An observational study in Thyroid Diseases, Goiter and Thyroid Neoplasms, sponsored by Assiut University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-05-12.
Sponsored by Assiut University · Observational
Thyroidectomy is generally considered a low-to-moderate risk operation; however, postoperative pain, nausea/vomiting, and prolonged hospital stays remain common issues. Enhanced Recovery After Surgery (ERAS) pathways aim to optimize perioperative care and accelerate recovery. This study evaluates the effectiveness and safety of a standardized ERAS pathway in patients undergoing elective thyroidectomy. The prospective ERAS cohort is compared with a historical control group receiving conventional care to assess the impact on the length of hospital stay, postoperative pain, opioid consumption, and complication rates.
Patients scheduled for elective thyroidectomy for benign or malignant disease at a tertiary cancer institute
Exclusion Criteria:
A prospective cohort undergoing elective thyroidectomy under an ERAS protocol.
Procedure: Enhanced Recovery After Surgery protocol
A historical control cohort undergoing thyroidectomy under conventional care during the 12 months preceding ERAS implementation
Procedure: Conventional perioperative care
This incorporates standardized preoperative counseling, reduced fasting, multimodal opioid-sparing analgesia, total intravenous anesthesia, selective drain use, early oral intake and mobilization, and PTH-guided calcium supplementation
Also known as: ERAS
This often involves prolonged preoperative fasting, opioid-based analgesia, and delayed mobilization
Length of hospital stay
Hours from surgery end to discharge
Time frame: Up to 30 days post-surgery
Postoperative pain scores
Mean Numeric Rating Scale (NRS-11; 0 = no pain to 10 = worst imaginable pain) at rest in 24 hours. NRS scores are categorized as mild (1-3), moderate (4-6), or severe (7-10).
Time frame: Assessed in the first 24 hours postoperatively
Total opioid consumption
Oral Morphine Milligram Equivalents (MME)
Time frame: Within first 24 hours
Postoperative nausea and vomiting (PONV)
Incidence of PONV
Time frame: Up to 24 hours postoperatively
Rate of postoperative hypocalcemia
Biochemical and symptomatic occurrences
Time frame: First 30 days from the surgery
30-day unplanned readmission rate
Number of unplanned readmissions
Time frame: Up to 30 days postoperative
Plan to share: No
This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Assiut University