ClinicalTrials.gg
Not yet recruitingNCT07596732SUNRISEUpdated May 19, 2026

Statewide Unified Network for Remote Intervention of Strength and Exercise

An interventional study of Exercise and Stretching in Gastric Cancer (Diagnosis), Esophagus Cancer and Pancreas Cancer, sponsored by AdventHealth Translational Research Institute. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-19.

Sponsored by AdventHealth Translational Research Institute · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
120
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study will evaluate whether a remotely delivered exercise program can improve chemotherapy tolerability in patients with gastrointestinal or lung cancer receiving chemotherapy.

In this decentralized, digital randomized clinical trial, up to 120 adults with gastrointestinal or lung cancer will be randomized to either a home-based aerobic and resistance exercise program or home-based progressive stretching program. All study activities will be conducted remotely using digital technologies and home-based assessments. Participants in both groups will receive Bluetooth-enabled wearable devices for monitoring physical activity, body weight, blood pressure, and other health measures.

The primary objective is to determine whether exercise improves chemotherapy relative dose intensity compared with stretching. The intervention will continue throughout chemotherapy treatment or for up to 32 weeks.

02

Conditions studied

  • Gastric Cancer (Diagnosis)
  • Esophagus Cancer
  • Pancreas Cancer
  • Colon Cancer
  • Rectal Cancer
  • Lung Cancer
03

In context

Stomach Neoplasms

3,399 studies on the registry are indexed under Stomach Neoplasms; 992 are open to participants now.

This study's planned enrollment of 120 is above the median of 66 across 2,499 interventional studies indexed under Stomach Neoplasms.

Browse Stomach Neoplasms studies →

Lead sponsor

AdventHealth Translational Research Institute is the lead sponsor of 57 studies on the registry; 11 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Gastrointestinal cancer (esophageal, gastric, pancreatic, colon, and rectal) treated with chemotherapy (and other treatments, as clinically indicated) before surgery OR Lung cancer (non-small cell and small-cell) treated with chemotherapy (and other treatments, as clinically indicated) for advanced- or extensive-stage disease.
  • Completion of the modified version of the Physical Activity Readiness Questionnaire.

Exclusion criteria

Exclusion Criteria:

  • Actively treated for another non-gastrointestinal or non-lung (surveillance with observation is allowed).
  • Engage in more than 150 minutes per week of aerobic physical activity and two or more sessions of muscle strengthening activity per week over the last three months (self-report).
  • Unable to walk for 6 minutes or two city blocks independently (self-report).
  • Enrollment in another study that intervenes upon physical activity, diet, or body composition as a primary objective (self-report).
  • Unable to read and speak English.
  • No access to a reliable internet connection.
  • Currently an AdventHealth employee.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
120 participants (estimated)

Study arms

  • Experimental
    Exercise

    The exercise group will engage in aerobic and muscle-strengthening activities.

    Behavioral: Exercise

  • Active comparator
    Stretching

    The stretching group will engage in whole-body static stretching activities.

    Behavioral: Stretching

Interventions

  • BehavioralExercise

    The exercise group will be provided with Bluetooth-enabled devices and home exercise equipment. Participants will meet with an exercise trainer weekly to learn how to engage in the exercise program.

  • BehavioralStretching

    The stretching group will be provided with Bluetooth-enabled devices. Participants will meet with an exercise trainer weekly to learn how to engage in the stretching program.

06

What researchers measure

Primary outcomes

  1. Chemotherapy Relative Dose Intensity

    The ratio of the delivered dose intensity to the standard or planned dose intensity.

    Time frame: Up to 32 weeks

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 19, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07596732
Lead sponsor
AdventHealth Translational Research Institute
Responsible party
Justin Brown (Director, Exercise & Cancer Biology Research Program, AdventHealth Translational Research Institute) — Principal investigator
First posted
May 19, 2026
Start date
Jul 1, 2026 (estimated)
Primary completion
Aug 31, 2027 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
May 19, 2026

Study contacts

Marcus Perez
Contact
Marcus.Perez@AdventHealth.com
407-303-5642
Abigail Tice, Ph.D.
Contact
Abigail.Tice@AdventHealth.com
Justin Brown, Ph.D.
principal investigator · AdventHealth

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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