF-06462700 in Japanese Participants With Aplastic AnemiaCompletedNCT04350606Phase 3Results posted
• Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplastic AnemiaCompletedNCT04328727Phase 2Results posted
• Study Assessed the Safety and Efficacy of Eltrombopag in Chinese Refractory or Relapsed Severe Aplastic Anemia (SAA) Subjects.CompletedNCT03988608Phase 2Results posted
• Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical StudyTerminatedNCT03733249Phase 1/2Results posted
• Thrombosomes® in Bleeding Thrombocytopenic PatientsCompletedNCT03394755Phase 1Results posted
• Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerTerminatedNCT03333486Phase 2Results posted
• Posaconazole Prophylaxis During ATG Treatment for hMDS/AA PatientsCompletedNCT03318159Phase 2Results posted
• Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell TransplantActive, not recruitingNCT03192397Phase 1/2Results posted
• A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic AnemiaCompletedNCT03025698Phase 2Results posted
• Eltrombopag Combined With Cyclosporine as First Line Therapy in Patients With Severe Acquired Aplastic AnemiaCompletedNCT02998645Phase 2Results posted
• Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive TherapyActive, not recruitingNCT02979873Phase 2Results posted
• Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)CompletedNCT02918292Phase 2Results posted
• NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic AnemiaCompletedNCT02833805Phase 2Results posted
• Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic MalignanciesCompletedNCT02566304Phase 2Results posted
• Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A in Naive Aplastic Anemia (AA) SubjectsCompletedNCT02404025Phase 2Results posted
• Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic AnemiaCompletedNCT02224872Phase 2Results posted
• Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic AnemiaCompletedNCT02162420Not applicableResults posted
• A Study to Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic AnemiaCompletedNCT02148133Phase 2Results posted
• A Phase 2 Study to Evaluate the Efficacy and Safety of AMG531 in Aplastic AnemiaCompletedNCT02094417Phase 2Results posted
• Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell TransplantTerminatedNCT02065869Phase 1/2Results posted
• Post Transplant Cyclophosphamide (Cytoxan) for GvHD ProphylaxisCompletedNCT02065154Phase 2Results posted
• Extended Dosing With Eltrombopag for Severe Aplastic AnemiaCompletedNCT01891994Phase 2Results posted
• Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia PatientsTerminatedNCT01818726Phase 4Results posted
• Unrelated Umbilical Cord Blood (UBC)TransplantationCompletedNCT01768845Not applicableResults posted
• Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic MalignanciesCompletedNCT01760655Phase 2Results posted
• Efficacy and Safety of Eltrombopag In Patients With Severe and Very Severe Aplastic AnemiaCompletedNCT01703169Phase 2Results posted
• Eltrombopag With Standard Immunosuppression for Severe Aplastic AnemiaActive, not recruitingNCT01623167Phase 1/2Results posted
• Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic MalignanciesCompletedNCT01529827Phase 2Results posted
• Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic MalignanciesCompletedNCT01499147Not applicableResults posted
• Danazol for Genetic Bone Marrow and Lung DisordersCompletedNCT01441037Phase 1/2Results posted
• A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological MalignanciesCompletedNCT01384513Phase 2Results posted
• Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan AnemiaCompletedNCT01362595Phase 1/2Results posted
• Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative DonorCompletedNCT01350245Phase 2Results posted
• Eltrombopag for Moderate Aplastic AnemiaCompletedNCT01328587Phase 2Results posted
• Alefacept and Allogeneic Hematopoietic Stem Cell TransplantationTerminatedNCT01319851Not applicableResults posted
• Anti-thymocyte Globulin and Cyclosporine as First-Line Therapy in Treating Patients With Severe Aplastic AnemiaCompletedNCT01231841Phase 2Results posted
• Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic AnemiaCompletedNCT01193283Phase 1/2Results posted
• Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL)TerminatedNCT01191749Phase 2Results posted
• A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic AnemiaCompletedNCT01187017Phase 1/2Results posted
• Reduced Intensity Allogeneic PBSCT to Treat Hematologic Malignancies and Hematopoietic Failure StatesCompletedNCT00997386Phase 2Results posted
• Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and FludarabineCompletedNCT00987480Phase 2Results posted
• Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood CancerCompletedNCT00975975Phase 2Results posted
• Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA TreatmentCompletedNCT00944749Phase 2Results posted
• A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia PatientsCompletedNCT00922883Phase 2Results posted
• Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure DisordersCompletedNCT00856388Not applicableResults posted
• Thymoglobulin and Cyclosporine in Patients With Aplastic Anemia or Myelodysplastic SyndromeCompletedNCT00806598Phase 2Results posted
• T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic MalignanciesCompletedNCT00683046Phase 2Results posted
• A Phase II Study of Umbilical Cord Blood TransplantationTerminatedNCT00676806Phase 2Results posted
• Unrelated Cord Blood Transplant Plus a Haplo-Identical (Half-Matched), T-Cell Depleted Stem Transplant From a Related Donor for Subjects With High Risk MalignanciesCompletedNCT00673114Phase 1/2Results posted
• Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelodysplastic SyndromeCompletedNCT00604201Phase 2Results posted
• Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi AnemiaTerminatedNCT00590460Phase 1/2Results posted
• Allogeneic Stem Cell Transplant for Patients With Severe Aplastic AnemiaTerminatedNCT00578903Phase 2Results posted
• Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and HormonesTerminatedNCT00556400Phase 1/2Results posted
• Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other DisordersActive, not recruitingNCT00544115Phase 2Results posted
• Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic AnaemiaCompletedNCT00471848Phase 2Results posted
• Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAACompletedNCT00455312Phase 2/3Results posted
• Purine Analog-Based Conditioning in Patients With Severe Aplastic AnemiaCompletedNCT00427336Not applicableResults posted
• Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated DonorTerminatedNCT00393380Phase 2Results posted
• Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited DisordersTerminatedNCT00358657Phase 2Results posted
• Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow TransplantCompletedNCT00343785Phase 2Results posted
• Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301)CompletedNCT00326417Phase 1/2Results posted
• Three Immunosuppressive Treatment Regimens for Severe Aplastic AnemiaCompletedNCT00260689Phase 2Results posted
• Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory CytopeniasCompletedNCT00244010Not applicableResults posted
• Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan AnemiaCompletedNCT00229619Phase 2Results posted
• Alemtuzumab to Treat Severe Aplastic AnemiaCompletedNCT00195624Phase 2Results posted
• Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic AnemiaCompletedNCT00065260Phase 2Results posted
• NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/DisordersCompletedNCT00053989Phase 2Results posted
• Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure SyndromesCompletedNCT00004143Phase 2Results posted
• Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic CancerCompletedNCT00003816Phase 2/3Results posted
• A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow FailureTerminatedNCT00001962Phase 2Results posted
• Clinical Study of UC-MSC Combined With Immunosuppressive Agents in the Treatment of Pediatric HAAACompletedNCT07850362Not applicable
• Romiplostim N01 in the Treatment of Refractory Chemoradiotherapy-induced AAWithdrawnNCT07532408Phase 2
• CsA+EPAG/HPAG+Romiplostim N01 in the Treatment of Newly-diagnosed SAA/TD-NSAAWithdrawnNCT07523009Phase 2
• A Study of the Safety and Effectiveness of Eltrombopag in Combination With Immunosuppressive Therapy (IST) in Korean Pediatric Patients With Treatment Naïve Severe Aplastic AnemiaCompletedNCT07415083
• Multi-omics Profiling of Patients With Aplastic Anemia Before and After CD7-CAR-T TherapyActive, not recruitingNCT07139600
• UI-Romi-02; Romiplostim Added to Standard of Care for Treatment Naive and Relapsed or Refractory Severe Aplastic AnemiaWithdrawnNCT07001254Phase 2
• Real-world Outcomes of Aplastic Anemia Patients Treated With Eltrombopag: A Medical Claims Database StudyCompletedNCT06991894
• Methadone as an Alternative Treatment for Children Underdoing HSCTSuspendedNCT06940570Phase 3
• Modified Transplantation Regimen and aGVHD Prophylaxis for Severe Aplastic Anemia in the Setting of Allogeneic HSCT.CompletedNCT06837987
• Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic AnemiaActive, not recruitingNCT06752694Phase 2
• Effectiveness of Early Intervention in Transfusion Independent Aplastic Anemia: a Retrospective Medical Claims Database StudyCompletedNCT06669221
• Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAAWithdrawnNCT06424639Phase 4
• ATGAM General InvestigationActive, not recruitingNCT06039020
• CsA+ATG+AVA vs. CsA+AVA for the Treatment of Newly-diagnosed SAA in the ElderlyCompletedNCT05996393Phase 4
• Cyclophosphamide Added to Standard Immunosuppressive Therapy With Herombopag as Front-line Therapy in Patients With Severe Aplastic AnemiaActive, not recruitingNCT05975996Phase 2
• Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS StudyCompletedNCT05972577Not applicable
• Efficacy of Daratumumab to Overcome Platelet Transfusion Refractoriness in Patients with Aplastic AnemiaCompletedNCT05832216Phase 1
• Avatrombopag Combined With IST as First-line Treatment for SAAStatus unknownNCT05720234Phase 2
• A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)TerminatedNCT05600426Phase 3
• Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver FunctionStatus unknownNCT05571332Not applicable
• A Study of PEG-rhG-CSF and rhG-CSF Used for Aplastic Anemia Granulocyte DeficiencyStatus unknownNCT05531279Not applicable
• Efficacy and Safety of CSA and Avatrombopag for the Treatment of SAA in the ElderlyStatus unknownNCT05433922Not applicable
• Efficacy and Safety in Transfusion Independent Non-severe Aplastic AnemiaCompletedNCT05399732Phase 2
• Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppressive TherapyWithdrawnNCT05323617Phase 2
• Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell TransplantationCompletedNCT05298930Not applicable
• A Bioequivalence Study of Hetrombopag in Healthy SubjectsCompletedNCT05088655Phase 1
• A Trial of Hetrombopag in Healthy and Hepatic Impairment SubjectsCompletedNCT05088642Phase 1

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