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Not yet recruitingNCT07633782Updated Jun 8, 2026

High-Intensity Focused Electromagnetic Therapy on Patients With Patellofemoral Pain Syndrome

An interventional study of True High-Intensity Focused Electromagnetic Therapy and Sham High-Intensity Focused Electromagnetic Therapy in Patellofemoral Pain Syndrome, sponsored by Middle East University. Not yet recruiting. Open to participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-06-08.

Sponsored by Middle East University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years to 45 Years
Sex
All
01

Study summary

Evaluate the effect of High-Intensity Focused Electromagnetic Therapy on pain, quadriceps strength, and quality of life in patients with patellofemoral pain syndrome

Read the detailed description

Patients diagnosed with patellofemoral pain syndrome will be recruited from outpatient physical therapy clinics. Following a comprehensive clinical screening, eligible participants will be randomly assigned into two parallel groups:

The Study Group: Will receive true High-Intensity Focused Electromagnetic Therapy sessions plus a traditional physiotherapy program for 8 weeks.

The Control Group: Will receive sham High-Intensity Focused Electromagnetic Therapy sessions plus the same traditional physiotherapy program for 8 weeks.

02

Conditions studied

  • Patellofemoral Pain Syndrome
03

Who can participate

Ages eligible
18 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Clinical diagnosis of patellofemoral pain syndrome (anterior or peripatellar knee pain aggravated by at least two activities such as stair climbing, prolonged sitting, squatting, or running).
  • Symptoms persisting for at least 3 months.

Exclusion criteria

Exclusion Criteria:

  • History of previous knee surgery or trauma (e.g., ligamentous laxity, meniscal tear, or patellar fracture).
  • Concomitant knee pathology (e.g., tibiofemoral osteoarthritis, patellar tendinopathy, or plica syndrome).
  • Presence of metallic implants, pacemakers, or electrical medical devices in the body .
  • Recent corticosteroid or hyaluronic acid injection into the affected knee within the last 3 months.
  • Pregnancy.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
60 participants (estimated)

Study arms

  • Active comparator
    Study group

    Device: True High-Intensity Focused Electromagnetic Therapy · Other: Traditional Physiotherapy

  • Sham comparator
    Control group

    Device: Sham High-Intensity Focused Electromagnetic Therapy · Other: Traditional Physiotherapy

Interventions

  • DeviceTrue High-Intensity Focused Electromagnetic Therapy

    20-30 minute sessions, 2-3 times per week for 8 weeks at a clinically effective, tolerable intensity level designed to elicit supramaximal contractions for the quadriceps muscle.

  • DeviceSham High-Intensity Focused Electromagnetic Therapy

    The device protocol, application time, and acoustic feedback will the same as the experimental arm, but with the device in the off state and no muscular contractions in the quadriceps muscle .

  • OtherTraditional Physiotherapy

    Standard rehabilitation program including patellar mobilization with quadriceps and hip abductor strengthening.

05

What researchers measure

Primary outcomes

  1. Pain level

    Visual Analog Scale will be used to assess pain

    Time frame: Baseline and after 8 weeks

Secondary outcomes

  1. Quadriceps muscle strength

    Isokinetic dynamometry will be used for assessing quadriceps muscle strength

    Time frame: Baseline and after 8 weeks

  2. Health-related quality of life

    Short Form-12 Health Survey (SF-12) will be used to assess QoL

    Time frame: Baseline and after 8 weeks

06

Study locations

No study locations are listed for this record.

07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07633782
Lead sponsor
Middle East University
Responsible party
Saher Lotfy El Gayar (Assistant Professor of Physiotherapy, Middle East University) — Principal investigator
First posted
Jun 8, 2026
Start date
Jun 12, 2026 (estimated)
Primary completion
Oct 1, 2026 (estimated)
Completion
Oct 8, 2026 (estimated)
Last update
Jun 8, 2026

Study contacts

Saher Lotfy Elgayar, Ph.D
Contact
saherlotfy020@gmail.com
+201020429911
Mohammed Youssef Elhamrawy, Ph.D
Contact
dr_melhamrawy@yahoo.com
+201282805567

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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