An interventional study of single visit root canal treatment using ProTaper Universal rotary system and single visit root canal treatment using M-Pro rotary system in Symptomatic Irreversible Pulpitis, sponsored by National Research Centre, Egypt. Enrolling by invitation at 1 site in Egypt. Open to participants aged 25 Years to 45 Years. Per ClinicalTrials.gov, last updated 2025-01-15.
Sponsored by National Research Centre, Egypt · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to compare the post-operative pain occurrence after single visit root canal treatment using Two NiTi Rotary Files. The main question it aims to answer is:
Participants will receive single visit endodontic treatment using either ProTaper or MPro systems for root canal preparation.
Participants will record Pain intensity at 24 hours and 7 days post-operative. Analgesics will be prescribed for the patients in need.
The main cause of patient fear is expecting pain during root canal treatment. It is considered a major concern for dentists as well. During root canal preparation, periapical extrusion of pulpal tissue remnants, microorganisms or dentin chips may be one of the causes of postoperative pain. Depending on the fact that, instrument design and instrumentation techniques have an impact on the amount of extruded debris apically, many studies proved the ability of some rotary systems to reduce debris extrusion, permitting to achieve less pain sensation.
Therefore, the present clinical study aims to compare the postoperative pain intensity in molars with symptomatic irreversible pulpitis after single endodontic treatment visit using a full-sequence rotary Ni-Ti system either ProTaper or MPro systems Eighty patients with symptomatic irreversible pulpitis in mandibular first molars will be assigned into two groups. In group A (n=40): root canal preparation will be performed in single visit using ProTaper Universal system and in group B (n=40): root canal preparation will be performed in single visit using M-Pro rotary system. Pain intensity will be recorded by the patient using Numerical Rating Scale (NRS) at 24 hours and 7 days postoperative. Analgesics will be prescribed for the patients in case of need.
5,640 studies on the registry are indexed under Pain, Postoperative; 1,230 are open to participants now.
This study's planned enrollment of 80 is close to the median of 75 across 4,821 interventional studies indexed under Pain, Postoperative.
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Exclusion Criteria:
root canal treatment will be performed in single visit using ProTaper Universal system
Procedure: single visit root canal treatment using ProTaper Universal rotary system
root canal treatment will be performed in single visit using M-Pro rotary system
Procedure: single visit root canal treatment using M-Pro rotary system
single visit endodontic treatment will be performed using ProTaper Universal rotary system for root canal preparation.
single visit endodontic treatment will be performed using MPro rotary systems for root canal preparation.
Record the intensity of postoperative pain after root canal treatment with ProTaper Universal and M-Pro endodontic rotary files.
Pain intensity will be recorded by the patient 24 hours and 7 days postoperatively. Pain assessment is evaluated using 10-point Numerical Rating Scale, where the endpoints are the extremes of no pain and worst pain. The severity of pain is assigned as follows: (0) equivalent to none/ (1) equivalent to slight pain / (2) equivalent to moderate pain and (3) equivalent to severe pain.
Time frame: 7 days
Plan to share: Yes
Supporting information: Study protocol
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National Research Centre, Egypt