An interventional study of Resin based fissure sealant (Fisseal) and Giomer based fissure sealant ( Beautisealant) in Molar Hypomineralization, Incisor, Fissure Sealant and Resin Based Sealers, sponsored by National Research Centre, Egypt. Completed at 1 site in Egypt. Open to participants aged 6 Years to 12 Years. Per ClinicalTrials.gov, last updated 2026-07-29.
Sponsored by National Research Centre, Egypt · Not applicable, Interventional, and Treatment
This study aims to compare the effect of two types of fissure sealant a resin based and giomer based in molar incisor hypominerlisation first permanent molars
121 studies on the registry are indexed under Molar Hypomineralization; 41 are open to participants now.
This study's enrollment of 22 is below the median of 52 across 94 interventional studies indexed under Molar Hypomineralization.
Browse Molar Hypomineralization studies →National Research Centre, Egypt is the lead sponsor of 49 studies on the registry; 4 are open to participants now.
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Apparently Healthy Children aged 6-12 years having at least one fully erupted First Permanent Molar (FPM) with MIH indicated for non-invasive fissure sealant.
Exclusion Criteria:
Fisseal is a light-curing, fluoride-releasing pit and fissure sealant. the occlusal surfaces will be etched with 37% phosphoric acid for 30 seconds, rinsed with air-water spray for 30 s and dried with air for 15 s. resin sealant (Fisseal) then applied into the occlusal fissures and light-cured for 20 s.
Other: Giomer based fissure sealant ( Beautisealant)
Beautisealant is a fluoride-releasing pit and fissure sealant that features Giomer technology. the self-etch primer (BeautiSealant Primer) will be applied to the occlusal fissures with a fine micro brush. After waiting for 5 s, and homogenizing the bond layer with gentle air stream for 5 s, the giomer sealant (BeautiSealant Paste) will be placed and light-cured for 20 s.
Other: Resin based fissure sealant (Fisseal)
Fisseal is a light-curing, fluoride-releasing pit and fissure sealant. composition: Methacrylate Monomers, Inorganic Fillers, Photoinitiator System and Sodium Fluoride.
BeautiSealant is a fluoride-releasing pit and fissure sealant that features Giomer technology. it's BPA- and HEMA-free pit and fissure sealant. it's composition: S-PRG (Surface Pre-Reacted Glass) Fillers, UDMA (Urethane Dimethacrylate), TEGDMA (Triethylene Glycol Dimethacrylate), Micro Fumed Silica.
Evaluate the clinical success of giomer and conventional resin-based sealants applied on first permanent molars (FPMs) affected by MIH.
Time frame: 12 months
number of tooth with failed fissure sealant
Fissure sealants will be checked under artificial light with a dental mirror and straight explorer. The sealants that will receive "Alpha" or "Bravo" scores from all of the USPHS Criteria (anatomic form, marginal adaptation, surface texture, marginal discoloration, retention and secondary caries) will be classified as successful. On the other hand, "Charlie" score from one or more of the USPHS criteria will be considered as a failure.
Time frame: 12 months
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Plan to share: No
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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National Research Centre, Egypt