An observational study in Post-induction Hypotension, sponsored by University Hospital Ostrava. Recruiting at 1 site in Czechia. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-25.
Sponsored by University Hospital Ostrava · Observational
This monocentre prospective trial aims to evaluate the relationship between fasting time and the occurence of PIH (post-induction hypotension).
A decrease in blood pressure (BP) after induction of general anesthesia (GA) is a common phenomenon. The etiology is multifactorial (vasodilatory and dále negative inotropic effects of anaesthetics, reduction in sympathetic tone, the effect of positive pressure ventilation and others). Relative hypovolemia due to patient fasting is one of the factors that can have a significant influence on the decrease in blood pressure after induction of GA. Different lengths of fasting may thus lead to variations in both the incidence of hypotension after induction of GA (post-induction hypotension - PIH) and the severity of the BP drop.
Patients undergoing surgery in general anaesthesia
Exclusion Criteria:
Post induction hypotension (PIH)
The incidence of the post induction hypotension (PIH) will be assessed in the study subjects.
Time frame: 1 month
Seriousness of post induction hypotension (PIH)
Seriousness of post induction hypotension (PIH) will be assessed to determine whether patients with longer fasting time experience a significant reduction of blood pressure after induction of general anaesthesia.
Time frame: 1 month
Comparison of other PIH risk factors
The risk factors such as comordibity, chronic medication, type and doses of induction drugs will be compared.
Time frame: 1 month
Plan to share: No — There is no plan to make individual participant data available to other researchers. The data may be provided upon request.
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University Hospital Ostrava