An interventional study of Supine position nasal lavage and Semi-sitting position nasal lavage in Acute Upper Respiratory Tract Infections, Nasal Obstruction and Bronchiolitis, sponsored by Hospital Universitario La Paz. Not yet recruiting at 1 site in Spain. Open to participants aged 1 Day to 2 Years. Per ClinicalTrials.gov, last updated 2026-11-06.
Sponsored by Hospital Universitario La Paz · Not applicable, Interventional, and Treatment
Acute upper respiratory tract infections are the primary cause of pediatric visits and hospitalizations in young children. Nasal congestion and mucus accumulation often cause discomfort, feeding difficulties, and respiratory distress in infants. Nasal lavage using normal saline solution is widely recommended to clear upper airways; however, there is limited evidence regarding the optimal patient posture during irrigation.
This study aims to determine whether patient position-supine (lying on the back) versus sitting (tilted 10 degrees forward)-improves the effectiveness of nasal cavity clearance in children aged 0 to 2 years.
A randomized, parallel, age-stratified clinical trial will be conducted at Pediatric Emergency Department and in Pediatric Hospitalization at Universitary La Paz hospital. Participants will be pediatric patients with mild-to-moderate upper respiratory symptoms requiring nasal lavage as part of their routine care.
173 studies on the registry are indexed under Nasal Obstruction; 31 are open to participants now.
This study's planned enrollment of 145 is above the median of 70 across 139 interventional studies indexed under Nasal Obstruction.
Browse Nasal Obstruction studies →Hospital Universitario La Paz is the lead sponsor of 56 studies on the registry; 20 are open to participants now.
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Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
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Patients placed in supine position with the headboard flat and head turned to the side during normal saline nasal irrigation
Procedure: Supine position nasal lavage
Patients placed in a semi-sitting position, tilted 10 degrees forward and swaddled in a sheet during normal saline nasal irrigation
Procedure: Semi-sitting position nasal lavage
Lying position nasal irrigation
Seated nasal irrigation 10 degrees forward
Effectiveness of nasal cavity cleaning according to the investigator
Visible expulsion of mucus or normal saline solution through nostril after irrigation
Time frame: Periprocedural
Physiological parameters: Oxygen saturation
Changes in pulse oximetry oxygen saturation percentage
Time frame: Periprocedural
Clinical severity assessed by the modified TAL score
Evaluation of respiratory distress using the validated modified TAL score (ranging from 0 to 12 points)
Time frame: Baseline and immediately after the intervention
Incidence and type of adverse effects
Occurrence and classification of adverse effects experienced during or immediately after the technique, such as nasal bleeding (epistaxis), transient apnea, cyanosis, vomiting, or coughing.
Time frame: Periprocedural
Physiological parameters: heart rate
Changes in patient heart rate
Time frame: Baseline and immediately after the intervention
Physiological parameters: respiratory rate
Changes in patient respiratory rate
Time frame: Baseline and immediately after the intervention
Plan to share: No
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Hospital Universitario La Paz