An interventional study of Mobilization with Movement and No mobilization with movement and education in Patellofemoral Pain, sponsored by Loma Linda University. Recruiting at 1 site in United States. Open to female participants aged 18 Years to 59 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-20.
Sponsored by Loma Linda University · Not applicable, Interventional, and Other
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Among 52 studies in Patellofemoral Pain Syndrome with a site in United States — 10 open to participants now, 12 under way, 1 of them phase 3. Patellofemoral Pain Syndrome · United States.
Among the 52 studies in Patellofemoral Pain Syndrome with a site in United States, this one is the 14th largest by planned enrollment of the 47 interventional ones that give a count, is one of 3 that started in 2022, is one of 43 with no phase, reaches primary completion later than 6 of the 10 other live ones, and was the 40th registered.
297 studies on the registry are indexed under Patellofemoral Pain Syndrome; 74 are open to participants now.
Browse Patellofemoral Pain Syndrome studies →10 of the 52 studies in Patellofemoral Pain Syndrome with a site in United States are open now. Recruiting first, the newest first:
University of Kansas Medical Center · Sites in United States
Ages 18+
Sara Gorczynski, PT, DPT · Sites in United States
Ages 18+
Womack Army Medical Center · Sites in United States
Ages 18–50
University of Nevada, Las Vegas · Sites in United States
Ages 18–45
University of Texas at Austin · Sites in United States
Ages 10–17 · Healthy volunteers
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 45 Patellofemoral Pain Syndrome studies recruiting now, 3 (7%) set no upper age limit and 41 (91%) stop at 75 or younger; 7 take children under 18; 13 take healthy volunteers.
This study: 18 Years to 59 Years · female · healthy volunteers too.
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52 studies; the count open now beside each. This study's row is marked.
First in 2003; this study’s year is marked. 3 started in 2022.
This study's planned enrollment of 60 is above the median of 45 across 244 interventional studies indexed under Patellofemoral Pain Syndrome.
Median enrollment 40 across the 47 interventional studies, 35 across the 5 observational. Of the 38 that completed or were terminated, 8 (21%) have results posted.
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2 of 52 have an industry lead sponsor. The 10 most frequent:
Loma Linda University is the lead sponsor of 306 studies on the registry; 46 are open to participants now.
Of its 29 completed or terminated interventional studies of FDA-regulated products, 23 (79%) have results posted.
Loma Linda University has 2 studies filed under Patellofemoral Pain Syndrome — fewer than ten, so there is no comparison to draw.
4 of the studies in Patellofemoral Pain Syndrome with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07472088University of Kansas Medical CenterAssessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms | 2026-11 |
| NCT05403944University of ConnecticutStrength or Power Training for Patellofemoral Pain | 2026-12-15 |
| NCT05285007Loma Linda UniversityLimited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain | 2027-05 |
| NCT06665204Sara Gorczynski, PT, DPTEvaluating the Effectiveness of Clinical Practice Guideline Adherence for Patellofemoral Pain | 2027-09-29 |
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Among the 52 studies in Patellofemoral Pain Syndrome with a site in United States, from their registry updates:
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The purpose of this graduate student research study is to investigate the relationship between limited ankle dorsiflexion and the potential effects on a single limb squat task in the Patellofemoral/Knee Pain population.
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Exclusion Criteria:
The experimental group will receive two interventions to increase dorsiflexion range of motion.
Other: Mobilization with Movement
The minimal intervention group will read and infographic and complete 5 minutes of treadmill walking.
Other: No mobilization with movement and education
Participants will be lunging on a box with posterior ankle glide of 10 seconds times 5 sets. They will have 30 seconds rest between trials. Participant will have their ankle taped and then walk on a treadmill at a self-selected pace for 5 minutes.
Participants ankle will not be taped and they will walk on the treadmill for 5 minutes and receive education.
Weight bearing lunge test
This test is used to assess a participant's available dorsiflexion range of motion in a weight bearing position. Furthermore, this places the participants hip, knee, and ankle into a flexed position which correlates with the squat tests we will be using.
Time frame: change between baseline and post intervention on Day 1
Patellofemoral Disability Index
The Index is a self-reported questionnaire that addresses the amount of pain a person may have during tasks such as running, jumping, and stair climbing.
Time frame: change between baseline and post intervention on Day 1
Started Mar 2022 (actual). Primary completion is estimated for May 2027, 62 months after the start.
Of 153 non-industry interventional studies with no phase under Patellofemoral Pain Syndrome, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 20. This study's planned 62 months is above that.
Counting every sponsor, half of 157 studies reached it within 11 months; a quarter within 4 and three quarters within 21.
How these figures are worked out, and which studies are left out of them.
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Patellofemoral Pain Syndrome →