ClinicalTrials.gg
RecruitingNCT05145153Updated May 2, 2024

Incidence of Chronic Pain After Thoracic Surgery

An observational study in Postoperative Pain, Postoperative Pain, Acute and Postoperative Pain, Chronic, sponsored by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital. Recruiting at 1 site in Turkey. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-05-02.

Sponsored by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · Observational

From the registry’s dates

  • Primary completion was expected by Oct 2024, 2 years 1 month ago, but the record still lists the study as recruiting.
  • Started Sep 2021; still recruiting 5 years 1 month later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Ages
18 Years to 65 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 16 studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital — 6 open to participants now, 6 under way, none of them phase 3. Pain, Postoperative · Atatürk Chest Diseases and Chest Surgery Training and Research Hospital.

Started
2021
with 9 others
Observational
4 of 16
2 open now
Registered
7th of 16
by date

Among the 16 studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, this one is one of 10 that started in 2021, is one of 4 observational ones, and was the 7th registered.

By phase

16 studies; the count open now beside each. This study's row is marked.

No phase12 · 4 open
Observationalthis study4 · 2 open

By the year they started

First in 2021; this study’s year is marked. 10 started in 2021.

Size and results

Median enrollment 60 across the 12 interventional studies, 100 across the 4 observational. Of the 8 that completed or were terminated, 0 (0%) have results posted.

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Watch this landscapeDownload CSVWith an account: a weekly mail of what changed among 16 studies in Pain, Postoperative by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, or all of them as a file.
02

Study summary

Thoracotomy and video-assisted thoracic surgery procedures are frequently performed in thoracic surgery. It is widely accepted that thoracotomy causes severe acute pain. This prolongs the discharge time of the patients, and increases the frequency of postoperative pulmonary complications and postoperative morbidity. Postoperative acute pain may cause chronic thoracotomy pain in the later period, and may adversely affect the quality of life of the patients. Video-assisted thoracic surgery (VATS) has become the standard procedure in minor and major lung surgeries. Postoperative pain is seen in patients undergoing VATS, although it is not as severe as after thoracotomy. As in thoracotomy, this affects the postoperative pulmonary complications and the discharge time of the patients. Likewise, this pain can cause chronic pain.

In this study, it was aimed to analyze the symptoms of chronic pain in the 3rd and 6th months postoperatively in patients who had undergone thoracic surgery.

03

Conditions studied

  • Postoperative Pain
  • Postoperative Pain, Acute
  • Postoperative Pain, Chronic
  • Video-Assisted Thoracoscopic Surgery
  • Thoracotomy

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Keywords

  • Postoperative Pain
  • Postoperative Pain, Acute
  • Postoperative Pain, Chronic
  • Video-Assisted Thoracoscopic Surgery
  • Thoracotomy
04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients between the ages of 18-65 years, in the ASA I-II-III risk group, with a BMI between 18-35 kg/m2 and undergoing thoracic surgery will be included in our study.

Patients under the age of 18 years and over the age of 65 years, with an ASA score of IV and above, with a BMI below 18 kg/m2 and above 35 kg/m2, who were operated under emergency conditions, and who received chronic pain treatment will be excluded from the study.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age between 18 and 65 years
  • physical status I-II-III
  • between 18-35 kg/m2
  • Patients undergoing elective thoracic surgery

Exclusion criteria

Exclusion Criteria:

  • Advanced cancer
  • History of chronic analgesic therapy
  • Patients with previous thoracic surgery
  • Patients who were operated under emergency conditions
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

ASA physical status

The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (estimated)
Patient registry
No

Interventions

  • ProcedureThoracic surgery application

    The chronic pain findings of the patients who underwent thoracic surgery will be questioned at the postoperative 3rd and 6th months.

06

What researchers measure

Primary outcomes

  1. Pain scores at 3th months.

    Choronic pain symptoms will be assessed using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Neuropathic pain symptoms (Burning, stabbing, electric shock-like pain, tingling, numbness, pins and needles feeling, hyperalgesia, allodynia, and hypoesthesia) will also be asked to the patients in the 3rd month after surgery.

    Time frame: Chronic pain symptoms at 3th months.

  2. Pain scores at 6th months.

    Choronic pain symptoms will be assessed using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Neuropathic pain symptoms (Burning, stabbing, electric shock-like pain, tingling, numbness, pins and needles feeling, hyperalgesia, allodynia, and hypoesthesia) will also be asked to the patients in the 6th month after surgery.

    Time frame: Chronic pain symptoms at 6th months.

Secondary outcomes

  1. Life quality

    It will be questioned whether chronic pain affects the patient's quality of life. 1. has no affect 2. has little effect 3. has medium affect 4. has a lot of affects

    Time frame: The effect of chronic pain on quality of life at 3rd and 6th months.

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Sep 2021 (actual). Primary completion is estimated for Oct 2024, 36 months after the start.

Of 391 non-industry observational studies under Pain, Postoperative, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 32. This study's planned 36 months is above that.

Counting every sponsor, half of 395 studies reached it within 13 months; a quarter within 5 and three quarters within 33.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 18, 2021
First posted
Dec 6, 2021
StartActual
Sep 28, 2021
Primary completionEst.
Oct 8, 2024
CompletionEst.
Nov 28, 2024
Last update
May 2, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 2, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05145153
Lead sponsor
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Responsible party
Musa Zengin (Principal İnvestigator, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital) — Principal investigator
First posted
Dec 6, 2021
Start date
Sep 28, 2021
Primary completion
Oct 8, 2024 (estimated)
Completion
Nov 28, 2024 (estimated)
Last update
May 2, 2024

Study contacts

Musa Zengin, MD
Contact
musazengin@gmail.com
903125677233
Ali Alagoz, Assoc Prof
Contact
mdalagoz@gmail.com
+903125677232
Musa Zengin, MD
principal investigator · Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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