ClinicalTrials.gg
CompletedNCT07761741Updated Oct 22, 2026

Title of the Research: Effect of Manual Lymphatic Drainage Massage Combined With Therapeutic Exercises On Lower Limbs Edema During Late Pregnancy

An interventional study of manual lymphatic drainage massage technique with specific therapeutic exercise in Pregnancy Complication, sponsored by Beni-Suef University. Completed at 2 sites in Egypt. Open to female participants aged 25 Years to 35 Years. Per ClinicalTrials.gov, last updated 2026-10-22.

Sponsored by Beni-Suef University · Not applicable, Interventional, and Treatment

Updated Oct 22, 2026Now CompletedFirst site in Egypt+7 moreGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
25 Years to 35 Years
Sex
Female
01

Study summary

Objective of the study is to investigate the effect of adding manual lymphatic drainage massage to classical therapeutic exercises on resolving physiological lower limbs edema in late pregnancy women. The main question to be answered by this study: Does adding manual lymphatic drainage massage to classical therapeutic exercises have effect on resolving physiological lower limbs edema in late pregnancy ? Researchers will compare 2 groups of 60 participants group A (study group) will include participants who will join a physiotherapy plan of care in the form of sessions compose of manual lymphatic drainage massage technique with specific therapeutic exercise as well as wearing compression garments and advice. While, group B will involve control participants who will follow routine care and advice as well as wearing the same compression garments as group A participants.

02

Conditions studied

  • Pregnancy Complication
03

In context

Pregnancy Complications

411 studies on the registry are indexed under Pregnancy Complications; 113 are open to participants now.

This study's enrollment of 60 is below the median of 144 across 205 interventional studies indexed under Pregnancy Complications.

Browse Pregnancy Complications studies →

Lead sponsor

Beni-Suef University is the lead sponsor of 349 studies on the registry; 125 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

The criteria were revised on the registry on Oct 22, 2026. See what changed

Ages eligible
25 Years to 35 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Pregnant women at 3rd trimester of pregnancy diagnosed with physiological lower limbs edema

Exclusion criteria

Exclusion Criteria:

  • pre-eclampsia
  • heart diseases
  • gestational diabetes mellitus
  • respiratory diseases causing excessive coughing or sneezing
  • chronic physical or mental illness
  • other pain conditions
  • coagulation disturbances
  • had any medical condition that would or failed to complete an form.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

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You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Care provider)
Enrollment
60 participants (actual)

Study arms

  • No intervention
    Control group
  • Experimental
    Intervention group

    Other: manual lymphatic drainage massage technique with specific therapeutic exercise

Interventions

  • Othermanual lymphatic drainage massage technique with specific therapeutic exercise

    Physiotherapy plan of care in the form of sessions compose of manual lymphatic drainage massage technique with specific therapeutic exercise as well as wearing compression garments and advice.

06

What researchers measure

Primary outcomes

  1. Ankle and foot circumference

    Time frame: 2 month

07

Study locations

2 sites
  • Faculty of Medicine- Beni-Suef University
    Banī Suwayf, Beni Suweif Governorate, Egypt
  • Beni-Suef University
    Banī Suwayf, Egypt
08

Updates

1 registry update since Sep 25, 2026
Status
Not yet recruiting→Completed
changed Oct 22, 2026
Sites
2 sites added — first site in Egypt
Show 2 added (2 Egypt)
  • Faculty of Medicine- Beni-Suef University · Banī Suwayf, Egypt
  • Beni-Suef University · Banī Suwayf, Egypt
Oct 22, 2026
Start date
Aug 8, 2026→Aug 9, 2026 (actual)
Oct 22, 2026
Primary completion
Oct 1, 2026→Oct 17, 2026 (actual)
Oct 22, 2026
Study completion
Oct 15, 2026→Oct 17, 2026 (actual)
Oct 22, 2026
Eligibility
1 inclusion criterion added, 1 removed; 8 exclusion criteria added, 1 removed
What changed in the criteria
Inclusion criteria
  • Removeda total of 60 women will be recruited from the Antenatal Clinic of Beni-Suef University Hospital, Beni-Suef, Egypt. Their ages will be ranged from 25-35 years and their body mass index (BMI) will be ranged from 30-35 kg/m2. All participants are pregnant women at 3rd trimester of pregnancy 28-32 weeks' of gestation diagnosed with late pregnancy physiological lower limbs edema
  • AddedPregnant women at 3rd trimester of pregnancy diagnosed with physiological lower limbs edema
Exclusion criteria
  • RemovedWomen will be excluded from the study, if they were diagnosed with any risk pregnancy conditions such as pre-eclampsia, heart diseases, gestational diabetes mellitus respiratory diseases causing excessive coughing or sneezing, chronic physical or mental illness, other pain conditions, coagulation disturbances, had any medical condition that would or failed to complete an informed consent form.
  • Addedpre-eclampsia
  • Addedheart diseases
  • Addedgestational diabetes mellitus
  • Addedrespiratory diseases causing excessive coughing or sneezing
  • Addedchronic physical or mental illness
  • Addedother pain conditions
  • Addedcoagulation disturbances
  • Addedhad any medical condition that would or failed to complete an informed consent form.
Oct 22, 2026
Interventions
Removed Control group. Arms added: Control group; arms removed: No Intervention
Oct 22, 2026
Show all 1 update
  1. Oct 22, 2026
    Not yet recruiting→Completed
    2 sites added — first site in Egypt
    Show 2 added (2 Egypt)
    • Faculty of Medicine- Beni-Suef University · Banī Suwayf, Egypt
    • Beni-Suef University · Banī Suwayf, Egypt
    Start date Aug 8, 2026→Aug 9, 2026 (now actual)
    Primary completion Oct 1, 2026→Oct 17, 2026 (now actual)
    Study completion Oct 15, 2026→Oct 17, 2026 (now actual)
    Eligibility 1 inclusion criterion added, 1 removed; 8 exclusion criteria added, 1 removed
    What changed in the criteria
    Inclusion criteria
    • Removeda total of 60 women will be recruited from the Antenatal Clinic of Beni-Suef University Hospital, Beni-Suef, Egypt. Their ages will be ranged from 25-35 years and their body mass index (BMI) will be ranged from 30-35 kg/m2. All participants are pregnant women at 3rd trimester of pregnancy 28-32 weeks' of gestation diagnosed with late pregnancy physiological lower limbs edema
    • AddedPregnant women at 3rd trimester of pregnancy diagnosed with physiological lower limbs edema
    Exclusion criteria
    • RemovedWomen will be excluded from the study, if they were diagnosed with any risk pregnancy conditions such as pre-eclampsia, heart diseases, gestational diabetes mellitus respiratory diseases causing excessive coughing or sneezing, chronic physical or mental illness, other pain conditions, coagulation disturbances, had any medical condition that would or failed to complete an informed consent form.
    • Addedpre-eclampsia
    • Addedheart diseases
    • Addedgestational diabetes mellitus
    • Addedrespiratory diseases causing excessive coughing or sneezing
    • Addedchronic physical or mental illness
    • Addedother pain conditions
    • Addedcoagulation disturbances
    • Addedhad any medical condition that would or failed to complete an informed consent form.
    Interventions Removed Control group. Arms added: Control group; arms removed: No Intervention
    + 2 other changes: index terms and verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

09

Registry details

Key details

Study ID
NCT07761741
Responsible party
Eman Awad (Associate professor of physical therapy for Woman's Health, Beni-Suef University) — Principal investigator
First posted
Aug 12, 2026
Start date
Aug 9, 2026
Primary completion
Oct 17, 2026
Completion
Oct 17, 2026
Last update
Oct 22, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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