Cerebral Amyloid Angiopathy clinical trials
The registry lists 37 studies for Cerebral Amyloid Angiopathy across more than 10 countries. 8 are recruiting or about to start. 30 of them are mainly about Cerebral Amyloid Angiopathy (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13. Counting its narrower condition Cerebral Amyloid Angiopathy, Familial too: 38 studies, 8 open.
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Who runs them
Centre Hospitalier Universitaire de Nīmes (7) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (4) · National Taiwan University Hospital (3) · Leiden University Medical Center (3) · Insel Gruppe AG, University Hospital Bern (2) · University Hospital, Toulouse (2) · Capital Medical University (2) · Pfizer (1)
What is being tested here
Drugs under test in Cerebral Amyloid Angiopathy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| JZP258 | 1 | 0 | 1 |
| AMDX2011P | 1 | 0 | 1 |
| Colchicine | 1 | 0 | 1 |
| Mivelsiran | 0 | 0 | 1 |
| Ponezumab | 0 | 0 | 1 |
| Minocycline | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Dec 2026A Study of AMDX-2011P in Participants With CAA · Amydis Inc.
- Aug 2027A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy · Alnylam Pharmaceuticals
- Sep 2027Stimulating Amyloid Clearance in Cerebral Amyloid Angiopathy · Leiden University Medical Center
- Oct 2027Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Who these studies take
Of the 7 Cerebral Amyloid Angiopathy studies recruiting now, 6 (86%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (57%) | 4 (57%) |
| 30 | 4 (57%) | 4 (57%) |
| 40 | 4 (57%) | 4 (57%) |
| 50 | 5 (71%) | 5 (71%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 7 (100%) | 7 (100%) |
Across all 37 studies, recruiting or not: 3% stop at 75 or younger and 0% at 65; 8% take children; 0% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 37 of 37. search them.
- Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project)RecruitingNCT06714097Not applicable1 country
- Jiedu Huayu Oral Prescription in the Treatment of Intracranial Hemorrhage Associated With Cerebral Amyloid AngiopathyRecruitingNCT07250035Phase 31 country
- Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy.RecruitingNCT069332121 country
- SEarchiNg biomarkErs Cerebral Amyloid Angiopathy (SENECA)RecruitingNCT042046421 country
- Stimulating Amyloid Clearance in Cerebral Amyloid AngiopathyEnrolling by invitationNCT06421532Phase 21 country
- A Study of AMDX-2011P in Participants With CAARecruitingNCT05709314Phase 21 country
- Colchicine for the Prevention of Recurrence in Cerebral Amyloid Angiopathy RElated IntraCerebral HemorrhageRecruitingNCT07026994Phase 21 country
- Prognosis of Cerebral Small Vessel DiseaseRecruitingNCT057343781 country
- A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid AngiopathyActive, not recruitingNCT06393712Phase 26 countries
- ApoE Genotyping Analysis in Patients With Suspected Non-haemorrhagic Amyloid AngiopathyCompletedNCT068090621 country
- Dilated Perivascular Spaces in the Dentate Nucleus on MRI in Patients With Hypertensive Angiopathy or Cerebral Amyloid AngiopathyCompletedNCT068888821 country
- Amyloid Imaging and Cognitive Impairment After Intracerebral HemorrhageCompletedNCT01619709Not applicable1 country
- Enpowering Progression Risk of Cerebral Amyloid AngiopathyCompletedNCT069605381 country
- Cortical Superficial Siderosis and Risk of Recurrent Intracerebral Hemorrhage in Cerebral Amyloid Angiopathy.CompletedNCT03464344Not applicable1 country
- Brain Hemorrhage and Functional Outcome in Stroke Patients With CAA Features on Pre-thrombolysis MRI Treated With Intravenous Thrombolysis (Thrombolysis in CAA) ( Thromb in CAA )CompletedNCT055651441 country
- Cerebellar Superficial Siderosis in Cerebral Amyloid AngiopathyCompletedNCT053946361 country
- Periventricular White Matter Hyperintensities in Cerebral Amyloid Angiopathy and Hypertensive ArteriopathyCompletedNCT054868971 country
- High Frequency Imaging in Cerebral Amyloid AngiopathyActive, not recruitingNCT061288241 country
- Coach Pilot Study: Assessing Cognitive Function and Related Small Vessel Disease Markers After Intracerebral HemorrhageTerminatedNCT054991691 country
- MRI-markers to Monitor Small Vessel Disease Dynamics in the Prognosis of Small Vessel Disease-associated, Cerebrovascular EventsStatus unknownNCT057732351 country
- Antibiotics Against Amyloid AngiopathyStatus unknownNCT05680389Phase 1/21 country
- Safety and Efficacy of Remote Ischemic Conditioning on Cerebral Amyloid Angiopathy. (RIC-CAA)Status unknownNCT05207475Not applicable1 country
- Balance Eyesight and Muscle Tension in the Cervical Spine in Cerebral Amyloid AngiopathyCompletedNCT050821941 country
- Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD)CompletedNCT03824197Not applicable1 country
- Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral HemorrhageStatus unknownNCT04757597Not applicable1 country
- Detailed Clinical and MRI Characteristics in Primary Non-traumatic Convexity Subarachnoid Haemorrhage Elderly Patients.CompletedNCT048258081 country
- Multimodal Biomarkers for Diagnosis and Prognosis in CAAStatus unknownNCT03969732Phase 31 country
- the Safety and Efficacy of Antiplatelet Therapy in Patients of CAAStatus unknownNCT04654026
- Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial HemosiderosisWithdrawnNCT02664571Not applicable1 country
- MRI-visible Enlarged Perivascular Spaces and the Alteration of Lymphatic Drainage System in CAAStatus unknownNCT04604587Phase 31 country
- Application of Amyloid PET in Cerebral Amyloid AngiopathyCompletedNCT03542656Phase 31 country
- Use Lay Language. CAA-ri : a Series of 28 PatientsTerminatedNCT03187886
- Superficial Siderosis in Patients With Suspected Cerebral Amyloid AngiopathyStatus unknownNCT018566991 country
- Study Evaluating the Safety,Tolerability and Efficacy of PF-04360365 in Adults With Probable Cerebral Amyloid AngiopathyCompletedNCT01821118Phase 25 countries
- Methods of Etiological Diagnosis of Cerebral Amyloid AngiopathyStatus unknownNCT023614111 country
- F-18-AV-45 Uptake, Spot Sign Presence and Cerebral Amyloid Angiopathy (CAA) in Primary Intracranial Hemorrhage (ICH)WithdrawnNCT013828491 country
- Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid AngiopathyCompletedNCT00056238Phase 21 country