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Not yet recruitingNCT07260643SiLaC-LaPazUpdated Dec 9, 2025

SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study.

An observational study in Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess and Pilonidal Sinus, sponsored by Hospital Universitario La Paz. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-12-09.

Sponsored by Hospital Universitario La Paz · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
40
Ages
18 Years and older
Sex
All
01

Study summary

Pilonidal sinus disease (PSD) is a chronic inflammatory condition of the sacrococcygeal region that frequently affects young adults, often causing pain, drainage, and recurrent infection. Traditional surgical approaches such as wide excision or flap techniques may result in prolonged healing times, relevant postoperative pain, and recurrence rates up to 20-30%.

The SiLaC (Sinus Laser-Assisted Closure) technique is a minimally invasive procedure that uses a 1470-nm diode laser fiber to ablate the sinus epithelium and induce concentric contraction of the tract. International studies have reported promising results with faster recovery, minimal wound care, and low morbidity.

This prospective single-center cohort study aims to evaluate the clinical outcomes and perceived recovery time of adult patients treated with the SiLaC® technique at Hospital Universitario La Paz (Madrid, Spain). The main outcome is the total recovery time perceived by patients after surgery. Secondary outcomes include postoperative complications, recurrence rate, pain intensity, need for wound care, and patient satisfaction. Data will be collected from medical records and structured follow-up interviews.

Read the detailed description

Pilonidal sinus disease (PSD) represents a chronic, recurrent inflammatory disorder of the natal cleft that primarily affects young males. It is associated with risk factors such as obesity, prolonged sitting, and deep gluteal folds. Although not life-threatening, PSD significantly affects quality of life and healthcare resources due to recurrences and delayed wound healing.

Conventional surgical approaches, including excision with secondary healing or flap reconstruction (Limberg, Karydakis, Bascom), often require prolonged recovery and intensive postoperative care. Minimally invasive alternatives have been developed to improve patient recovery and reduce morbidity. Among them, the SiLaC® (Sinus Laser-Assisted Closure) technique employs a radial 1470-nm diode laser fiber to achieve epithelial destruction and tract contraction after curettage. Early evidence suggests favorable outcomes, but robust prospective data remain scarce, especially in Spain.

This study is an ambispective, descriptive, single-center cohort conducted at Hospital Universitario La Paz, Madrid. It includes all adult patients (≥18 years) who undergo SiLaC® surgery for chronic pilonidal sinus between August 2024 and January 2026. Data will be collected retrospectively from electronic health records and prospectively during follow-up visits and structured interviews.

The primary outcome is the total recovery time perceived by the patient (days from surgery to full return to normal activities).

Secondary outcomes include postoperative complications (minor or major), pain intensity (EVA 0-10), wound infection, recurrence within 6 months, patient satisfaction (0-10 scale), and number of wound care visits.

Data will be anonymized and analyzed descriptively using R software (version 4.3.1). Normality will be assessed with the Kolmogorov-Smirnov test; comparisons will use Student's t-test, Mann-Whitney, ANOVA, or Chi-square as appropriate. A significance level of p \< 0.05 will be applied.

The study poses no additional risk, as SiLaC® is part of routine surgical practice. Ethical approval will be obtained from the Institutional Ethics Committee (CEIm of Hospital Universitario La Paz / IdiPAZ). Patient confidentiality will be guaranteed under EU Regulation 2016/679 and Spanish Law 3/2018.

02

Conditions studied

  • Pilonidal Sinus Disorder
  • Pilonidal Cyst Without Abscess
  • Pilonidal Sinus
  • Pilonidal Cysts
  • Pilonidal Sinus Treatment

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Keywords

  • Pilondal sinus
  • Pilonidal Cyst
  • SilaC
  • laser-assisted closure
  • minimal invasive surgery
  • coloproctology
  • postoperative recovery
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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients (≥18 years) with chronic pilonidal sinus disease who undergo laser-assisted closure (SiLaC®) at the Department of General and Digestive Surgery, Coloproctology Section, Hospital Universitario La Paz (Madrid, Spain). Participants will be included consecutively between August 2024 and January 2026, with a minimum follow-up of 6 months after surgery.

Inclusion criteria

  • Age ≥ 18 years.
  • Clinical diagnosis of chronic pilonidal sinus disease.
  • Undergoing surgery using the SiLaC (Sinus Laser-Assisted Closure) technique.
  • Signed informed consent for the use of anonymized clinical data for research purposes.

Exclusion criteria

Exclusion Criteria:

  • Patients with inflammatory bowel disease or complex anorectal fistulas.
  • Severe immunosuppression (active chemotherapy, high-intensity immunosuppressive therapy, uncontrolled HIV).
  • Prior pelvic radiotherapy.
  • Missing essential clinical data required for outcome assessment
04

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
40 participants (estimated)
Target follow-up
6 Months
Patient registry
Yes

Groups and cohorts

  • SilaC

    Single cohort including all consecutive adult patients operated on using the SiLaC technique between August 2024 and January 2026. Data collected retrospectively and prospectively from clinical records and follow-up interviews

    Procedure: SilaC

Interventions

  • ProcedureSilaC

    The SiLaC procedure is a minimally invasive laser technique for the management of chronic pilonidal sinus. It uses a 1470-nm diode laser radial fiber to ablate the sinus tract epithelium after curettage, inducing concentric contraction of the cavity. In this study, patients are observed as part of routine clinical care; the procedure is not assigned or modified by the study protocol.

05

What researchers measure

Primary outcomes

  1. Total perceived recovery time

    Number of days from surgery to full return to normal activities, as reported by the patient during follow-up interviews

    Time frame: 90 days

Secondary outcomes

  1. Postoperative complications

    Any adverse event (infection, seroma, hematoma, abscess, persistent pain ≥ EVA 4, reintervention).

    Time frame: 30 days

  2. Pain intensity

    Pain intensity measured using the Visual Analog Scale for pain (VAS), a 0-10 scale where 0 indicates 'no pain' and 10 indicates 'worst imaginable pain'. Higher scores reflect worse pain. Pain will be assessed at 24-48 hours and on postoperative day 7

    Time frame: 7 days

  3. recurrence

    Reappearance of drainage, fistulous orifices, or need for a new procedure after initial healing

    Time frame: 90 days

  4. Need for local wound care

    Number of dressing visits at hospital or primary care center

    Time frame: 30 days

06

Study locations

No study locations are listed for this record.

07

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be shared. The study uses anonymized clinical data stored in institutional repositories at Hospital Universitario La Paz/IdiPAZ. Data access is restricted to the research team in compliance with EU Regulation 2016/679 (GDPR) and Spanish data protection law.

No publications or documents are linked to this record.

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Registry details

Key details

Study ID
NCT07260643
Lead sponsor
Hospital Universitario La Paz
Responsible party
Luis Asensio Gomez (Consultant, Hospital Universitario La Paz) — Principal investigator
First posted
Dec 3, 2025
Start date
Dec 1, 2025 (estimated)
Primary completion
Jun 30, 2026 (estimated)
Completion
Aug 31, 2026 (estimated)
Last update
Dec 9, 2025

Study contacts

Luis Asensio-Gomez, Consultant
Contact
lasensio@salud.madrid.org
0034 91727000

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is not yet recruiting, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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