An interventional study of supportive psychotherapy plus QURAN recitation9Surah Ar -Rahman in Psychological Distress (Depression, Anxiety and Stress) Cancer, sponsored by Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST) University. Not yet recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-09-22.
Sponsored by Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST) University · Not applicable, Interventional, and Supportive care
Among 81 studies in Depression with a site in Pakistan — 23 open to participants now, 29 under way, none of them phase 3. Depression · Pakistan.
Among the 81 studies in Depression with a site in Pakistan, this one is the 55th largest by planned enrollment of the 76 interventional ones that give a count, is one of 11 that started in 2026, is one of 74 with no phase, reaches primary completion later than 26 of the 28 other live ones, and was the 81st registered.
8,582 studies on the registry are indexed under Depression; 1,723 are open to participants now.
Browse Depression studies →23 of the 81 studies in Depression with a site in Pakistan are open now. Recruiting first, the newest first:
Pakistan Institute of Living and Learning · Sites in Pakistan
Healthy volunteers
Khyber Medical University Peshawar · Sites in Pakistan
Ages 18+
Riphah International University · Sites in Pakistan
Healthy volunteers
Manahil Gill · Sites in Pakistan
Ages 18–55
Fazaia Ruth Pfau Medical College · Sites in Pakistan
Ages 18–45
A study can be open while its sites in Pakistan have not opened yet or have stopped. Only those recruiting at a site in Pakistan →
Of the 1,089 Depression studies recruiting now, 470 (43%) set no upper age limit and 519 (48%) stop at 75 or younger; 203 take children under 18; 311 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · no healthy volunteers.
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81 studies; the count open now beside each. This study's row is marked.
First in 2009; this study’s year is marked. 11 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 60 is below the median of 81 across 7,066 interventional studies indexed under Depression.
Median enrollment 101 across the 76 interventional studies, 390 across the 5 observational. Of the 47 that completed or were terminated, 4 (9%) have results posted.
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None of the 81 has an industry lead sponsor. The 10 most frequent:
This is the only study on the registry with Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST) University as lead sponsor.
Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST) University has 1 study filed under Depression — fewer than ten, so there is no comparison to draw.
5 of the studies in Depression with a site in Pakistan that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07819448Manahil GillAerobic Exercise as an Adjunct Therapy for Depression | 2027-02-01 |
| NCT07722949Khyber Medical University PeshawarFeasibility of a Culturally Adapted Nurse-Led COPE Intervention for Caregivers of Children With Autism Spectrum Disorder | 2027-03-30 |
| NCT07654179Riphah International UniversityMetformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation | 2027-06-11 |
| NCT07790835Pakistan Institute of Living and LearningCultural Adaptation of an Online Parenting Intervention to Reduce the Risk of Depression and Anxiety in Adolescents | 2027-09-30 |
| NCT07833982Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST) UniversityEfficacy of an Integrated Psychological Interventions Combined With Ar_Rahman Listening for Reducing Psychological Distress and Enhancing Hope and Quality of Life Among Cancer Patients: A Randomized Controlled Trial | 2027-11-30 |
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Among the 81 studies in Depression with a site in Pakistan, from their registry updates:
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This is a randomized control trial(RCT ID:25142101) to evaluate the efficacy of psychological intervention combined with listening to surah Ar- RAhman for reducing psychological distress and improving cancer patients' hope and overall QOL compare to standard care. participants will be randomly assigned to two groups: intervention group will receive 14-sessions based manualized psychotherapy plus daily listening to surah Ar- rehman for 12 weeks, and control group will receive standard care .psychological distress will be measured with DASS-21, Quality of Life (QLQ-C30) for assessing Quality of life and Adult hope scale for assessing hope before and after the intervention.
this is a two- arm parallel randomized control trial. Background: psychological distress is common in cancer patients and affects treatment outcomes. spiritual and religious interventions, particularly, listening to QURAN recitation(Surah Ar Rahman), have shown potential to reduce anxiety and depression giving hope anf improving overall QOL.
objective: To determine the effectiveness of psychological intervention combined with Surah Ar Rahman listening in reducing psychological distress and enhancing hope and Quality of Life in cancer patients Methods: approximately 60 adults cancer patients will be recruited and randomized(1:1) into intervention and control groups. intervention group: 8 weekly psychological counseling session (30-45 min) based on supportive psychotherapy and CBT techniques plus listening to surah Ar Rahman recitation by Qari Abdul Basit (20 min daily). control group : Standard medical care and general information. assessment at pre and post intervention .
Inclusion Criteria:
Inclusion Criteria
Exclusion Criteria:
Severe psychiatric disorders
participants will receive 12 week of psychological intervention weekly(30-45 min) counseling based supportive therapy plus daily listening to surh Ar Rahman recitation (Qari abdul basit, 20 min) via audio player.
Behavioral: supportive psychotherapy plus QURAN recitation9Surah Ar -Rahman
participants will receive standard oncological care and general health information without psychological intervention or QURAN recitation
participants in experimental group will receive 12 week psychological intervention : weekly 30-45 min counseling based on supportive therapy plus daily listening to Surah Ar Rahman recitation ( Qari Abdul Basit , 20 min ) via audio player, participants will be provided audio and intructed to listen daily and maintain a log.
psychological distress (DASS-21)
Psychological distress will be measured using DASS-21, a 21 item self-report instrument with 3 subscales: Depression (7 items) Anxiety(7 items) and stress(7 items). each item is scored on 0-3 Likert scale. total score range is 0-63, Scores of each subscale are categorized into five severity ranges: Normal, mild, moderate, severe and extremely severe. For depression normal range(0-9), mild(10-13), Moderate(14-20), Severe(21-27), Extremely severe(28+), for anxiety normal range(0-7), mild(8-9), Moderate(10-14), Severe(15-19), Extremely severe(20+),for stress normal range(0-14), mild(15-18), Moderate(19-25), Severe(26-33), Extremely severe(34+) While the scores do not provide a functional diagnosis, they indicate the potential presence of depression, anxiety, and stress
Time frame: baseline and 12 weeks post intervention
Quality of Life -EORTC QLQ-C30
Quality of life will be measured using European Organization for Research and treatment of Cancer Quality of life Questionnaire(EORTC-QLQ-C30) Version 3.0. it is 30-item questionnaire composed of 5 functional scales, 3 symptoms scales, a global health status scale and 6 single items. scores are transformed to 0-100 scale. higher score in functioning and global QoL indicates better QOL, higher score in symptoms indicates worse symptoms
Time frame: Baseline and 12 week post-intervention
Adult Hope scale(AHS)
hope will be measured using Adult hope scale(Snyder et al.,1991). it is 12-items scale with 4 agency items , 4 pathways items, and 4 distractors. items are scored on an 8-point Likert scale from 1- definitely False to 8= definitely true. total score range is 8-64. excluding distractors. higher score indicates higher level of hope
Time frame: baseline and 12 weeks post intervention
Plan to share: No — individual participants data(IPD) will not be shared due to ethical restrictions and to protect patient confidentiality as per institutional review board(IRB) policy. the study involved sensitive psychological data of cancer patients. De-identified summary data maybe available from principal investigator upon reasonable request after publication.
No publications or documents are linked to this record.
Start is estimated for Sep 2026; primary completion for Nov 2027, 14 months later.
Of 3,471 non-industry interventional studies with no phase under Depression, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's planned 14 months is below that.
Counting every sponsor, half of 3,569 studies reached it within 21 months; a quarter within 9 and three quarters within 41.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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