Streptococcal Infections clinical trials
The registry lists 146 studies for Streptococcal Infections across more than 10 countries. 14 are recruiting or about to start. 116 of them are mainly about Streptococcal Infections (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 5 narrower conditions too, such as Pneumococcal Infections: 585 studies, 86 open.
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Who runs them
GlaxoSmithKline (64) · Minervax ApS (7) · St George's, University of London (6) · CanSino Biologics Inc. (4) · Basilea Pharmaceutica (4) · Assiut University (2) · University Hospital, Strasbourg, France (2) · Ellume Pty Ltd (2)
What is being tested here
Drugs under test in Streptococcal Infections studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5, phase 3 first
- Feb 2027A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks) · Phase 3 · CanSino Biologics Inc.
- Jan 2027Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children. · British University In Egypt
- Jan 2027A Multicenter Evaluation of SalivIQ™ Strep A for Detecting Group A Streptococcus From Saliva and Throat Swabs in Patients With Acute Pharyngitis · SalivIQ Diagnostics, Inc.
- Mar 2027Factors Associated With Mortality in Streptococcal Anginosus Bacteremia · University Hospital, Strasbourg, France
- Jun 2027A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component Strep A Vaccine With Aluminum Hydroxide (Alum) or AS37 in Healthy Young Adults · GlaxoSmithKline
Who these studies take
Of the 10 Streptococcal Infections studies recruiting now, 6 (60%) set no upper age limit and 3 (30%) stop at 75 or younger. 4 (40%) take children under 18. 1 (10%) are for women only and 0 (0%) for men only; 2 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (30%) | 2 (20%) |
| 18 | 9 (90%) | 8 (80%) |
| 30 | 8 (80%) | 7 (70%) |
| 40 | 8 (80%) | 7 (70%) |
| 50 | 7 (70%) | 6 (60%) |
| 65 | 7 (70%) | 6 (60%) |
| 75 | 7 (70%) | 6 (60%) |
| 85 | 6 (60%) | 5 (50%) |
Across all 146 studies, recruiting or not: 72% stop at 75 or younger and 71% at 65; 64% take children; 21% are for women only and 1% for men only; 67% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Streptococcal Infections studies take
Of 29 phase 3 interventional studies under Streptococcal Infections, half reached primary completion within 10 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 13 mo9–25 · 12 studies | — | — |
| Phase 3 | 10 mo8–16 · 29 studies | 9 mo7–13 · 28 studies | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Stopped1
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 146. Browse all 146 → or search them.
- A Pivotal Safety and Immunogenicity GBS-NN/NN2 Vaccine Maternal Immunisation TrialNot yet recruitingNCT07922226Phase 2/3
- A Multicenter Evaluation of SalivIQ™ Strep A for Detecting Group A Streptococcus From Saliva and Throat Swabs in Patients With Acute PharyngitisRecruitingNCT078917281 country
- Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal SepticemiaRecruitingNCT07240077Phase 41 country
- A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component Strep A Vaccine With Aluminum Hydroxide (Alum) or AS37 in Healthy Young AdultsRecruitingNCT07085702Phase 11 country
- A Clinical Trial of the 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/Tetanus Toxoid)Not yet recruitingNCT07648641
- A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-A1 in Healthy Young AdultsRecruitingNCT07616934Phase 11 country
- mulTiplex Immunoassay qualiTy assuRance PanelRecruitingNCT075620611 country
- Factors Associated With Mortality in Streptococcal Anginosus BacteremiaRecruitingNCT073431671 country
- Clindamycin as Antimicrobial Treatment for Streptococcus Spp. PeRiprosthetic InfectionRecruitingNCT073356271 country
- Comprehensive Outcomes Monitoring for Peri- and Postnatal Invasive Group B Strep Sequelae (COMPPASS) RegistryNot yet recruitingNCT06896526
- Group B Streptococcus Infection and PROM IncidinceNot yet recruitingNCT06735703
- Development of a Serocorrelate of Protection Against Invasive Group B Streptococcus DiseaseRecruitingNCT047354191 country
- Serocorrelate of Protection Against GBS (PREPARE WP3)RecruitingNCT047320266 countries
- Invasive Group B Streptococcus Disease Burden and Its Antimicrobial Resistance in Malaysia Among Non-pregnant Adults.RecruitingNCT057260061 country
- CandyCollect Strep Throat TestingSuspendedNCT05175196Not applicable1 country
- GBS-NN/NN2 (50 µg of Each Fusion Protein [GBS-NN and GBS-NN2] in Combination With 500 µg Aluminum as Alhydrogel®) Given With and Without the Tdap Vaccine in Healthy Non-pregnant Women 18 to 49 Years of AgeWithdrawnNCT06494475Phase 2/3
- A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy InfantsCompletedNCT05412030Phase 22 countries
- Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children.Active, not recruitingNCT07828171Not applicable1 country
- A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant WomenActive, not recruitingNCT06592586Phase 2/32 countries
- A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks)Active, not recruitingNCT07017777Phase 31 country
- Study of a Group B Streptococcus Vaccine in Pregnant Women Living With HIV and in Pregnant Women Who do Not Have HIVCompletedNCT04596878Phase 22 countries
- Group A Streptococcus Saliva StudyActive, not recruitingNCT06473506Not applicable1 country
- Systematic Search for Primary Immunodeficiency in Adults With InfectionsCompletedNCT02972281Not applicable1 country
- A Strep Throat Controlled Human Infection Trial in Healthy AdultsCompletedNCT06992141Early Phase 11 country
- Phase I/II Study to a Assess the GBS-06 Vaccine Manufactured by Inventprise, Inc., in Healthy, Non-Pregnant, Adult Women of Childbearing Age.Active, not recruitingNCT06611371Phase 1/22 countries
- Study to Evaluate the Safety, Tolerability and Immunogenicity of Three Doses of GBS Vaccine in Elderly ParticipantsCompletedNCT05782179Phase 11 country
- Immunogenicity and Safety of GBS-NN/NN2 in Pregnant WomenCompletedNCT05154578Phase 23 countries
- A Trial of a Peptide-based Group A Streptococcal (GAS) Vaccine Candidate in Healthy Individuals.CompletedNCT04882514Phase 1/21 country
- Group B Streptococcus Response After Probiotic ExposureCompletedNCT04721912Phase 31 country
- Serosurveillance Study of Maternally Derived Anti-GBS AntibodyActive, not recruitingNCT045492201 country
- Colonization with Group B Streptococcus During PregnancyCompletedNCT036714861 country
- Phase III Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and Above (PICTPCV13i)CompletedNCT04841369Phase 31 country
- Clinical Trial Investigating the Safety and Immunogenicity of GBS6 in Pregnant Women With and Without HIV (PREPARE)Active, not recruitingNCT05832502Phase 21 country
- Maternal, Neonatal and Infant Outcomes at Kawempe National Referral HospitalActive, not recruitingNCT046539481 country
- Clinical Performance of the Checkable Medical At-Home Strep A TestCompletedNCT051073621 country
- Streptococcus Pyogenes Carriage Acquisition and Transmission StudyCompletedNCT051175281 country
- Phase I Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and AboveCompletedNCT04100772Phase 11 country
- Antimicrobial Stewardship Program (ASP) in Patients With a Sore ThroatCompletedNCT03408704Not applicable1 country
- Pilot Study of Strepic® Device for the Diagnosis of Group A Streptococcal PharyngitisCompletedNCT037770981 country
- MATERNAL AND NEONATAL SCREENING FOR GROUP B STREPTOCOCCI : A Follow up STUDYWithdrawnNCT042277301 country
- Effect of a New Probiotic Strain in the Reduction of Group B Streptococcus Colonization in Pregnant WomenCompletedNCT03669094Not applicable1 country
- Time Frame for GBS ScreeningWithdrawnNCT04116645
- A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF A BOOSTER DOSE OF A GROUP B STREPTOCOCCUS 6 VALENT POLYSACCHARIDE CONJUGATE VACCINE (GBS6) IN HEALTHY ADULTSCompletedNCT04258995Phase 21 country
- Validation of the GenePOC GBS Assay for the Detection of the Cfb Gene From Streptococcus Agalactiae StrainsCompletedNCT02718157Not applicable2 countries
- Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in ChildrenWithdrawnNCT02899702Phase 41 country
- Primary Vaccination With Either Synflorix™ or Prevenar 13™ or Both Vaccines and Booster Vaccination With Synflorix™CompletedNCT01641133Phase 31 country
- Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' Pneumococcal Vaccine 2830930A Administered in ToddlersCompletedNCT01485406Phase 11 country
- Group B Streptococcus Vaccine in Healthy FemalesCompletedNCT03807245Phase 11 country
- Assessment of Antibody Persistence in Children Previously Vaccinated With Pneumococcal Conjugate VaccineCompletedNCT00624819Phase 31 country
- Evaluation of Effectiveness of GSK Biologicals' Pneumococcal Conjugate Vaccine 1024850A Against Invasive DiseaseCompletedNCT00861380Phase 31 country