Amyloid Neuropathies clinical trials
The registry lists 15 studies for Amyloid Neuropathies across more than 10 countries. 3 are recruiting or about to start. 4 of them are mainly about Amyloid Neuropathies (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its 2 narrower conditions too, such as Amyloid Neuropathies, Familial: 244 studies, 112 open.
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Who runs them
Alnylam Pharmaceuticals (6) · CENTOGENE GmbH Rostock (2) · University of Sao Paulo General Hospital (1) · Hospital Italiano de Buenos Aires (1) · Intellia Therapeutics (1) · AstraZeneca (1) · Assistance Publique Hopitaux De Marseille (1) · University Hospital, Antwerp (1)
What is being tested here
Drugs under test in Amyloid Neuropathies studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Jul 2027A Phase 3 Study of NTLA-2001 in ATTRv-PN · Phase 3 · Intellia Therapeutics
Who these studies take
Of the 2 Amyloid Neuropathies studies recruiting now, 1 (50%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (50%) | 1 (50%) |
| 18 | 2 (100%) | 2 (100%) |
| 30 | 2 (100%) | 2 (100%) |
| 40 | 2 (100%) | 2 (100%) |
| 50 | 2 (100%) | 2 (100%) |
| 65 | 2 (100%) | 2 (100%) |
| 75 | 2 (100%) | 2 (100%) |
| 85 | 2 (100%) | 2 (100%) |
Across all 15 studies, recruiting or not: 7% stop at 75 or younger and 7% at 65; 13% take children; 0% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 15 of 15. search them.
- ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)RecruitingNCT0456151812 countries
- Non-interventional Study of Patients With Transthyretin (ATTR) AmyloidosisRecruitingNCT064658106 countries
- Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral NeuropathyNot yet recruitingNCT04985734Not applicable1 country
- A Phase 3 Study of NTLA-2001 in ATTRv-PNActive, not recruitingNCT06672237Phase 36 countries
- Expanding the Biomarkers in Familial Amyloid Neuropathy: MRI and Motor Unit Estimation by Electrophysiological StudyCompletedNCT03588468Not applicable1 country
- A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid PolyneuropathyActive, not recruitingNCT05071300Phase 313 countries
- Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)Approved for marketingNCT02939820
- APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated AmyloidosisCompletedNCT01960348Phase 321 countries
- Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)WithdrawnNCT027138802 countries
- Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP)CompletedNCT017056266 countries
- A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A MutationCompletedNCT042014181 country
- Autonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart DiseaseStatus unknownNCT050879531 country
- Prevalence of Amyloidosis and Carpal TunnelWithdrawnNCT021526441 country
- A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy SubjectsCompletedNCT02797847Phase 11 country
- ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)CompletedNCT02319005Phase 39 countries