An interventional study of Mouth wash in Dental Caries, Streptococcal Infections and Mouthwashes, sponsored by British University In Egypt. Active, not recruiting at 1 site in Egypt. Open to participants aged 7 Years to 12 Years. Per ClinicalTrials.gov, last updated 2026-09-18.
Sponsored by British University In Egypt · Not applicable, Interventional, and Prevention
Among 205 studies in Dental Caries with a site in Egypt — 47 open to participants now, 67 under way, 1 of them phase 3. Dental Caries · Egypt.
Among the 205 studies in Dental Caries with a site in Egypt, this one is the 70th largest by planned enrollment of the 179 interventional ones, is one of 32 that started in 2025, is one of 153 with no phase, reaches primary completion later than 53 of the 66 other live ones, and was the 201st registered.
1,171 studies on the registry are indexed under Dental Caries; 209 are open to participants now.
This study's planned enrollment of 54 is close to the median of 60 across 967 interventional studies indexed under Dental Caries.
Browse Dental Caries studies →47 of the 205 studies in Dental Caries with a site in Egypt are open now, in 1 country. Each count lists the studies.
Of the 86 Dental Caries studies recruiting now, 18 (21%) set no upper age limit and 66 (77%) stop at 75 or younger; 60 take children under 18; 53 take healthy volunteers.
This study: 7 Years to 12 Years · all sexes · no healthy volunteers.
The full table on the hub →205 studies; the count open now beside each. This study's row is marked.
First in 2011; this study’s year is marked. 32 started in 2025.
Median enrollment 44 across the 179 interventional studies, 219 across the 26 observational. Of the 103 that completed or were terminated, 2 (2%) have results posted.
2 of 205 have an industry lead sponsor. The 10 most frequent:
British University In Egypt is the lead sponsor of 70 studies on the registry; 22 are open to participants now.
British University In Egypt has 2 studies filed under Dental Caries — fewer than ten, so there is no comparison to draw.
19 of the studies in Dental Caries with a site in Egypt that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07786805Tanta UniversityBite Force Recovery Following Pediatric Full Crown Restorations | 2026-11 |
| NCT07003360Mansoura UniversityClinical Evaluation of Bioactive Restorative Materials | 2026-11-02 |
| NCT05943782Ain Shams UniversityEvaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques. | 2026-12-01 |
| NCT07612540Cairo UniversityRetention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial | 2026-12-01 |
| NCT07262086Suez Canal UniversityClinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite | 2026-12-02 |
Among the 205 studies in Dental Caries with a site in Egypt, from their registry updates:
A randomized controlled trial that compares the antibacterial effectiveness of three mouthwashes-licorice, clove, and chlorhexidine-in Egyptian children aged 7-12 years.
The main focus is Streptococcus mutans, one of the main bacteria associated with dental caries. The saliva samples will be collected from the children and the amount of S. mutans will be measured before and after using the assigned mouthwash.
The children will be randomly divided into groups, with each group receiving one of the three mouthwashes. The bacterial counts will then be compared to determine which mouthwash is most effective at reducing salivary S. mutans.
The research question is whether natural mouthwashes made from licorice or clove reduce the bacteria that cause cavities as effectively as chlorhexidine in children?
The study could help determine whether licorice and clove are effective natural alternatives or adjuncts to chlorhexidine, particularly considering that chlorhexidine can have undesirable effects with prolonged use.
Overall aim: Compare and evaluate the antibacterial efficacy of the three mouthwashes
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Other: Mouth wash
Other: Mouth wash
Other: Mouth wash
The interventions will consist of three different mouthwashes: licorice mouthwash, clove mouthwash, and 0.2% chlorhexidine mouthwash. Each participant will use the mouthwash assigned to their study group according to the standardized study protocol. The herbal mouthwashes will be prepared using standardized licorice and clove extracts at predetermined concentrations, while the chlorhexidine group will receive 0.2% chlorhexidine mouthwash as the positive control. All mouthwashes will be provided in identical, appropriately labeled containers to maintain blinding where applicable. The interventions will be distinguished by their active ingredient and concentration, while the method, frequency, duration of use, and volume administered will be standardized across all groups.
Reduction of dental caries incidence in high-caries index pediatric patients using International Caries Detection and Assessment System.
Time frame: Baseline(Day 1), 2 weeks postoperative, then 3 months postoperative.
The reduction in Streptococcus mutans count following the use of licorice and clove mouthwashes in Egyptian pediatric patients aged from 7 to 12.
Time frame: Baseline(Day 1), 2 weeks postoperative, then 3 months postoperative.
Patient reported satisfaction, regarding the taste using a questionnaire.
Time frame: Through study completion, an average of 3 months.
Adverse events related to the use of the licorice and clove mouthwashes, regarding oral irritation and allergies using a questionnaire.
Time frame: Through study completion, an average of 3 months.
Plan to share: Undecided
No publications or documents are linked to this record.
Started Oct 2025 (actual). Primary completion is estimated for Jan 2027, 15 months after the start.
Of 469 non-industry interventional studies with no phase under Dental Caries, half reached primary completion within 15 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 30. This study's planned 15 months is close to that.
Counting every sponsor, half of 502 studies reached it within 15 months; a quarter within 7 and three quarters within 29.
How these figures are worked out, and which studies are left out of them.
This study is active, not recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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British University In Egypt