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CompletedNCT07785518Updated Aug 25, 2026

Prevalenza Della Insulino Resistenza e Correlate Malattie Cardiovascolari Nella città di Napoli

An observational study in Insulin Resistance Syndrome, Cardio Vascular Disease and Prevalence, sponsored by Comune di Napoli. Completed at 1 site in Italy. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-08-25.

Sponsored by Comune di Napoli · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
123,752
Ages
18 Years to 60 Years
Sex
All
01

Study summary

This is an observational retrospective study to verify the prevalence of insulin resistance (IR) in the municipality of Naples and ita association with cardiovascular diseases.

Primary outcome measure 1: The prevalence of IR. Primary outcome measure 2: The prevalence of cardiovascular diseases in subjects with IRnand in subjects without IR.

The data for analysis will be derived from the database of COMEGEN, a cooperative of general practitioners (ASL Napoli 1 Centro)who follow about 200,000 individuals of the ten districts of the municipality of Naples. As surrogate index of IR will be used the TyG with the cutoff ≥8.5. Aldo the prevalence of cardiovascular diseases in the two groups will be derivedby the registered cardiovascular diseases in the database.

02

Conditions studied

  • Insulin Resistance Syndrome
  • Cardio Vascular Disease
  • Prevalence

Keywords

  • Insulin Resistance
  • Cardiovascular disease
  • Hyperinsulinemia
  • Prevalence
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In context

Metabolic Syndrome

2,116 studies on the registry are indexed under Metabolic Syndrome; 347 are open to participants now.

This study's enrollment of 123,752 is above the median of 197 across 496 observational studies indexed under Metabolic Syndrome.

Browse Metabolic Syndrome studies →

Lead sponsor

This is the only study on the registry with Comune di Napoli as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

All the subjects registered in the database of COMEGEN aged between 18 and 60 without a diagnosis of diabetes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • all the subjects who have a registered value of glucose and triglycerides in the same day within the last 6 months

Exclusion criteria

Exclusion Criteria:

  • diagnosis of overt diabetes
05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
123,752 participants (actual)
Target follow-up
3 Months
Patient registry
Yes

Interventions

  • OtherNo Intervention: Observational Cohort

    There is no intervention

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What researchers measure

Primary outcomes

  1. Prevalence of insulin resistance

    Time frame: 30 days

07

Study locations

1 site
  • Comune di Napoli
    Naples, 80100, Italy
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References and documents

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 25, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07785518
Lead sponsor
Comune di Napoli
Responsible party
Sponsor
First posted
Aug 25, 2026
Start date
Jan 25, 2026
Primary completion
May 6, 2026
Completion
Jun 30, 2026
Last update
Aug 25, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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