An interventional study of Dynamic Creative Arts Group in Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) and Older Adults (65 Years and Older), sponsored by Tel Aviv University. Not yet recruiting at 1 site in Israel. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2026-11-12.
Sponsored by Tel Aviv University · Not applicable, Interventional, and Treatment
Among 54 studies in Cognitive Dysfunction with a site in Israel — 6 open to participants now, 8 under way, none of them phase 3. Cognitive Dysfunction · Israel.
Among the 54 studies in Cognitive Dysfunction with a site in Israel, this one is the 16th largest by planned enrollment of the 34 interventional ones that give a count, is the only one that started in 2026, is one of 23 with no phase, and was the 54th registered.
3,872 studies on the registry are indexed under Cognitive Dysfunction; 1,119 are open to participants now.
Browse Cognitive Dysfunction studies →6 of the 54 studies in Cognitive Dysfunction with a site in Israel are open now. Recruiting first, the newest first:
Hadassah Medical Organization · Sites in Israel
Ages 18+ · Women only
Rutgers, The State University of New Jersey · Sites in Israel
Ages 60–90
Assaf-Harofeh Medical Center · Sites in Israel
Ages 60–85
Rambam Health Care Campus · Sites in Israel
Ages 18+ · Healthy volunteers
Hadassah Medical Organization · Sites in Israel
Ages 65+
A study can be open while its sites in Israel have not opened yet or have stopped. Only those recruiting at a site in Israel →
Of the 750 Cognitive Dysfunction studies recruiting now, 362 (48%) set no upper age limit and 143 (19%) stop at 75 or younger; 46 take children under 18; 259 take healthy volunteers.
This study: 65 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
54 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 2 · Phase 2 6 · Phase 3 3 · Phase 4 1
First in 2000; this study’s year is marked. 1 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 50 is below the median of 64 across 2,794 interventional studies indexed under Cognitive Dysfunction.
Median enrollment 50 across the 34 interventional studies, 99 across the 20 observational. Of the 23 that completed or were terminated, 5 (22%) have results posted.
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12 of 54 have an industry lead sponsor. The 10 most frequent:
Tel Aviv University is the lead sponsor of 101 studies on the registry; 27 are open to participants now.
Tel Aviv University has 3 studies filed under Cognitive Dysfunction — fewer than ten, so there is no comparison to draw.
3 of the studies in Cognitive Dysfunction with a site in Israel that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07287852Hadassah Medical OrganizationA Pilot Study to Examine the Effect of Egb761 on Plasma Biomarker Levels and on Cognitive Function in Patients With MCI | 2026-12 |
| NCT07596186Soroka University Medical CenterPredict Early Cognitive Changes in a Healthy Elderly Population by Passively Recording Sensor Data From Mobile Devices | 2027-01-01 |
| NCT07591857Hadassah Medical OrganizationThe Computerized Retraining and Functional Treatment - Group Intervention | 2027-10 |
Add all 3 to your calendar (.ics) → With an account.
Among the 54 studies in Cognitive Dysfunction with a site in Israel, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The goal of this study is to investigate whether a dynamic group intervention that combines conversation and creative arts can reduce loneliness and support well-being and quality of life among older adults experiencing subjective or mild cognitive impairment.
The study will also explore how participants connect with one another, express emotions, and develop relationships during the group sessions.
Fifty older adults aged 65 and older, with subjective or mild cognitive impairment, will take part in the study.
Participants will:
Attend 10-group sessions that combine open conversations combined with creative arts, such as art, music, movement, and drama. Group sessions will be video-recorded to help researchers study participants' interactions and processes in the group.
Complete questionnaires about loneliness, well-being, and quality of life at Baseline, Pre, Post the intervention and follow-up.
Answering questions about how they feel before and after selected sessions.
Participate in an interview and share their experiences of participating in the group.
Researchers will also observe group interactions to better understand how relationships and emotional expression develop during the sessions.
Older adults experiencing early cognitive decline may face challenges that go beyond memory difficulties. Changes in word-finding, communication, and thinking may affect their confidence, social participation, and relationships with others. Some may feel embarrassed, become less involved in social activities, or find it difficult to share their concerns and emotions. These experiences may contribute to loneliness and reduced psychological well-being and quality of life.
At this early stage of cognitive decline, many older adults continue to live independently and maintain their everyday activities. However, they may experience uncertainty about the changes they notice and worry about the future. Opportunities for meaningful relationships, emotional expression, and a sense of belonging may be especially important during this period.
Most existing interventions for older adults with subjective or mild cognitive impairment focus on maintaining or improving cognitive abilities. Less attention has been given to their emotional and interpersonal needs, particularly the need to share personal experiences, feel understood, and develop meaningful connections with others.
A dynamic group intervention may provide an opportunity to address these needs through sharing emotions, exploring interpersonal relationships, and interacting with others in the here and now. However, difficulties with verbal expression and reflection may make participation in traditional dynamic groups challenging for some older adults with cognitive decline.
Integrating creative arts into a dynamic group offers additional ways to communicate, express emotions, and connect with others. Visual art, music, movement, and drama can support participation without relying solely on words. The creative activities are not the main therapeutic focus but serve as a way to encourage emotional expression, shared experiences, and interpersonal connections.
Study Design and Procedures
The study uses a repeated-measures design without a separate control group. Fifty participants will take part in five rounds of groups with \~10 participants per group.
Assessments will take place at four time points: baseline, approximately one month before, pre-intervention, post-intervention and follow-up, four weeks later.
The period before the intervention will serve as a comparison period to examine changes that occur without the group intervention.
Immediate psychological well-being will also be assessed before and after sessions # 2, 4, 7, and 9.
Understanding Emotional and Interpersonal Processes In addition to examining changes in loneliness, psychological well-being, and quality of life, the study will explore how participants engage with others and express emotions during the group sessions.
All sessions will be video-recorded. Selected video segments will be analyzed to identify emotional behaviors and interpersonal interactions, including facial expressions, tone of voice, gestures, body movements, and verbal communication.
The study will also examine group engagement and perceived group support, and explore whether these processes are associated with changes in loneliness and psychological well-being.
Participants' Experiences Following the intervention, individual interviews will explore participants' experiences, including meaningful moments, relationships with other group members, emotional expression, and feelings of belonging.
The study aims to better understand not only whether this intervention can support older adults with early cognitive decline, but also how emotional expression and interpersonal connections may contribute to their well-being.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
1) Participants with scores ≤ 19 in the , will not be included.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The intervention consists of 10 sessions, held twice a week, in closed groups of 8-10 older adults with subjective or mild cognitive impairment. Each session lasts 90 minutes and includes an opening check-in, a warm-up activity, a semi-structured creative activity followed by dynamic group discussion, and a closing ritual. Creative arts, including visual art, music, movement, and drama, are used to support emotional expression and interpersonal connections. Sessions address personal identity, meaningful relationships, family, life experiences, group belonging, and separation. The facilitator encourages participants to share experiences, explore emotions, respond to one another, and reflect on relationships within the group. The intervention emphasizes here-and-now interactions, mutual support, and the development of meaningful connections.
Behavioral: Dynamic Creative Arts Group
A dynamic group intervention integrating creative arts for older adults with subjective or mild cognitive impairment. The intervention includes 10 sessions, held twice weekly, lasting 90 minutes each. Sessions combine group discussions with visual art, music, movement, and drama. The therapeutic focus is on here-and-now interactions, emotional expression, interpersonal learning, and the development of meaningful relationships. Creative activities provide additional verbal and nonverbal ways to communicate, share experiences, and connect with others. The facilitator encourages mutual support, reflection, and a sense of belonging within the group.
Also known as: Dynamic group with creative arts
changes in scores of the Three-Item Loneliness Scale
Perceived loneliness will be assessed using the Three-Item Loneliness Scale . The scale measures how often participants feel a lack of companionship, left out, or isolated from others. Each item is rated on a 3-point scale (1 = Hardly Ever, 2 = Some of the Time, 3 = Often). Total scores range from 3 to 9, with higher scores indicating greater perceived loneliness. The questions will be read aloud to participants.
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in the lubben social network scale
Social interaction will be measured by the Lubben Social Network Scale . This is a short measure of social isolation and perceived social support in older adults . It includes three items assessing kinship (family) ties and three items of nonkin (friendship) ties. Scores range from 0-30. A clinical cut off score of less than 12 indicates risk for social isolation.
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in the Actual social interaction
A non-formal observation will focus on actual social interaction of the participants. Verbal and nonverbal behaviors, engagement with other members of the center or staff will be considered Social interaction.
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in the Positive and Negative Affect Schedule short form
A 10 item self-report measure of positive and negative affect, representing the affective component of subjective well-being. Items are rated from 1-never to 5-always, with separate scores for positive and negative affect (range: 5-25), with higher scores indicating greater levels of the specific affect.
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in Satisfaction With Life Scale
The Satisfaction With Life Scale is a self-report measure, assessing global life satisfaction. Each of the 5 items is rated on a 7 point Likert scale ranging from 1 (strongly disagree) to 7 (strongly agree), total scores range from 5-35, higher scores indicate better life satisfaction.
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in the utilization of health services
The number of doctor visits or general visits to primary care clinic within the last two weeks (collected by self-report ).
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in the Subjective Health Rating
The question asked is: "In general, would you say your health is: excellent/very good/good/fair/poor?". This single item, self-rated, health measure is widely used in older adults studies and has demonstrated strong validity.
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in the Bath Assessment of Subjective Quality of Life in Dementia
Subjective quality of life will be assessed using the Bath Assessment of Subjective Quality of Life in Dementia . This 14-item self-report questionnaire assesses two domains: life satisfaction and feelings of positive quality of life. Items are rated on a 5-point scale from 0 to 4. Scores are transformed to a 0-100 scale, with higher scores indicating better subjective quality of life.
Time frame: Baseline, pre-intervention ( 4 weeks after Baseline), post-intervention (5 weeks later) - and 4-week follow-up
changes in the immediate psychological wellbeing
The Canterbury Wellbeing Scale is a short, self-report, visual analogue scale to assessing subjective wellbeing 'in the moment' of people with cognitive decline. It consists of five subscales (happy/sad, well/unwell, interested/bored, confident/not confident, optimistic/not optimistic) rated 0-100, with a total score ranging from0 to 500). Higher scores means better wellbeing.
Time frame: The intervention will include 10 group sessions, each session 60-90 minutes long, (twice a week). Outcome will be measured before and after sessions 2, 4, 7 and 9 .
changes in the perceived Group Processes
Perceived group processes will be assessed using a 7-item questionnaire developed for this study, based on existing measures of group cohesion, therapeutic alliance, and Yalom's therapeutic factors in group psychotherapy. The questionnaire assesses participants' perceptions of relationships with other group members and the facilitator, emotional sharing, interpersonal learning, and sense of belonging. Each item is rated on a 5-point agreement scale, from strongly disagree (1) to strongly agree (5). Higher scores indicate more positive perceptions of group processes.
Time frame: The intervention will include 10 group sessions, each session 60-90 minutes long (twice a week). Outcome will be measured after sessions 2, 4, 7 and 9.
Demographic and functional data
A study-specific questionnaire will collect demographic and functional information, including age, sex, country of birth, marital status, education, living arrangements, and previous occupation. Additional questions address self-reported vision, hearing, mobility, independence in basic activities of daily living, and using formal care support. Two questions assess subjective memory decline and related concerns.
Time frame: Baseline
The Montreal Cognitive Assessment
The assessment will be used as an objective cognitive screening tool; scores of 26 and above will indicate Subjective Cognitive Impairment, whereas scores ranging from 19-25 will be considered Mild Cognitive Impairment and scores of 18 and below will be considered severe cognitive deficit.
Time frame: baseline
Participant Satisfaction and Perceived Benefits of the Group Intervention
Participant satisfaction and perceived benefits will be assessed using a questionnaire developed for this study. It includes 13 items rated on a 5-point scale, assessing overall satisfaction, comfort with emotional sharing, perceived changes in mood and confidence, sense of belonging, interpersonal connections, perceived reduction in loneliness, facilitator support, and the contribution of creative arts to emotional expression. Additional open-ended questions explore participants' experiences, preferences, and suggestions for improvement.
Time frame: At post-intervention (following completion of 10-sessions, each session 60-90 minutes long).
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Oct 2026; primary completion for May 2028, 19 months later.
Of 1,442 non-industry interventional studies with no phase under Cognitive Dysfunction, half reached primary completion within 27 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 51. This study's planned 19 months is below that.
Counting every sponsor, half of 1,511 studies reached it within 27 months; a quarter within 12 and three quarters within 50.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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