An interventional study of Toothpaste in Teeth Staining, sponsored by Boka LLC. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-13.
Sponsored by Boka LLC · Not applicable, Interventional, and Other
Among 13 studies in Tooth Discoloration with a site in United States — 3 open to participants now, 3 under way, none of them phase 3. Tooth Discoloration · United States.
Among the 13 studies in Tooth Discoloration with a site in United States, this one is the 6th largest by enrollment, is one of 3 that started in 2026, is one of 12 with no phase, and was the 11th registered.
105 studies on the registry are indexed under Tooth Discoloration; 19 are open to participants now.
This study's enrollment of 100 is above the median of 48 across 97 interventional studies indexed under Tooth Discoloration.
Browse Tooth Discoloration studies →3 of the 13 studies in Tooth Discoloration with a site in United States are open now, in 1 country. Each count lists the studies.
Of the 8 Tooth Discoloration studies recruiting now, 1 (13%) set no upper age limit and 7 (88%) stop at 75 or younger; 2 take children under 18; 4 take healthy volunteers.
This study: 18 Years and older · all sexes · healthy volunteers too.
The full table on the hub →13 studies; the count open now beside each. This study's row is marked.
First in 2006; this study’s year is marked. 3 started in 2026.
Median enrollment 91 across the 13 interventional studies. Of the 10 that completed or were terminated, 1 (10%) have results posted.
10 of 13 have an industry lead sponsor. The 9 most frequent:
Boka LLC is the lead sponsor of 3 studies on the registry; none are open to participants now.
Boka LLC has 3 studies filed under Tooth Discoloration — fewer than ten, so there is no comparison to draw.
1 of the studies in Tooth Discoloration with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07836998HALEONA Study to Assess the Efficacy of an Experimental Mouthwash Used With a Marketed Whitening Toothpaste on Stain Build-up | 2026-12 |
Among the 13 studies in Tooth Discoloration with a site in United States, from their registry updates:
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains Over 4 Weeks of Unsupervised Use.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Toothpaste
Other: Toothpaste
Toothpaste with stain removing abilities
Tooth color
The Modified Lobene Stain Index (MLSI) Area x Intensity score for the overall tooth surfaces will be used for measurement of tooth color. The Primary Endpoint is the MLSI (extrinsic stain mean scores) at the 4-week time point compared to baseline.
Time frame: 4 weeks
ORAL SOFT TISSUE INTEGRITY
To determine the oral soft tissue (OST) tolerance of the dentifrices. To compare the change from baseline in stain levels as represented by the MLSI scores for overall, gingival, interproximal and body areas of the facial and lingual surfaces for each dentifrice after 4 weeks of product use.
Time frame: 4 WEEKS
Plan to share: No
No publications or documents are linked to this record.
Ran from May 2026 to primary completion in Jun 2026, 1 month.
Of 52 interventional studies with no phase under Tooth Discoloration, half reached primary completion within 8 months of starting (the median), counting those still running; a quarter within 2 and three quarters within 18. This study's 1 month is below that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Boka LLC