An interventional study of laparscopic staging in Treatment Endometrial Cancer, sponsored by Ain Shams Maternity Hospital. Not yet recruiting. Open to female participants. Per ClinicalTrials.gov, last updated 2026-04-07.
Sponsored by Ain Shams Maternity Hospital · Not applicable, Interventional, and Treatment
Compared with laparotomy, laparoscopy is associated with faster recovery, better visualization, shorter hospital stays, and less possible adhesion formation. But do the safety, efficacy, and morbidity of laparoscopic staging differ from conventional staging laparotomy in endometrial cancer?Is laparoscopic staging considered a safe and effective alternative procedure for the surgical treatment of early-stage endometrial carcinoma? This study aims to compare the safety, efficacy, and morbidity between total laparoscopic hysterectomy (TLH) with lymphadenectomy and conventional staging laparotomy for early-stage endometrial cancer.
Primary Outcome: perioperative morbidities:
Secondary outcomes:
1,425 studies on the registry are indexed under Endometrial Neoplasms; 473 are open to participants now.
This study's planned enrollment of 30 is below the median of 71 across 1,026 interventional studies indexed under Endometrial Neoplasms.
Browse Endometrial Neoplasms studies →Ain Shams Maternity Hospital is the lead sponsor of 139 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria:• Inclusion Criteria:
I. Patient histopathological diagnosed early-stage endometrial carcinoma, (stages 1A \&1B) according to FIGO classification.
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Exclusion Criteria:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Neoadjuvant treatment is given before the main treatment (usually surgery), often to shrink a tumour. Adjuvant treatment is given after it, to lower the chance of the cancer coming back.
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Adjuvant and neoadjuvant
Neoadjuvant treatment is given before the main treatment (usually surgery), often to shrink a tumour. Adjuvant treatment is given after it, to lower the chance of the cancer coming back.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Metastases
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
laparoscopic staging
Procedure: laparscopic staging
staging laparotomy
Procedure: laparscopic staging
staging laparotomy
Also known as: staging laparotomy
Primary Outcome: perioperative morbidities. intraoperative complications like bladder, ureteric, or intestinal injury
Primary Outcome: perioperative morbidities: . intraoperative complications like bladder, ureteric, or intestinal injury
Time frame: 6 months
Secondary outcomes: 1. Amount of blood loss by the allowable blood loss formula
Secondary outcomes: Amount of blood loss by allowable blood loss formula between conventional staging laparotomy and laparoscopic staging \& need for blood transfusion. (ABL = weight kg \* age sex factor (65ml/ kg) \*initial HGB(g/dl)-final HGB(g/dl) / initial HGB (g/dl) (Jaramillo, 2019).
Time frame: 6 months
postoperative pain by visual analog pain scale
postoperative pain by the visual analog pain scale
Time frame: 6 months
oncological outcome like need for post-operative chemo or radiotherapy
oncological outcome like need for post-operative chemo or radiotherapy
Time frame: 6 months
No study locations are listed for this record.
Plan to share: Undecided
Start is estimated for Apr 2026; primary completion for Oct 2026, 6 months later.
Of 195 non-industry interventional studies with no phase under Endometrial Neoplasms, half reached primary completion within 44 months of starting (the median), counting those still running; a quarter within 20 and three quarters within 76. This study's planned 6 months is below that.
Counting every sponsor, half of 201 studies reached it within 43 months; a quarter within 19 and three quarters within 76.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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