An interventional study of Subcostal Transversus Abdominis Plane Block and Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy and Postoperative Pain, sponsored by Diskapi Yildirim Beyazit Education and Research Hospital. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-10-16.
Sponsored by Diskapi Yildirim Beyazit Education and Research Hospital · Not applicable, Interventional, and Treatment
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period. Inadequate postoperative analgesia may negatively affect patient comfort and recovery, increase opioid consumption, and contribute to opioid-related adverse effects. Therefore, effective multimodal analgesic strategies are of considerable importance in patients undergoing laparoscopic cholecystectomy.
Subcostal transversus abdominis plane (TAP) block is a regional anesthesia technique used to provide analgesia for upper abdominal surgery. However, its analgesic coverage may be insufficient in some patients because of the complex innervation of the upper abdominal wall. The recto-intercostal fascial plane block has been described as a fascial plane block targeting the anterior branches of the thoracoabdominal nerves and may provide additional analgesic benefit when combined with subcostal TAP block.
This study aims to compare the postoperative analgesic efficacy of bilateral subcostal TAP block alone with that of bilateral subcostal TAP block combined with recto-intercostal fascial plane block in patients undergoing elective laparoscopic cholecystectomy.
5,224 studies on the registry are indexed under Pain, Postoperative; 1,154 are open to participants now.
This study's planned enrollment of 90 is above the median of 75 across 4,457 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Diskapi Yildirim Beyazit Education and Research Hospital is the lead sponsor of 70 studies on the registry; 12 are open to participants now.
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Exclusion Criteria:
Following induction of general anesthesia and before surgical incision, participants will receive a bilateral ultrasound-guided subcostal transversus abdominis plane block using a total volume of 40 mL of 0.20% bupivacaine.
Procedure: Subcostal Transversus Abdominis Plane Block
Following induction of general anesthesia and before surgical incision, participants will receive a bilateral ultrasound-guided subcostal transversus abdominis plane block using a total volume of 40 mL of 0.20% bupivacaine together with a bilateral ultrasound-guided recto-intercostal fascial plane block using a total volume of 30 mL of 0.20% bupivacaine.
Procedure: Subcostal Transversus Abdominis Plane Block · Procedure: Recto-Intercostal Fascial Plane Block
Following induction of general anesthesia and before surgical incision, a bilateral ultrasound-guided subcostal transversus abdominis plane block will be performed using a total volume of 40 mL of 0.20% bupivacaine.
Following induction of general anesthesia and before surgical incision, a bilateral ultrasound-guided recto-intercostal fascial plane block will be performed using a total volume of 30 mL of 0.20% bupivacaine.
Pain Score
Pain will be assessed at rest using the visual analog scale on a scale from 0 (no pain) to 100 (worst pain). Pain assessment will be done at 6th hour after surgery.
Time frame: At 6 hours after surgery.
Pain Scores
Pain will be assessed at rest using the visual analog scale on a scale from 0 (no pain) to 100 (worst pain). Pain assessment will be done at 0st, 1st, 2nd, 12th, and 24th hours after surgery.
Time frame: At 0, 1, 2, 12, and 24 hours after surgery.
Total Postoperative Opioid Consumption During the First 24 Hours After Surgery
Total Postoperative Opioid Consumption During the First 24 Hours After Surgery
Time frame: During the first 24 hours after surgery.
Start is estimated for Oct 2026; primary completion for Oct 2027, 12 months later.
Of 1,888 non-industry interventional studies with no phase under Pain, Postoperative, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 23. This study's planned 12 months is close to that.
Counting every sponsor, half of 1,901 studies reached it within 11 months; a quarter within 6 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Diskapi Yildirim Beyazit Education and Research Hospital