An interventional study of Topography Guided Repair and Tubularized Incised Plate Repair in Distal Hypospadias Repair, sponsored by Alexandria University. Completed at 1 site in Egypt. Open to male participants aged 6 Months to 16 Years. Per ClinicalTrials.gov, last updated 2026-09-30.
Sponsored by Alexandria University · Not applicable, Interventional, and Treatment
Among 36 studies in Hypospadias with a site in Egypt — 12 open to participants now, 13 under way, none of them phase 3. Hypospadias · Egypt.
Among the 36 studies in Hypospadias with a site in Egypt, this one is the 8th largest by enrollment of the 33 interventional ones that give a count, is one of 7 that started in 2023, is one of 29 with no phase, and was the 36th registered.
123 studies on the registry are indexed under Hypospadias; 34 are open to participants now.
Browse Hypospadias studies →12 of the 36 studies in Hypospadias with a site in Egypt are open now. Recruiting first, the newest first:
Tanta University · Sites in Egypt
Tanta University · Sites in Egypt
Tanta University · Sites in Egypt
Sohag University · Sites in Egypt
Sohag University · Sites in Egypt
A study can be open while its sites in Egypt have not opened yet or have stopped. Only those recruiting at a site in Egypt →
Of the 20 Hypospadias studies recruiting now, 4 (20%) set no upper age limit and 16 (80%) stop at 75 or younger; 18 take children under 18; 3 take healthy volunteers.
This study: 6 Months to 16 Years · male · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
36 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 1 · Phase 2 2 · Phase 3 1 · Phase 4 1
First in 2017; this study’s year is marked. 7 started in 2023.
This study's enrollment of 101 is above the median of 70 across 97 interventional studies indexed under Hypospadias.
Median enrollment 69 across the 33 interventional studies, 50 across the 3 observational. Of the 19 that completed or were terminated, 0 (0%) have results posted.
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None of the 36 has an industry lead sponsor. The 10 most frequent:
Alexandria University is the lead sponsor of 604 studies on the registry; 140 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Alexandria University has 1 study filed under Hypospadias — fewer than ten, so there is no comparison to draw.
2 of the studies in Hypospadias with a site in Egypt that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07676916Tanta UniversityMicrosurgical Single Versus Double Dartos Flap in Distal Hypospadias Repair | 2027-04-01 |
| NCT07757828Ain Shams UniversityEfficacy of PRF in Hypospadias Repair | 2027-08-01 |
Among the 36 studies in Hypospadias with a site in Egypt, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
This study compares two surgical techniques used to repair distal hypospadias in children: topography-guided repair (TGR), a newer approach, and tubularized incised plate (TIP) repair, a commonly used standard technique. Children with distal hypospadias were randomly assigned to receive one of the two procedures. Researchers assessed early surgical complications, need for additional surgery, and postoperative appearance and function during follow-up visits over 12 months. The study aims to determine whether TGR can be safely adopted by surgical teams other than its developer and to guide larger future studies.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Distal Hypospadias Repair using the topographic anatomical repair technique
Procedure: Topography Guided Repair
Distal Hypospadias Repair using the TiP technique
Procedure: Tubularized Incised Plate Repair
Topography-guided repair is a surgical procedure for primary distal penile hypospadias. The repair involves identification and mobilization of the spongiosal pillars, excision of the ventral hypoplastic urothelial sheet, approximation of the spongiosal tissue over a silicone catheter, and subcuticular closure of the glanular wings. An 8-Fr silicone catheter is maintained for 7 days after surgery.
Tubularized incised plate repair is a surgical procedure for primary distal penile hypospadias. The urethral plate is incised in the midline and tubularized to create a neourethra, followed by glans closure using 6-0 polyglactin sutures. An 8-Fr silicone catheter is maintained for 7 days after surgery. Postoperative dressing and wound-care protocols are the same as in the topography-guided repair group.
Complication-Free Rate
The proportion of participants without postoperative complications, including urethrocutaneous fistula, meatal stenosis, glanular dehiscence, or other complications, at 3 months after the primary repair. Participants were classified according to their current complication status before any revision surgery.
Time frame: 3 months after primary hypospadias repair
Complication-Free Rate at 12 Months
The proportion of participants without unresolved postoperative complications at 12 months after primary repair. Participants who had a complication that was successfully revised were classified as complication-free; participants with unresolved complications or pending revision were classified as complicated.
Time frame: 12 months after primary hypospadias repair
Hypospadias Objective Scoring Evaluation (HOSE) Score
HOSE is an examiner-scored assessment of postoperative hypospadias repair outcome. Scores range from 5 to 16, with scores of 14 or higher considered an acceptable outcome.
Time frame: 3 and 12 months after primary hypospadias repair
Plan to share: Yes — De-identified individual participant data underlying the published results, including baseline characteristics, intraoperative measurements, complications, revision status, and outcome scores, may be shared.
No publications or documents are linked to this record.
Ran from Dec 2023 to primary completion in Sep 2025, 20 months.
Of 60 non-industry interventional studies with no phase under Hypospadias, half reached primary completion within 15 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 39. This study's 20 months is above that.
Counting every sponsor, half of 60 studies reached it within 15 months; a quarter within 8 and three quarters within 39.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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