An observational study in Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction and Donor Site Complication, sponsored by Gazi University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2026-10-09.
Sponsored by Gazi University · Observational
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Among 43 studies in Anterior Cruciate Ligament Injuries with a site in Turkey — 18 open to participants now, 19 under way, none of them phase 3. Anterior Cruciate Ligament Injuries · Turkey.
Among the 43 studies in Anterior Cruciate Ligament Injuries with a site in Turkey, this one is the 16th largest by planned enrollment of the 16 observational ones that give a count, is one of 9 that started in 2026, is one of 16 observational ones, reaches primary completion later than 16 of the 18 other live ones, and was the 41st registered.
625 studies on the registry are indexed under Anterior Cruciate Ligament Injuries; 192 are open to participants now.
Browse Anterior Cruciate Ligament Injuries studies →18 of the 43 studies in Anterior Cruciate Ligament Injuries with a site in Turkey are open now. Recruiting first, the newest first:
Gazi University · Sites in Turkey
Ages 18–40 · Healthy volunteers
Sakarya University · Sites in Turkey
Ages 18–50
Acibadem University · Sites in Turkey
Ages 18–50
Uskudar University · Sites in Turkey
Ages 20–40 · Healthy volunteers
Ankara University · Sites in Turkey
Ages 18–65
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 122 Anterior Cruciate Ligament Injuries studies recruiting now, 27 (22%) set no upper age limit and 92 (75%) stop at 75 or younger; 46 take children under 18; 21 take healthy volunteers.
This study: 18 Years to 55 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
43 studies; the count open now beside each. This study's row is marked.
First in 2018; this study’s year is marked. 9 started in 2026.
This study's planned enrollment of 20 is below the median of 98 across 153 observational studies indexed under Anterior Cruciate Ligament Injuries.
Median enrollment 40 across the 27 interventional studies, 61 across the 16 observational. Of the 22 that completed or were terminated, 0 (0%) have results posted.
This tab as a report to print or save as PDF → With an account.
None of the 43 has an industry lead sponsor. The 10 most frequent:
Gazi University is the lead sponsor of 551 studies on the registry; 102 are open to participants now.
Gazi University has 2 studies filed under Anterior Cruciate Ligament Injuries — fewer than ten, so there is no comparison to draw.
8 of the studies in Anterior Cruciate Ligament Injuries with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07831941Umraniye Education and Research HospitalEffect of Tourniquet Use on the Pivot Shift Test | 2026-11-30 |
| NCT07876635Sakarya UniversityEvaluation of the Correlation Between Bone Tunnel Projection Placement and Clinical Outcomes in Anterior Cruciate Ligament Reconstruction Surgery | 2027-01-02 |
| NCT06571227Kırklareli UniversityEstablishing the Clinical Significance Values of the Lysholm Knee Score | 2027-04 |
| NCT06571240Kırklareli UniversityValidity and Reliability of the Turkish Version of the Tegner Activity Score | 2027-04 |
| NCT07671729Acibadem UniversityQuadriceps Tendon vs Peroneus Longus Tendon in ACL Reconstruction | 2027-05 |
Add all 8 to your calendar (.ics) → With an account.
Among the 43 studies in Anterior Cruciate Ligament Injuries with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This prospective longitudinal observational cohort study will characterize recovery of donor-ankle sensorimotor function in adults who have undergone primary anterior cruciate ligament reconstruction using a peroneus longus tendon autograft. Twenty participants aged 18 to 55 years will be evaluated at postoperative 6-8 weeks, 3 months, and 6 months. The donor limb and the contralateral non-donor limb will be compared using surface electromyography of the peroneus longus, force-platform measures of postural control, inertial-sensor gait analysis, active ankle joint-position sense testing, and clinical and patient-reported foot and ankle function measures. The study does not assign the surgical procedure or rehabilitation treatment.
Peroneus longus tendon autograft is used as an alternative graft source for anterior cruciate ligament reconstruction, but the longitudinal course of donor-site sensorimotor recovery has not been sufficiently described with objective measures. This study is designed to examine within-participant changes over time and differences between the donor and contralateral non-donor limbs.
Eligible participants who underwent primary unilateral anterior cruciate ligament reconstruction with a peroneus longus tendon autograft at Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital or Halil Şıvgın Çubuk State Hospital and who are referred to the Sports Health Unit of Gazi University will be followed at postoperative 6-8 weeks, 3 months, and 6 months. No graft type, surgery, or rehabilitation intervention is assigned by the investigators.
At each assessment, peroneus longus activation will be recorded during single-leg heel-rise and medially inclined heel-rise tasks using surface electromyography and normalized to a session-specific maximal voluntary isometric contraction. Postural control will be assessed with KFORCE Plates during double-leg and single-leg balance tasks. Spatiotemporal gait and pelvic kinematics will be recorded with the G-Walk inertial sensor system. Active ankle joint-position sense will be assessed on a Cybex NORM dynamometer using a 15-degree eversion target. Foot and ankle function will be assessed using the Foot and Ankle Ability Measure.
The primary analysis will examine time, limb, and time-by-limb effects across the three postoperative assessments. Parametric data will be analyzed using two-way repeated-measures analysis of variance, with nonparametric alternatives used when assumptions are not met. The planned enrollment is 20 participants, allowing for approximately 20% attrition from the minimum required sample of 16 completers.
Adults aged 18 to 55 years who have undergone primary unilateral anterior cruciate ligament reconstruction using a peroneus longus tendon autograft as part of routine clinical care and are referred to the Sports Health Unit, Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, for postoperative rehabilitation and functional assessment. Eligible participants will be enrolled consecutively during the study period.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Adults after primary unilateral ACL reconstruction using a peroneus longus tendon autograft. Participants will undergo observational assessments at postoperative 6-8 weeks, 3 months, and 6 months. Donor-limb measures will be compared with measurements from the contralateral non-donor limb. No intervention is assigned by the study.
Procedure: Anterior Cruciate Ligament Reconstruction Using a Peroneus Longus Tendon Autograft
Participants undergo primary anterior cruciate ligament reconstruction using a peroneus longus tendon autograft as part of their routine clinical care. The graft choice and surgical procedure are determined by the treating orthopedic surgeon independently of study participation. The study does not assign or modify the graft choice, surgical technique, or postoperative rehabilitation. Participants receive routine postoperative rehabilitation according to their clinical needs, while donor-ankle sensorimotor recovery is assessed prospectively at 6-8 weeks, 3 months, and 6 months after surgery.
Change in Mean Center of Pressure Velocity During Single-Leg Balance
Mean center of pressure (CoP) velocity during a 10-second single-leg stance, assessed separately with eyes open and eyes closed on KFORCE Plates. Each limb will be tested in three trials, and the mean for each condition will be used. Values are expressed in millimeters per second (mm/s); lower values indicate less postural sway. Change from the postoperative 6-8-week assessment to 3 and 6 months and donor-versus-contralateral limb differences will be evaluated.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in CoP Path Length During Single-Leg Balance
Total CoP path length during a 10-second single-leg stance with eyes open and eyes closed on KFORCE Plates, averaged across three valid trials for each limb and condition. Unit: millimeters (mm); lower values indicate less sway.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in CoP Ellipse Area During Single-Leg Balance
Ellipse area of CoP excursion during a 10-second single-leg stance with eyes open and eyes closed on KFORCE Plates, averaged across three valid trials. Unit: square millimeters (mm²); lower values indicate less sway area.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Mean CoP Velocity During Double-Leg Balance
Mean CoP velocity during 30-second double-leg quiet stance with eyes open and eyes closed on KFORCE Plates, averaged across three trials per condition. Unit: millimeters per second (mm/s).
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in CoP Path Length During Double-Leg Balance
Total CoP path length during 30-second double-leg quiet stance with eyes open and eyes closed on KFORCE Plates, averaged across three trials per condition. Unit: millimeters (mm).
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in CoP Ellipse Area During Double-Leg Balance
Ellipse area of CoP excursion during 30-second double-leg quiet stance with eyes open and eyes closed on KFORCE Plates, averaged across three trials per condition. Unit: square millimeters (mm²).
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Mean Normalized Peroneus Longus RMS Amplitude During Single-Leg Heel Rise
Mean root-mean-square surface EMG amplitude of the peroneus longus during the concentric, isometric, and eccentric phases of a metronome-paced single-leg heel rise. Each phase is reported separately as a percentage of session-specific maximal voluntary isometric contraction (%MVIC), averaged across three repetitions for each limb.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Peak Normalized Peroneus Longus RMS Amplitude During Single-Leg Heel Rise
Peak root-mean-square surface EMG amplitude during the concentric, isometric, and eccentric phases of a single-leg heel rise. Each phase is reported separately as %MVIC and averaged across three repetitions for each limb.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Mean Normalized Peroneus Longus RMS Amplitude During Incline Heel Rise
Mean root-mean-square surface EMG amplitude during the concentric, isometric, and eccentric phases of a single-leg heel rise on a rigid platform with approximately 30 degrees of medial inclination. Each phase is reported separately as %MVIC and averaged across three repetitions for each limb.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Peak Normalized Peroneus Longus RMS Amplitude During Incline Heel Rise
Peak root-mean-square surface EMG amplitude during the concentric, isometric, and eccentric phases of the medially inclined single-leg heel-rise task. Each phase is reported separately as %MVIC and averaged across three repetitions for each limb.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Ankle Joint Position Sense Absolute Error
Absolute difference between the 15-degree eversion target and the angle reproduced by the participant during active joint-position sense testing with eyes closed on a Cybex NORM dynamometer. Each limb will be evaluated separately. Unit: degrees (°); lower values indicate greater position-sense accuracy.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Self-Selected Gait Speed
Walking speed recorded with the G-Walk inertial sensor during self-selected walking over an approximately 10-meter walkway. The middle portion of the walk will be analyzed and three trials will be averaged. Unit: meters per second (m/s).
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Gait Cadence
Cadence recorded with the G-Walk inertial sensor during self-selected walking, averaged across three trials. Unit: steps per minute.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Step Length
Step length recorded with the G-Walk inertial sensor during self-selected walking, averaged across three trials. Unit: meters (m).
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Gait Symmetry Index
Between-limb gait symmetry index derived from G-Walk spatiotemporal data. Unit: percent (%); values closer to the device-defined symmetry reference indicate greater symmetry.
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Pelvic Tilt During Gait
Sagittal-plane pelvic tilt measured by the G-Walk inertial sensor during self-selected walking, averaged across three trials. Unit: degrees (°).
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in Pelvic Obliquity During Gait
Frontal-plane pelvic obliquity measured by the G-Walk inertial sensor during self-selected walking, averaged across three trials. Unit: degrees (°).
Time frame: Postoperative 6-8 weeks, 3 months, and 6 months
Change in FAAM Activities of Daily Living Subscale
Foot and Ankle Ability Measure Activities of Daily Living subscale, transformed to a 0%-100% score. Higher percentages indicate better self-reported function.
Time frame: Preoperative, Postoperative 6-8 weeks, 3 months, and 6 months
Change in FAAM Sports Subscale
Foot and Ankle Ability Measure Sports subscale, transformed to a 0%-100% score. Higher percentages indicate better self-reported sport-related function.
Time frame: Preoperative, Postoperative 6-8 weeks, 3 months, and 6 months
Plan to share: No — No individual participant data sharing plan has been specified for this study.
No publications or documents are linked to this record.
Started Aug 2026 (actual). Primary completion is estimated for Aug 2027, 11 months after the start.
Of 73 non-industry observational studies under Anterior Cruciate Ligament Injuries, half reached primary completion within 36 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 167. This study's planned 11 months is below that.
Counting every sponsor, half of 82 studies reached it within 37 months; a quarter within 13 and three quarters within 76.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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Anterior Cruciate Ligament Injuries →