ClinicalTrials.gg
Not yet recruitingNCT07661524Updated Oct 8, 2026

Passive Versus Active Music Therapy Parkinson's Disease

An interventional study of Passive music therapy and Active music therapy in Parkinson Disease (PD), sponsored by University of Alabama at Birmingham. Not yet recruiting at 2 sites in United States. Open to participants aged 50 Years to 89 Years. Per ClinicalTrials.gov, last updated 2026-10-08.

Sponsored by University of Alabama at Birmingham · Not applicable, Interventional, and Treatment

Updated Oct 8, 2026Start date moved1 site addedGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
28
Allocation
Randomized
Ages
50 Years to 89 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 24 studies in Parkinson Disease by University of Alabama at Birmingham — 8 open to participants now, 9 under way, none of them phase 3. Parkinson Disease · University of Alabama at Birmingham.

Planned enrollment
13th of 20
28 · median 35
Started
2026
with 1 other
No phase
17 of 24
5 open now
Registered
23rd of 24
by date

Among the 24 studies in Parkinson Disease by University of Alabama at Birmingham, this one is the 13th largest by planned enrollment of the 20 interventional ones, is one of 2 that started in 2026, is one of 17 with no phase, and was the 23rd registered.

By phase

24 studies; the count open now beside each. This study's row is marked.

No phasethis study17 · 5 open
Observational4 · 0 open
Phase 12 · 2 open
Phase 1/21 · 1 open

By the year they started

First in 2010; this study’s year is marked. 2 started in 2026.

Size and results

Median enrollment 35 across the 20 interventional studies, 117 across the 4 observational. Of the 14 that completed or were terminated, 4 (29%) have results posted.

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Watch this landscapeDownload CSVWith an account: a weekly mail of what changed among 24 studies in Parkinson Disease by University of Alabama at Birmingham, or all of them as a file.
02

Study summary

The purpose of this pilot study is to identify the effects of active versus passive music therapy on functional ability and psychophysiological responses to goal-directed exercise in people with Parkinson's disease.

Read the detailed description

Using a crossover counterbalanced approach, participants with idiopathic PD (n=28) will be recruited to complete 3 separate experimental visits each with a differing condition: 1) No music (control; CON), 2) PMT, 3) AMT. For each condition, participants will complete a battery of functional testing (sit-to-stand test; STS) and goal-based exercise (6-minute walk test; 6MWT) separated by 20-minutes of rest. Functional ability will be determined via biomechanical parameters (i.e. peak force, braking force, rate of force development) during the 5-time STS test. Exercise capacity (i.e. distance, average walking velocity) will be determined for goal-based exercise during the 6MWT. During each test, a medical grade smartwatch will record psychophysiological (i.e. heart rate, metabolic equivalents, electrodermal activity) responses. Furthermore, psychometric testing for motivation, enjoyment, psychological arousal, fatigue, and rating of perceived exertion will be conducted after each test attempt.

03

Conditions studied

  • Parkinson Disease (PD)

Keywords

  • Music therapy
  • Exercise
  • Motivation
  • Parkinson's
  • Neurodegeneration
04

Who can participate

Ages eligible
50 Years to 89 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Formal diagnosis of idiopathic PD
  • Hoen \& Yahr Stage \<III
  • Middle or old age onset of PD (at least 50 years of age)
  • The ability to ambulate without assistive devices
  • Stable medication regimen for four weeks prior to participation
  • No changes to treatment of PD in the last month.

Exclusion criteria

Exclusion Criteria:

  • Primary psychiatric disease (non-PD related)
  • Reports of falling in the last six weeks
  • Any reason a participant or their healthcare team believed their participation in the study could negatively impact their well-being.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
28 participants (estimated)

Study arms

  • No intervention
    Control

    No music therapy

  • Experimental
    Active music therapy

    Music therapy with a licensed music therapist

    Behavioral: Active music therapy

  • Experimental
    Passive music therapy

    Listening to self-selected music

    Behavioral: Passive music therapy

Interventions

  • BehavioralPassive music therapy

    Listening to self-selected music

  • BehavioralActive music therapy

    Structured music therapy with a licensed music therapist

06

What researchers measure

Primary outcomes

  1. Average time sit to stand

    Time to complete 5 sit to stand test

    Time frame: Week 1, Week 2

  2. Total walking distance accumulated in 6 minutes

    Total distance in meters accumulated during a six minute walk test

    Time frame: Week 1, Week 2

  3. Total motivation level

    Motivation levels as assessed by a visual analog scale on 0 to 100 where 0 equals the absence of motivation and 100 indicates extremely motivated

    Time frame: Week 1, Week 2

07

Study locations

2 sites
08

References and documents

Publications

  • Porrill SL, Allendorfer JB, Evancho AM, Ferguson CC, LaChenaye JM, Nguyen HM, Rogers RR, Ballmann CG. Effects of self-selected music on psychophysiological responses to goal-directed exercise in Parkinson's disease. Front Rehabil Sci. 2026 Apr 14;7:1778451. doi: 10.3389/fresc.2026.1778451. eCollection 2026. PubMed 42058676 ↗

Individual participant data

Plan to share: Yes — All IPD that underlie results in a publication

Supporting information: Study protocol, Informed consent form

Time frame: Beginning 1 year after publication with no end date

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it movedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Nov 2026; primary completion for Oct 2027, 11 months later.

Of 1,291 non-industry interventional studies with no phase under Parkinson Disease, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 44. This study's planned 11 months is below that.

Counting every sponsor, half of 1,367 studies reached it within 25 months; a quarter within 11 and three quarters within 44.

Start moved once since we started tracking on Sep 25, 2026: Oct 2026 → Nov 2026, on Oct 8, 2026.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Jun 16, 2026
First posted
Jun 22, 2026
StartEst.
Nov 1, 2026was Oct 2026
Primary completionEst.
Oct 1, 2027
CompletionEst.
Dec 1, 2027
Last update
Oct 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Sites
1 site added
Show site
  • University of Alabama at Birmingham · Birmingham, United States
Oct 8, 2026
Start date
Oct 1, 2026→Nov 1, 2026
Oct 8, 2026
Show all 1 update
  1. Oct 8, 2026
    1 site added
    Show site
    • University of Alabama at Birmingham · Birmingham, United States
    Start date Oct 1, 2026→Nov 1, 2026
    + 1 other change: verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07661524
Collaborators
Rooted Music Therapy
Responsible party
Christopher Ballmann (Associate Professor, University of Alabama at Birmingham) — Principal investigator
First posted
Jun 22, 2026
Start date
Nov 1, 2026 (estimated)
Primary completion
Oct 1, 2027 (estimated)
Completion
Dec 1, 2027 (estimated)
Last update
Oct 8, 2026

Study contacts

Christopher G Ballmann, PhD
Contact
cgb0002@uab.edu
205-975-0613
Christopher G Ballmann, PhD
principal investigator · University of Alabama at Birmingham

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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