An interventional study of One-level Erector Spinae Plane Block and Bi-level Erector Spinae Plane Block in Pain, Postoperative, Breast Surgery and Erector Spinae Plane Block, sponsored by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital. Recruiting at 1 site in Turkey (Türkiye). Open to female participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · Not applicable, Interventional, and Treatment
Among 16 studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital — 6 open to participants now, 6 under way, none of them phase 3. Pain, Postoperative · Atatürk Chest Diseases and Chest Surgery Training and Research Hospital.
Among the 16 studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, this one is the 4th largest by planned enrollment of the 12 interventional ones, is one of 3 that started in 2026, is one of 12 with no phase, and was the 15th registered.
5,640 studies on the registry are indexed under Pain, Postoperative; 1,230 are open to participants now.
This study's planned enrollment of 70 is close to the median of 75 across 4,821 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →6 of the 16 studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital are open now, in 1 country. Each count lists the studies.
Of the 679 Pain, Postoperative studies recruiting now, 241 (35%) set no upper age limit and 328 (48%) stop at 75 or younger; 74 take children under 18; 128 take healthy volunteers.
This study: 18 Years to 80 Years · female · no healthy volunteers.
The full table on the hub →16 studies; the count open now beside each. This study's row is marked.
First in 2021; this study’s year is marked. 3 started in 2026.
Median enrollment 60 across the 12 interventional studies, 100 across the 4 observational. Of the 8 that completed or were terminated, 0 (0%) have results posted.
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital is the lead sponsor of 29 studies on the registry; 9 are open to participants now.
3 of the studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07429669Atatürk Chest Diseases and Chest Surgery Training and Research HospitalComparative Analgesia and Respiratory Effects of Shoulder Blocks | 2026-11-10 |
| NCT07747623Atatürk Chest Diseases and Chest Surgery Training and Research HospitalOne-level and Bi-level ESPB Application in Patients Undergoing Breast Surgery | 2027-01-10 |
| NCT07826741Atatürk Chest Diseases and Chest Surgery Training and Research HospitalIntrathecal Morphine and Transversalis Fascia Plane Block for Analgesia After Open Inguinal Hernia Repair | 2027-04-10 |
Among the 16 studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, from their registry updates:
Nothing recorded among them since 2026-09-25.
Acute pain after breast surgery can significantly reduce the quality of life for patients. If acute pain is not adequately treated, it can develop into chronic pain. Thoracic epidural analgesia, thoracic paravertebral block, erector spinae plane block, and serratus anterior plane block are frequently applied blocks. However, ESPB, being a fascial plane block, can yield inconsistent results regarding distribution and dermatomal area. In recent years, there has been an increase in publications applying ESPB from two levels to achieve wider distribution. As a result, this study aims to compare the analgesic efficacy of single-level (Thoracic 3) and two-level (Thoracic 2, Thoracic 4) ESPB applications.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
After the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T3 spinous process, 30 ml of 0.25% bupivacaine hydrochloride will be injected cauda-cranially into the interfacial space below the erector spinae muscle, above the transverse process.
Procedure: One-level Erector Spinae Plane Block
After the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T2 spinous process, 15 ml of 0.25% bupivacaine hydrochloride will be injected cauda-cranially into the interfacial space below the erector spinae muscle, above the transverse process. Next, the needle will be withdrawn till subcutaneously and the linear US probe will be placed 2-3 cm lateral to the T4 spinous process. Finally, 15 ml of 0.25% bupivacaine hydrochloride will be injected cranio-caudally into the interfacial space below the erector spinae muscle, above the transverse process.
Procedure: Bi-level Erector Spinae Plane Block
One-level Erector Spinae Plane Block will be performed unilaterally, under US guidance, before the surgical operation, and when the patient is placed in the lateral decubitus position. In applications, 30 ml of 0.25% bupivacaine will be injected at the T3 level.
Bi-level Erector Spinae Plane Block will be performed unilaterally, under US guidance, before the surgical operation, and when the patient is placed in the lateral decubitus position. In applications, 15 ml of 0.25% bupivacaine at T2 level and 15 ml of 0.25% bupivacaine at T4 level will be injected.
Pain scores
Pain will be assessed at the 4th-hour rest using the visual analog scale on a scale from 0 mm (no pain) to 100 mm (worst pain).
Time frame: 4th-hour after surgery
Pain scores
Pain will be assessed at rest using the visual analog scale on a scale from 0 mm (no pain) to 100 mm (worst pain). Pain assessment will be done at the 1st, 2nd, 12th, and 24th hours after surgery.
Time frame: Up to 24 hours after surgery
Pain scores
Pain will be assessed while coughing using the visual analog scale on a scale from 0 mm (no pain) to 100 mm (worst pain). Pain assessment will be done at the 1st, 2nd, 6th, 12th, and 24th hours after surgery.
Time frame: Up to 24 hours after surgery
Tramadol Consumption
Postoperative intravenous tramadol infusion therapy will be administered with the patient-controlled analgesia (PCA) method. Thanks to PCA, how much morphine the patient needs will be followed in mg.
Time frame: Up to 24 hours after surgery
Side effects
Side effects, such as allergy to local anesthetics, hypotension, nausea/vomiting, and itching, will be recorded.
Time frame: Up to 24 hours after surgery
Started Sep 2026 (actual). Primary completion is estimated for Jan 2027, 3 months after the start.
Of 2,089 non-industry interventional studies with no phase under Pain, Postoperative, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 23. This study's planned 3 months is below that.
Counting every sponsor, half of 2,102 studies reached it within 11 months; a quarter within 6 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
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Atatürk Chest Diseases and Chest Surgery Training and Research Hospital