An interventional study of Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1) in Exercise, Fatigue and Sport Physiology, sponsored by Poznan University of Physical Education. Not yet recruiting at 1 site in Poland. Open to female participants aged 16 Years to 22 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-12.
Sponsored by Poznan University of Physical Education · Not applicable, Interventional, and Other
Among 18 studies in Fatigue with a site in Poland — 6 open to participants now, 6 under way, 1 of them phase 3. Fatigue · Poland.
Among the 18 studies in Fatigue with a site in Poland, this one is the 12th largest by planned enrollment of the 12 interventional ones, is one of 3 that started in 2026, is one of 7 with no phase, and was the 18th registered.
2,229 studies on the registry are indexed under Fatigue; 426 are open to participants now.
This study's planned enrollment of 25 is below the median of 54 across 1,757 interventional studies indexed under Fatigue.
Browse Fatigue studies →6 of the 18 studies in Fatigue with a site in Poland are open now, in 12 countries. Each count lists the studies.
Of the 240 Fatigue studies recruiting now, 112 (47%) set no upper age limit and 98 (41%) stop at 75 or younger; 24 take children under 18; 74 take healthy volunteers.
This study: 16 Years to 22 Years · female · healthy volunteers too.
The full table on the hub →18 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 3 started in 2026.
Median enrollment 94 across the 12 interventional studies, 29 across the 6 observational. Of the 12 that completed or were terminated, 3 (25%) have results posted.
6 of 18 have an industry lead sponsor. The 10 most frequent:
Poznan University of Physical Education is the lead sponsor of 90 studies on the registry; 27 are open to participants now.
Poznan University of Physical Education has 8 studies filed under Fatigue — fewer than ten, so there is no comparison to draw.
4 of the studies in Fatigue with a site in Poland that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07752459Poznan University of Physical EducationPhysiological Responses to Basketball-Specific Interval Exercise in Female Basketball Players | 2026-11-30 |
| NCT06371352Jakub AntczakEffect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression | 2026-12 |
| NCT06668649Jakub AntczakPolish Version Fatigue Severity Scale | 2026-12-31 |
| NCT06830655Medical University of GdanskFunctional and Performance Determinants in Climbers: Examining the Role of Mobility, Stability, and Fatigue Across Proficiency Levels | 2027-02 |
Among the 18 studies in Fatigue with a site in Poland, from their registry updates:
This study aims to evaluate the effects of interval exercise on metabolic and inflammatory responses, energy substrate utilization, and fatigue in trained female basketball players. High-intensity intermittent exercise is a key component of basketball performance and induces substantial metabolic and physiological stress. However, the acute relationships between exercise-induced metabolic changes, inflammatory responses, substrate utilization, and fatigue in female basketball players remain insufficiently understood.
In this prospective interventional study, eligible female basketball players will complete a standardized interval exercise protocol designed to replicate the physiological demands of competitive basketball. Physiological, biochemical, and perceptual measurements will be collected before exercise, immediately after exercise, and during recovery. Primary outcomes include changes in metabolic and inflammatory biomarkers, energy substrate utilization, and fatigue-related responses. Secondary outcomes include selected physiological and performance-related variables associated with recovery from high-intensity interval exercise.
The findings of this study will improve the understanding of the physiological responses to interval exercise in female basketball players and may contribute to the development of evidence-based training and recovery strategies aimed at optimizing performance and athlete health.
High-intensity intermittent exercise is a fundamental component of basketball and is characterized by repeated bouts of sprinting, jumping, rapid changes of direction, and brief recovery periods. This type of exercise places substantial demands on both aerobic and anaerobic energy systems and induces complex metabolic and inflammatory responses. Although numerous studies have investigated the physiological effects of high-intensity exercise, the interactions among exercise-induced inflammation, metabolic regulation, energy substrate utilization, and fatigue in female basketball players remain insufficiently understood.
The purpose of this study is to investigate the acute effects of basketball-specific interval exercise on metabolic and inflammatory responses, energy substrate utilization, and psychophysiological fatigue in trained female basketball players. The exercise stimulus will consist of the Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1), a validated field test that closely simulates the intermittent high-intensity demands of competitive basketball by requiring shuttle runs interspersed with short active recovery periods.
Participants will attend a single experimental session consisting of baseline assessments, completion of a standardized interval exercise protocol, and follow-up assessments during the early recovery period. Biological samples, physiological measurements, and fatigue assessments will be obtained at predefined time points before exercise, immediately after exercise, and one hour after exercise. Laboratory analyses will evaluate selected inflammatory and metabolic biomarkers together with indicators of energy substrate utilization. In addition, subjective fatigue and neuromotor performance will be assessed to characterize both peripheral and central aspects of exercise-induced fatigue.
To minimize potential confounding factors, participants will follow standardized pre-test instructions regarding physical activity, alcohol consumption, caffeine intake, and nutritional preparation before testing. Nutritional intake and anthropometric characteristics will also be documented to support the interpretation of physiological responses.
By integrating biochemical, metabolic, physiological, and psychophysiological measurements within a basketball-specific exercise model, this study aims to improve understanding of the mechanisms underlying acute responses to high-intensity intermittent exercise in female athletes. The findings may contribute to evidence-based strategies for monitoring training load, optimizing recovery, and improving performance in women's basketball and other intermittent team sports.
2,229 studies on the registry are indexed under Fatigue; 426 are open to participants now.
This study's planned enrollment of 25 is below the median of 54 across 1,757 interventional studies indexed under Fatigue.
Browse Fatigue studies →Poznan University of Physical Education is the lead sponsor of 90 studies on the registry; 27 are open to participants now.
Compared within Fatigue, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Motor Activity. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants assigned to this arm will complete a single session of the Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1), a standardized high-intensity intermittent exercise protocol designed to simulate the physiological demands of competitive basketball. Assessments will be conducted before exercise, immediately after exercise, and one hour after exercise to evaluate acute metabolic, inflammatory, physiological, and fatigue-related responses.
Other: Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1)
The intervention consists of the Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1), a standardized maximal intermittent field exercise test designed to reproduce the physiological demands of intermittent team sports such as basketball. Participants perform repeated 20-meter shuttle runs at progressively increasing speeds, guided by audio signals, with 10-second active recovery periods between running bouts. The test continues until volitional exhaustion or until the participant is unable to maintain the required running pace according to the test protocol. The Yo-Yo IR1 is used to induce acute physiological stress for the assessment of metabolic, inflammatory, and fatigue-related responses.
Change in Serum Interleukin-6 (IL-6) Concentration
Serum interleukin-6 (IL-6) concentration will be measured to assess the acute inflammatory response induced by the Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1). The outcome will be expressed as the change in IL-6 concentration across the predefined assessment time points.
Time frame: Baseline (pre-exercise), immediately after exercise, and 1 hour after exercise.
Change in Blood Lactate Concentration
Blood lactate concentration measured from capillary blood as an indicator of anaerobic metabolism following high-intensity intermittent exercise.
Time frame: Baseline and immediately after exercise.
Change in reaction time
Visual reaction time will be assessed as an indicator of neuromotor performance and central fatigue.
Time frame: Baseline and immediately post-exercise.
Change in serum-free fatty acid concentration
Serum free fatty acid concentration will be measured from venous blood samples to evaluate exercise-induced lipid mobilization.
Time frame: Baseline, immediately post-exercise, and 1 hour post-exercise
Change in blood glucose concentration
Blood glucose concentration will be measured using a portable glucometer with disposable test strips.
Time frame: Baseline, immediately post-exercise, and 1 hour post-exercise
Change in serum insulin concentration
Serum insulin concentration will be measured to assess hormonal regulation of glucose metabolism.
Time frame: Baseline, immediately post-exercise, and 1 hour post-exercise
Change in Rating of Perceived Exertion (Borg Scale)
Subjective perception of exercise intensity will be assessed using the Borg Rating of Perceived Exertion Scale. Total scores range from 6 to 20, with higher scores indicating greater perceived exertion during exercise.
Time frame: Immediately after exercise completion (within 5 minutes).
Change in mood state assessed by Profile of Mood States (POMS)
Mood state will be assessed using the validated Profile of Mood States questionnaire. Total scores range from 0 to 260, with higher scores indicating greater mood disturbance and psychological distress.
Time frame: Before exercise.
Plan to share: No — Individual participant data collected during this study will not be made publicly available.
Start is estimated for Sep 2026; primary completion for Nov 2026, 2 months later.
Of 936 non-industry interventional studies with no phase under Fatigue, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 27. This study's planned 2 months is below that.
Counting every sponsor, half of 989 studies reached it within 11 months; a quarter within 5 and three quarters within 27.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Poznan University of Physical Education